Dr. Scott Sherr | Methylene Blue & The Science Behind Health Optimization | September 12, 2025 Ep. 24 - The Low Carb Consultant

Episode Transcript
Available transcripts are automatically generated. Complete accuracy is not guaranteed.
(00:11):
All right guys, welcome back to the Low Carb Consultant podcast.
So today I'm excited to introduce Doctor Scott.
Sure, he is a board certified internal medicine physician who
focuses on health optimization medicine and integrative
hyperbaric oxygen therapy. So he serves as the COO of both
Smarter Not Harder and Transcriptions, the company

(00:33):
behind the innovative trophy supplements that boost
metabolism, brain function and resilience.
His work brings together telehealth, personalized
protocols, and cutting edge longevity tools to help people
heal and perform at the best. SO Doctor Scott, pleasure to
have you on man, and finally meet you.
Likewise, Max, happy to be here,yeah.

(00:55):
Absolutely. And like I was saying before we
recorded, I know there's lots oftalk online about methylene blue
and all of these different supplements in regards to human
optimization, performance optimization.
Definitely want to touch on a lot of that stuff as well as as
well as some of the I was doing some research on some of the
other supplements and protocols that transcriptions

(01:18):
transcriptions offer. So definitely want to dive into
all that. Maybe before we get into all of
that, could you give the listeners who just might not be
familiar with who you are quite yet, just a real brief
background on yourself and what took you down this specific
optimization pathway? Sure.
Yeah. I'll try to go with the short
story today. So I grew up the son of a

(01:39):
chiropractor. So I grew up pretty
alternatively outside the box. And that was my framework until
I went to college and then medical school.
I decided to go to thinking thatI could find a really cool way
to kind of bridge the gap between what was, you know, was
really just called alternative medicine.
At the time. There was no integrative
medicine. There was no functional
medicine. And that stuff really existed
when I was going to school. That was, it was nascent.
It was early, early days. And then I thought, well, I'll

(02:02):
go to medical school. I figured out how I figured out
how to be this really cool doctor that does everything that
can do conventional medicine, that can do alternative medicine
and then find a way to kind of marry it all together.
And so I ended up taking my fastest Rd. outside or out of
medical school and residency, doing my internal medicine
residency, which is the three-year program after four
years of medical school. And then from there, I kind of

(02:22):
gravitated towards looking at various tools and technologies
that were marrying both the alternative and the allopathic
world. And this particular technology
that I focused and specialized in for over a decade and more
now is hyperbaric oxygen therapy.
And so over that decade, I, I created a, what I called an
integrative approach to hyperbaric therapy that created

(02:42):
kind of a A7 or 8 sort of pillarprogram for people as they were
thinking about using hyperbaric therapy and how to kind of
contextualize it in, in, in their own personalized way, in
the sense of like, is it right? Is it something they should do
now, something they should do later to optimize things ahead
of time? And then throughout that time, I
was always sending people over to integrative functional kinds

(03:03):
of doctors to help do some foundational kinds of testing.
And then eventually I, I met a colleague in 2017 and doctor Ted
Archer Koso, who had started this thing called Health
optimization Medicine and Practice.
And it's a nonprofit organization at that point.
It was just early on his practice that he was actually
developing into a nonprofit. And then in 2017 we
operationalized it and made it anonprofit organization.

(03:24):
That is a framework that trains practitioners like me on how to
optimize the health of our patients and clients using a
foundational framework using things called like metabolomics
and epigenetics, gut immune system and, and more in a very
holistic framework. And so I use that as the
foundation of what I do now in in clinical practice.
I have my own concierge clinicalpractice just using that
framework. And then I consult with people

(03:46):
for hyperbaric medicine all overthe world, sometimes just in
hyperbaric medicine using an integrated framework without
that foundation of health optimization medicine.
But often times that's where I try to kind of lean people into
it depending on the situation. And so I've been doing that as
sort of a concierge health optimization medicine
practitioner since 2019, I wouldsay.
And then in 2020, we launched a company called Transcriptions

(04:08):
out of the nonprofit. This company called
Transcriptions was developed to help people right now while,
while they're on the longer pathof, of optimizing their health.
And many people know that it doesn't take a day or a week or
a month, often times to, to really rebuild and regenerate,
rejuvenate our health after 40 or 50 years of not feeling very
good or getting to the point, you know that you need help now.

