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October 15, 2025 20 mins

What if the future of healthcare innovation wasn’t defined by technology, but by global collaboration, data sharing, and integrity-driven science?

In this episode of Lightning RX, host Colette Nataf sits down with Dr. Ravi Mehrotra, Physician-Scientist at the Rollins School of Public Health at Emory University and Founder of the Open Health Systems Laboratory (OHSL), to explore how open collaboration and informatics are transforming cancer prevention and public health worldwide.

Dr. Mehrotra shares his journey from the Armed Forces Medical College in India to leading a global network of scientists, clinicians, and technologists dedicated to advancing cancer research and care across borders. Through OHSL, he has pioneered initiatives such as virtual tumor boards, connecting oncologists from Africa to the U.S., and championed a team science model that accelerates discovery through open data and collective problem-solving.

From collaborating with the National Cancer Institute to advocating for the single-dose HPV vaccine now endorsed by the World Health Organization, Dr. Mehrotra offers an inside look at how global insights are reshaping prevention and access to care. Along the way, he and Colette unpack the ethical challenges of innovation—how to balance public good, profit, and purpose in a world increasingly driven by AI and data.

What You’ll Learn:

  • How open collaboration and informatics are transforming cancer research
  • The story behind the Open Health Systems Laboratory and its global mission
  • How virtual tumor boards are connecting oncologists worldwide
  • Why the single-dose HPV vaccine is a breakthrough in cancer prevention
  • How AI and data-driven learning are shaping the next generation of global health research
  • The ethical balance between innovation, access, and profit
  • Lessons for founders on patience, perseverance, and integrity in healthcare innovation

💡 Golden Nugget:

“Never pursue profit at the cost of causing harm. Do good—and success will follow.”

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