(04:30):
And so Transcriptions developed to help people right now while
they're on the longer path of, of optimizing their health and
giving them help with energy, with focus, with sleep, with
stress, with immune system function and more.
And and it's all kind of, you know, all gravitates around my
clinical practice from the clinical practices that the
people that of that are transcriptions company.
You know, there's a number of uson that are practitioners in

(04:52):
that company that still run our own clinical practices.
Our nonprofit is the same thing.And they're all kind of goes
around how we see patients and really trying to help people in
as the most, you know, holistic way as, as possible.
Yeah. And so definitely sounds like
there's a multitude of differentcompanies at play here.
I just had a quick question in regards to hyperbaric oxygen
therapy. How specifically would you

(05:16):
consult with like a client on utilizing A protocol like that?
Sounds like that's something that they have to go into like a
center or a clinic to have done or that's not something unless
they have like the actual chamber at their house, right?
Like they wouldn't be able to dothat at their house.
So you could have hyperbaric chambers in clinics for sure.
And there's different types of hyperbaric chambers in clinics.
You can also have different hyperbaric chambers at your

(05:36):
house. People have hyperbaric
hyperbaric chamber chambers at their house all the time.
And I used to work as a, as a medical director of a number of
facilities in the Bay Area in California where I lived.
And I would see people that werecoming in and want to use the
medical grade chambers. And then over the years, I, I
met a guy kind of like a doctor house kind of guy actually.
And he would have phone calls with people all over the world
giving them sort of second opinions about their health and

(05:58):
then giving them additional advice like, why can't I do that
for hyperbaric therapy? And so I, I basically became and
still do have an online telemedicine hyperbaric
consulting practice where I talked to people all over the
world about how to optimize their hyperbaric experience,
their protocols, the tools, technologies, and other things
that they can use in addition with lab tests might be helpful.

(06:19):
The health optimization medicineframework is my preference, but
it, that's not always possible for people depending on where
they are and what they're doing,whether you know, what other
surveillance kinds of things might be helpful as they're
going through hyperbaric therapy, whether practitioners,
whether referrals might be helpful today.
Should they go see like a neurologic chiropractor?
Should they go see an acupuncturist or whatever,
depending on what the situation is?
And so I've done that. Yeah, that's, I've been doing

(06:40):
that a long time now since probably 2000, I don't know, 17
or 18 or something like that where I've been doing.
So before telemedicine became cool kind of thing.
And, and and that's, it was small for a while, but it's got,
it's grown, you know, significantly over the years
because I've been involved in hyperbaric medicine for as long
as I have. But but what I've always thought
of hyperbaric medicine, honestly, Max as as kind of like

(07:01):
a smokescreen for what I actually do, which is I try to
really optimize patients health.And that is not something that
happens overnight, as mentioned.And so, you know, when I'm
talking to people about hyperbaric therapy, I'm very
clear if I think that's not the right time for them to go into a
chamber. And it might be something where
it's better to optimize, you know, various biomarkers,
especially your capacity to makeenergy and detox from the energy

(07:23):
that we make before you go into a chamber and, and flood
yourself with a whole bunch of oxygen and cause a whole bunch
of oxidative stress or stress inthe system.
And so often times it's better to wait three or six months if
you don't have an acute reason to go in the chamber to make
sure you're pretty well optimized before you do a
protocol, unless you're already kind of very healthy and it's
not a big issue. But for the most part, for most
people, they do benefit from having that kind of window.

(07:45):
And, and the key really there isto understand that you're going
hyperbaric chamber, you're increasing amount of oxygen in
circulation. And so when you do that, you're
kind of revving up your body's capacity to try to make energy,
but it also Revs up your body's capacity to create something
called reactive oxygen species or the Ros or oxidative stress
free radicals, all kind of namesfor the same thing.
And so if your body doesn't havethe capacity to make energy,

(08:07):
well, because the mitochondria aren't working very well or your
body doesn't have the capacity to detox from the energy that
makes, because when you make energy, it's not like it's free.
You make you make carbon dioxideand water, but you also make
these reactive oxygen species and you need to antioxidants to,
to, to neutralize those. And so if you don't have enough
antioxidants around, you're going to feel crappy.
Sometimes it's just crappy for acouple days.
That's normal sometimes. But it shouldn't be for like 2

(08:29):
weeks of doing hyperbaric therapy is still feeling
terrible, right? And so my, my framework here is
like, let's, let's focus on the cellular side of things.
Let's focus on the cellular medicine aspect, focus on
mitochondrial function, optimizethat.
And then by doing that using this health optimization
medicine framework, then that's,you know, maybe three or six
months later, then that's when I'm going to put them in a
hyperbaric chamber. They're going to see the best

(08:50):
results. But the key really is to focus
on the mitochondria often times and then kind of build out from
there. And that's what I use with the
products and transcriptions. That's what I use it with my
health optimization medicine practice.
And then, you know, send people every which way across the world
to do different things to, to help the mitochondria work
better depending on the situation.
Yeah, very cool. And let's dive a little bit

(09:11):
deeper into that because I kind of want to get into how you
prescribe certain protocols based off the client and what
they're specifically looking to achieve.
I would imagine, maybe I'm off base here, I would imagine that
most of your clients consulting with you are probably high level
athletes. Would that be accurate?
No, actually I really have. I have a whole gamut of people

(09:31):
that I see, I see high level athletes, I see it's interesting
like when I first started my health optimization practice.
So it kind of maybe the evolution is this right?
So on the hyperbaric side, the majority of people that I still
see are coming in with conditions, they're coming in
with, with strokes, with traumatic brain injuries, with
surgical issues. But over the over the years, the

(09:53):
number of people that have come in for endurance, for athletics,
for performance has gone up significantly.
So it used to be like 95.5, then95% condition based and 5%
performance based. But now over the years it's
probably more like 5050, maybe like 6040 where 60% condition,
40% performance. So it's definitely changed a lot
over time. And then in, in the respect of,

(10:16):
you know, when I see sort of in my own, in my, in my health
optimization practice, it's actually about the same.
It's about 5050 where I see that50% people that are really more
on the performance side. And I think 50% of people that
really are more the, the health optimization.
Like, you know, they have chronic issues and then they,
they may not, but they're sort of on the place where they're,
they're kind of older and they may have other things going on.

(10:37):
So for a while I was working with biohackers and that was no
fun. You know, I do like biohackers
in general, but like the problemis that they wanted to do too
many things all at the same time.
And like it just it, it makes itvery difficult to know what's
working, what's not working if you're throwing 20 different
supplements at something just because you feel like something
looked cool on Instagram, you know?
And so the big problem out there, Max, is that like,

(10:59):
there's so many people talking heads out there that saying, you
need to take this for your sleepstack.
You need to take this. There's even somebody coming out
the book called protocols prettysoon.
And that I'm pretty angry about because I'm going to have to
deal with all that shit that comes from people saying I
followed the protocol in this book.
It didn't work for me. Shocking.
It wasn't you. It was the person who wrote the
protocol has never seen it, likehas never seen a patient in
their life. I'm not, you know, I'm not

(11:22):
trying to name names, but you probably know what I'm talking
about. And so.
OK, I, I, I can, I can name a name.
The first name that comes to mind are like the Brian Johnsons
of the world who are trying to live forever like that's.
I mean, well, the Brian's interesting, right?
Because I think what Brian is, is just kind of like a shock
factor for people, right? And I I think that's not a bad
thing in some ways, but if you try to follow his protocol, I

(11:43):
promise it won't go well for you.
I promise. Yeah, it's ridiculous.
And I've seen a number of peopletry and it doesn't go well.
And what I often like to say in corresponding is like, look, you
can do 90% of what he does and not spend the ridiculous amount
of money and you can still eat meat.
God damn it. Please still eat meat, you know,
because if you don't, it's not good for most people.

(12:04):
I just, unless you're like an anomaly, I don't work with
vegans in general as as a practitioner, this is very
difficult to optimize their vitamins, minerals, nutrients
and cofactors. It's just not possible unless
they're like having gigantic amounts of supplements.
We just not, we just not like evolutionary program to do it.
And so Brian, for example, has like, you know, 500 supplements
a day to try to compensate for not eating like a piece of meat,

(12:27):
right? Because he's worried about
something in it. You would think real quick, you
would think with all like with how smart that guy is and how
much money he spends and the amount of money he spends on the
team to have around him, you would think that like he would
actually incorporate some meat into his diet.
Knowing what we know about, likeyou said, the the evolution

(12:48):
behind how we're actually supposed to eat, you would think
that he would involve some meat in his diet.
I'm actually pretty surprised that he doesn't.
We'll see. I mean, he's always changing
things, right? Like just and see, my sense of
it is that he thinks he can outsmart nature, which is
bullshit. You can't right?
And and like, and, and that's just the, the nature of the
human form, right? We also like in where we used to
like the, what was the headline back in the in the 1960s and

(13:12):
70s? It was, it was basically that
something, you know, we were going to live through chemistry.
Like we're eating through chemistry.
Everything is that was during the space race and everything
was like NASA based and you haveplastic meals and you had
microwaves and like we're livingin this like, you know,
chemistry induced utopia, which we know is now bullshit, right?
And so, but I, I used to watch the Jetsons as a kid.
I wanted, I wanted my own littlespace car and, and things and it

(13:34):
seemed cool, but it, it's not cool, right?
Because if you go to Mars on a, on a rocket ship, like you're
not going to do very well as a human, right?
We know humans cannot do these things very well.
You probably need more meat, to be honest, but I mean more than
probably better sunlight and, and better radiation production
and all those kinds of things. But that being a side, I, I
think that what you find with a lot of people now is that, you

(13:55):
know, they, they go online and they, they find that there's a
cool supplement, there's a cool technology and like, and they
have no like framework to how touse all that stuff.
And so the way that I like to kind of, you know, take a 30,000
foot view, that meta view is like, well, let's have a
framework where all that kind ofsits in rather than just like
going to look at the new squirrel that climbed up the
tree, your favorite influencer. And not to say people don't have

(14:19):
good things to say. I have friends that are really
great educators on there as well.
So, and I think that's important, but you know, for me,
it's always about this sort of ecosystem that you can create
for your patients. And, and then then everything
else gets a lot easier to to manage.
And so that's what health optimization medicine is.
It's, it's, it's a framework. And then it really looks at that
cellular side of things like from like the micro scale and

(14:40):
not yeah, and then and but not just looking at numbers, but
that's a big part of it. But then taking it from there
and saying, OK, are you getting sun?
Are you, what's your toxic exposure like?
What's your stress like? What's your, what are your
relationships like? And then looking at all that in,
in this sort of totality, right.And, and one of the totalities
I've been talking about a lot lately that I think resonated
resonates with me and also a lotof my my patients is something

(15:02):
that I call like this. It's called the sympathetic
spiral of doom, which is something that I've I've been, I
need some music afterwards. Go Dun, Dun, Dun.
You know, like it sounds dangerous, but, and it is right,
like basically we're stuck in this sort of, but our nervous
system is stuck in fight or flight, stuck in activation
mode, doesn't matter, shut off. And then as a result of that, we
deplete neurotransmitters, we deplete hormones, we screw up

(15:22):
our mitochondria that are tryingto make more energy, but they
can't after time. And you get this sort of
perpetual cycle and spiral wherethen the mitochondria aren't
making much, much energy. And then as a result of that,
you're trying to spit out more stress hormones to compensate.
And then you can just, you know,you crash at some point, like it
happens to almost everybody that's in sympathetic overload.
So. So I don't remember your
question, but that's the answer to.
It no, no worries at all becausewhere I wanted to go next is

(15:45):
maybe diving into specific protocols based off of who
you're working with and what they're ultimately looking for
how do you decide the first thing to target for a client
wanting faster recovery metabolic gains whatever the
case is how do you go about thatwell it.
Depends on the person and kind of where they're starting from
and where they want to go. And then are we going to be able

(16:05):
to do like lab work? Are we going to be able to have
time to be able to kind of create a plan for somebody or is
it somebody that needs somethingtomorrow?
Obviously the the better situation is somebody that has
time to plan what's going on andthen you can create a plan that
can help them long term and thenshort term help support that
plan as they go. That's the more ideal situation,

(16:25):
right? But the, the key really is that
for everybody, like the basics are the basics for a reason.
Like they're important for everybody, right?
We have to have the basics at play.
The basics are not basic. They're not easy, but they're
basic is what it comes down to. Because, you know, eating well,
moving well, you know, drinking enough fluids, hydrating or
hydrating, getting enough sun and getting enough sleep, like

(16:47):
these are like the basic things that all of us need, but very
difficult for some of us to really fully encompass all the
time, right? And so when I'm working with
somebody, I really have to understand what their goals are.
But at the same time, I, my perspective on health with the
health optimization framework islike, well, that's, I need to
know those goals. But to get those goals really to

(17:09):
be accomplished, we got to get afoundation for you to start off
with. So I use something called
metabolomic testing, which is the study of how our cells are
working in real time. And it takes environmental
inputs, it takes inputs from your cells and look at all these
things real time. It's happening right now.
And then from there you're able to kind of build a profile of
what somebody requires from the vitamins, minerals, nutrients

(17:31):
and cofactors perspective. If they have heavy metal
toxicity, if they need differentfatty acid profiles, you can
work on all that. That takes time.
And then I look at somebody'd gut as well.
I'm looking at the gut microbiota, looking at and also
looking at signs of things like gut inflammation, leaky gut,
digestive issues is those are really important.
And then with all that data, I, I create a health optimization

(17:52):
plan for patients that's kind ofa basic foundational one.
And then to get them from point A to point, you know, Z or
whatever that, you know, whatever the, there's really no
final point. But you know, as we keep going,
it's like, it's like the, it's like π right.
It starts off and never good. There's never an ending for π
it's just like life until, you know, I guess you die.
But, but the goal really is the path, as I'd like to say.

(18:14):
But in the beginning, many people didn't need more support.
And so some things that I'll think about using, for example,
especially if there's like needed like a lot of
mitochondrial support, we something like methylene blue,
which is a great compound. It's been around for a long time
and helps support mitochondrial function.
And so if you need some additional support, it's a great
way to do that. If you need some stress
mitigation mitigation, it's really important to break that

(18:35):
spiral of doom that I was talking about before.
And that really, and that reallyactually makes the most sense to
address the GABA system. The GABA is our main
neurotransmitter, our brain thatkind of calms down firing.
Very cool. OK.
And I definitely want to talk about methylene blue here in a
quick second, but something kindof popped up into my mind here.
Do you ever get the sense when you're dealing with a client and

(18:56):
you're recommending like multiple protocols?
Like is there ever a sense wherethey're just a little bit
overwhelmed by all the things that they feel like they need to
do? Or do you sometimes we'll just
condense it and say this one thing right here is just do this
and this is going to get you thebiggest thing for the buck.
And maybe that is methylene blue.
I was just curious if you ever run into that and then you just

(19:17):
say, hey, just do this. Well, my high performance
athletes will do almost anythingyou tell them to do, right?
They're very good at following protocols typically.
And so you tell them to change 10 different things, they'll
change 10 different things. But those are the exceptions to
the rule. Most people have a hard time,
you know, changing their stuff, you know, And So what I often do

(19:38):
is I try to give them the long term view as much as I can.
And then we do it in a stepwise fashion depending on what's the
most important thing to address at that moment.
So if it's the gut, we address the gut first.
If it's hormones, we address thehormones first.
Whatever it might be, usually it's the gut For me.
Usually when I'm working with people, the first thing that I
address, if I can't address everything at the same time
because it's just too much will be their GI system and

(20:00):
optimizing that because if you can get better digestion, better
optimized commensal bacteria. You know, less inflammation in
the gut and, and Leslie don't have a leaky gut anymore.
You're going to feel a whole lotbetter.
But I, I, but I give people bread crumbs along the way.
Max, that's the key. Like you can't just say you're
going to feel better in three months or six months or a year
because nobody's going to stick around with you.

(20:20):
If I tell you they're going to have bloating and diarrhea every
five days for the next two weeks, that's kind of doable.
If I say it might be 3 months orsix months until you feel
better, that's a little bit longer, right?
So I go to like, what can I do? I can give them make sure
they're having bowel movements every day.
If I think they're going to go through detox, make sure they
have an infrared zone or are they get into like get someplace
hot, they live in Austin, just get the hell outside for a

(20:41):
couple hours, you know, during the week or something.
And then I also think about, youknow, various, you know,
interventions from a supplementation perspective to
help them now while they're on that, that longer path.
And I think that's the key is like, I try to get people the
longer view, like, look, this isgoing to take some time, but
this is this is how we're going to get you there.
And then I also will stagger protocols as much as I feel like

(21:03):
it's necessary to kind of roll out things rather than all at
once. I also, I also have to have a
very kind of frank conversation with people to understand how
much stress and lifestyle, the shifts they're going to be able
to make. Because I have to be very clear
with people, if they're not, if they're like in that, that
sympathetic spiral of doom, it doesn't matter how many

(21:23):
supplements I give you, doesn't matter how much we change your,
you know, fill in the blank, nothing's going to change.
I promise you. Not very much at least.
And so there has to be a way to,to address those kinds of things
and they have to be ready to do it.
Like I've, I've had people that I've spoken to on the phone,
like with consults, I can tell right away that they are so
sympathetically dominant that there's nothing that's going to

(21:45):
change physiologically until that stress comes down, right.
And so you can't just get rid ofthe stress and everything's
going to be better. That doesn't work either because
like there's been a big movementover the last several years of
just dealing with your trauma. And I don't mean that in a, in a
quip sort of way, like just dealing with the trauma.
Like, no, that's that's a big deal to deal with trauma,
whether it be, you know, sexual abuse when you were a child or,

(22:06):
you know, marital abuse or, or even like a traumatic
hospitalization or whatever. These things can be traumatic
and people need to work through them.
But the problem is just working through that side of it is not
enough because you already have that spiral ongoing that
mitochondria that are not working very well.
And, you know, those mitochondria are important.
Yeah. Like you have tons of
mitochondria in the body. Like in 7th grade, we learned

(22:27):
that you had a mitochondria in your cell.
But like in some places, we havethousands of mitochondria per
cell in your sperm, eggs, brain,thousands of mitochondria per
cell as opposed to in your heartand your liver.
You have other cells that don't have as many.
But like those are your energy engines.
And if they're not working very well, like you're not going to
feel well. And so no matter how much stress
you mitigate, if the mitochondria is still under

(22:47):
significant amounts of stress orthe word would be deficient in
various types of things that require it to make energy
effectively or detox, you're notgoing to feel good no matter how
much stress you mitigate. So in the end, the long answer
to your question was that the short answer is you have to meet
people where they are and give them bread crumbs along the way

(23:08):
to get them where you you know where they want to go.
Yeah, yeah. It what kind of popped into my
mind too. It's like kind of solving a math
equation, right? There's an order of operations.
That order of operations might be a mile long, but it's like
you got to attack one thing and knock it down and then kind of
move through and every and again, everyone's order of
operations is going to be slightly different based off
what they're trying to achieve. But that's what kind of makes

(23:29):
sense to me is like building it out and then tacking one thing
at a time. And that's how people probably
going to become the most successful.
But I was curious in regards to all these different protocols,
right, like hyperbaric oxygen therapy, peptides and methylene
blue, you know, if you could recommend one for a client and I
know you probably that's that might be hard for you to do

(23:51):
based. Off like the circumstance.
But but it would there, what would there be one thing like
OK, like if it if I had to pick one, this is the one thing that
I would recommend most people maybe either supplement with or
implement into their protocol toget the biggest bang for the
buck in regards to mitochondrialhealth, human optimization,
longevity, all those types of things.

(24:12):
The one thing, man, you want me to tell you one thing?
Well, shit. If you had to pick one.
I mean, if I had to pick one, itwould either be something that
was, we would be focused on thatsympathetic spiral of doom,
either breaking sympathetic fight or flight or supporting
mitochondrial function. But I often choose the

(24:33):
mitochondrial function first because again, if you break the
fight or flight and you don't, you still have mitochondrial
dysfunction, you're still going to feel terrible.
And so I, I, you know, it's one of those things where if I had
to choose between those two, I would pick the stress side of
things almost hands down, right.If you, just because like, if
you can, if you can break stress, everything else is going

(24:53):
to get easier. It's not going to like, you
know, be sunshine and rainbows, but it's, it's going to be
easier if you can break that stress, stressful spiral.
So like, for example, I know within, I mean, sometimes it's 5
seconds, sometimes it's 3 minutes.
But I know within that time frame after talking to somebody
on the phone or on a zoom call for a, a, a consult, whether the
tools and technologies and practices and things that I do

(25:14):
is going to be be able to help them or not.
And, and, and, and this is not to say that I'm always the, the
right judge of this. I've just been doing it long
enough to know that if I can just kind of tell that no matter
what I do, nothing's going to change unless they fix, they
fix. They just address what, you
know, the sympathetic spiral is,is, is, is ongoing for what the

(25:35):
reason is, if there is a reason kind of thing.
And so it's and it's, it's one of those things like I remember
a story recently, I was talking to a lady.
She I think she'd consulted withme about hyperbaric therapy.
She wanted to know about methylene blue.
And she was just telling me about all these things that she
tried, all these doctors that she tried and that she wasn't
sleeping and that and I get her kids were sick and then she had
to do this. I'm like, well, I think we got
to take a step back here, right?You know, so if, if I don't

(25:57):
think nothing blue or hyperbarictherapy is gonna be healthy
here, I think that you really think about like, what are these
sort of patterns that you've created and how you, how we can,
how can you address them so thatyou're not having this
sympathetic spiral where you're just continuing stressing the
system and don't have any downtime because The thing is
like in. Yeah, like it sounds like to me,
like her, her, her, her living situation or her home situation

(26:18):
might just be an absolute shit show causing all of this stress,
anxiety, whatever the case is. And you don't know this.
So The thing is that the chickenand the egg is difficult to know
sometimes, right? Because you can have like a good
example is COVID, for example. So if you have if you got severe
COVID and then you get severe mitochondrial dysfunction
because of that, which has happened.
And I have a number of patients that I work with over the years
like this. You may not, may not have had

(26:40):
any kind of stress at all related like sort of sympathetic
activation because of an issue related to COVID itself.
It was just you had the mitochondrial dysfunction that
happened because of the infection.
And then the mitochondria get dysfunctional and the system
gets in this sort of reactive state, like shit, you're not
making enough energy. So we need to like put you in
stress mode so you can make moreenergy, right?

(27:00):
And then as a result of that, you get the sympathetic
activation because of the mitochondrial dysfunction.
So that's why it's really important to, to kind of really
suss that out. And then if you can find out
what kind of, if you can figure out the chicken before the egg,
which again, sometimes hard to do, sometimes it's pretty
obvious, then you can kind of, you know, either focus on the
chicken or the egg. But most of the time I have to,
I focus on both at the same time.
So I mean, my, you know, it could be the one intervention

(27:23):
could be like divorcing your spouse, we're getting in or
sleeping in a new bedroom. Then your spouse, if there's no
way or it could be, I mean, every, all the interventions are
going to be different, but they're going to be sort of
related to those two categories,either stress breaking that
spiral or the mitochondrial support aspect.
And then, you know, then I have products that I use, of course,
to help with this stuff to get people feeling better very fast,
so they can feel what it feels like to not feel stress or to

(27:44):
feel what it feels like to actually have mitochondrial
support. And by doing that, you give them
an, a window into opening up like, oh, where things are,
things could be actually different than they can actually
feel. And then that's when you have
more of a window to do some of the harder work sometimes.
Yeah, very cool. And that makes sense.
I wanted to pivot real quick to methylene blue.
So looking into it a little bit and I understand it was like a

(28:07):
textile dye or a fabric dye and people online are calling it a
limitless pill. I'm, I'm curious to get just
like maybe a brief background onmethylene blue and then then we
can kind of dive into like how we can use it for optimization
or whatever the case is. Sure, sure.
So Blue Man Group, everybody seems Blue Man Group.

(28:27):
I'm just getting. So no, we're not painting
everybody with blue this these days.
But the, the idea was back in the 1870s, they were creating
these textiles to make various colors and they found this one
that they developed called methylene blue that dyed things
shockingly blue. And so in the 1870s, it was the
preferred pigment to dye blue jeans blue, for example.
But they were also looking for drugs or compounds really.

(28:50):
Basically, they have drugs at the time, compounds that would
actually help with infection because there was very few
available. There weren't any real
prescribed antimicrobials until after World War 2 until the 19,
the 1940s and 50s. And so before that, they were
doing all these studies on various compounds and they were
studying the type of dye, thyzine dyes that nothing
belongs to. And they figured out that

(29:11):
methylene blue had this amazing capacity to kill pathogens, not
only to kill pathogens, but to actually not harm the human host
after killing pathogens, even athigh doses, which was a very
novel thing. They did find certain things out
there in the world that would kill pathogens but also kill the
host. But that's not very helpful as
we all know. And so this was an exception.
That's why it called actually the name of the magic bullet at

(29:33):
the time because it had its capacity.
So between 1897 when it was the first drug registered with the
FDA for malaria, actually at thetime until 1950s, it was the one
of the primary antimicrobials around.
Even during World War 2 was something was used like in the
battlefields if people in the Pacific, they had to use it
prophylactically at higher doses, about a milligram per
kilogram or higher. It's a fantastic antimicrobial

(29:55):
is what it comes down to, has noreal resistance patterns
compared to other antimicrobialsthat have come around since that
time. It does have a couple side
effects that make it less exciting for people to use,
including blue urine, blue urine.
If you take methylene blue, yoururine will turn blue.
That is just something you should need to know.
Yeah, Yeah. And so it just because the
methylene blue concentrates in the urine and so you're going to

(30:16):
urinate blue if you if you take very high doses of methylene
blue, actually some of your other secretions like your poop
and your tears and things like that, but that's only like a lot
of methylene blue over about 3 milligrams per kilogram.
Subsequently, that's actually the doses that might turn your
brain blue. And there was a whole thing
about blue brains that came out maybe about 3, about 5 or 6
months ago now where there was people saying like, if you take

(30:37):
methylene blue, you're going to get a blue brain and it's going
to stay there. And the answer is no, that's not
going to happen, especially at low doses, at very high doses,
give an IV that may happen, but the high doses IV are only given
at very, very shocking times like CPR, cardio, pulmonary
arrest, septic shock, vasogenic shock, these kinds of things.
And so, but lower doses of nothing blue are very safe.

(30:58):
And, and the reason why all thisis sort of kind of evolved into
that is that because nothing booze got a different, a couple
different, you know, chapters after the one of being
antimicrobial, the next was as the first, it was actually the
drug that the first antipsychotics were derived
from. It has capacity to increase a
couple neurotransmitters, ones like neuronephrine,

(31:19):
neurapinephrine, dopamine and serotonin, for example.
Those are all increased with methylene blue because it works
as something called a monomine octodase inhibitor.
It also became a laboratory stain.
And so that's how I learned about it in chemistry class when
I was in college. But interestingly, So what is it
stain? What is it we use it for in the
cell, we actually see it concentrate in the mitochondria.

(31:39):
So over the last couple of decades, there's been a lot of
interest in methylene blue and how we can support mitochondrial
function. And that's really where my
interest and the interest of my company really came in.
In like 2018 time frame, knowingthat there was some studies
showing that methylene blue had the capacity to increase memory,
verbal processing, cognition in healthy adults.

(32:00):
And also there was some, there was some preclinical stuff in
animals showing significant benefit in things like
Alzheimer's, concussion, traumatic traumatic brain
injury, potentially in Ms., Parkinson's disease and a couple
other things as well at lower doses of nothing like 5-10, 15
milligrams of methylene blue, 16milligrams of methylene, but not

(32:21):
super high doses. And so we decided to make a
company that developed a number of products that help people
right now as I was leading to earlier.
And the first company, first product that our company made
was one that contained methyleneblue.
This is in 2020, we launched andwe were the first company to
develop and release a commercialized methylene blue

(32:41):
product at that time. Now Fast forward five years
later, there's about 60 different companies making
things of methylene blue in them.
So the it's got a little bit crazy and that's OK.
It's been a lot got a lot of popular opinion, popular people
talking about it the last year or so.
And it's obviously been good forbusiness on our end.
But but waiting the there's, it's a bit difficult to navigate

(33:02):
as a consumer. There's a lot of nothing but out
there. You have to be super careful of
contamination. It can get contaminated with
heavy metals like lead, mercury,cadmium and arsenic, which you
don't want. A lot of the liquids out there
are also very low in potency compared to what they say on the
label. So it might say, you know, it's,
it's like it's 1 milligram per drop or something like that, but

(33:22):
it ends up being like .4kg per drop.
Like it's super low concentration often times when
we've tested them. So, yeah.
So the short story with how we use nothing to now he does a
mitochondrial support. It helps with energy production
and helps with detoxification. It can compensate for any
element of mitochondrial dysfunction and when you're
coming to the the process of making energy and help with the

(33:45):
any element of helping the detoxification side.
So what I tell my patients all the time, it's energy and detox
or energy and resilience. That's what Methylene Book can
do. Very cool let's let's let's go
deeper then so they're in the form of like lozenges or like
trochis, correct, correct yes and that's how we.
Can make descriptions? Yep.
Yep. OK, perfect.
And then I'm, I'm, I'm assuming there might be different

(34:07):
strengths in regards to the lozenge that that you're
ingesting or sucking on or whatever.
Let's say I pop the lozenge. What would be like the top three
things I would notice right out of the gate?
Really depends on the person, right?
Because I think a lot of people are using methane blue for
different reasons. If you're using it for endurance
or performance or if you're on your health optimization journey
and you're starting really slow and don't have a lot of energy

(34:28):
and have a lot of detox issues, you might see some benefit on
that side too. So a lot of it depends on kind
of where you're starting. And often it really depends on
the dosing as well. And so, but in general, most
people feel is an elevation, a better mood, a little more
energy, a little more capacity. Depending on the dose, it might
be a lot more capacity, a lot more, a lot more energy, but

(34:49):
it's really, it's not typically feeling like you're on Adderall,
for example. Like Adderall is a stimulant.
Methylene blue itself is not technically a stimulant.
It does have some properties that can make you think it might
have similar effects, but not the same.
Excuse me, not the same degree as taking an Adderall.
For example. There are rare people that take
methylene blue and feel that way, but for the most part, it's

(35:11):
not typically that feel. So usually you'll feel that you
have more staying power, you have more brain power, you have
more endurance for a longer period of time and.
These are effects I would noticewithin minutes.
Wow within about depending on how you take it, if you take as
a buckle trochi like which is how we develop them and develop
them at transcriptions. So trophies are these
dissolvable lozenges that go between your upper cheek and
gum. What's nice about a trochi is

(35:32):
that, and this is what all of our products are developed like
at transcriptions is that we have the dissolving here between
our boutique and gum because it's faster.
So you have faster acting usually within about 15 to 30
minutes as opposed if you swallow something, it can take
45 minutes, an hour or longer depending on the situation,
especially if you're not fasted.The nice thing also about a
buckle trochi is that you can have more powerful ingredients

(35:55):
because when you swallow something, it goes through
digestion in your stomach, your liver, etcetera.
That's called first pass metabolism.
You have a degradation of those ingredients.
Often times nothing was actuallyan exception, which I'll talk
about in a minute, but it's niceto have as a buccal trochy for
the most part for many ingredients because they don't
get degraded in the liver. The third thing that's nice
about them is that titratable. So you can start off the trochis

(36:17):
are developed as these square lozenges and they have a like a
line in the middle of it across.So you can cut it up into a
quarter, half or full, dependingwhat you need.
And then you can kind of dial inyour dose.
OK. And so it takes about, yeah, as
a trochy about 15 to 30 minutes to start working.
But the thing about methylene blue, as I mentioned earlier, is
that it's it's shockingly blue, this particular compound.

(36:38):
And so if you dissolve the mouth, your mouth is going to
turn blue. And and not everybody wants a
blue mouth. I totally get that.
So if you're going to have it and not dissolve in the mouth,
the second best is to swallow iton an empty stomach.
If you swallow on an empty stomach, it'll be faster than if
you have it up with food, for sure not as fast as dissolving
in the mouth, but your mouth won't be blue in the process,
which got it. Not everybody wants a blue

(37:00):
mouth. But if you do have more
cognitive issues, more mental health issues, sometimes
dissolving in the mouth is actually better because it's
going to work faster that way. But the, the, the key is
everybody's a little bit different.
So like, for example, if I'm working with my endurance
athletes, well, they all tend tonotice when they take methylene
blue is that they can keep theirheart rate up for longer without
having to slow down. And the reason for that is that

(37:21):
methylene blue can act just likeoxygen in the mitochondria in
those cells, in the energy partsof our cells, energy producing
parts of our cells. And it's so it can simulate
there being more oxygen around for longer than there actually
is. And so you can see the potential
additional benefits of this is if you're going on an airplane,
for example, if you fly long distance or go on any airplane

(37:41):
really, you're being pressurizedto between 6008 thousand feet
above sea level. Every cabin is pressurized.
And if you live at sea level, you're at 21% oxygen.
But if you get on an airplane and you're pressurized to 8000
feet, you're about 16% oxygen. So that's a lot less oxygen that
you're getting in all of a sudden.
And so the body gets into this sort of stress mode immediately.

(38:01):
It also gets tired as well. This is one of the reasons why
as soon as the cabin door closeson an airplane, you start
feeling tired is because you're suddenly at 8000 feet, you know,
from zero, you know, And so that's a big deal.
So methylene blue can compensatefor that by coming into the
mitochondria to really start helping you make more energy
more effectively and compensate for that low oxygen state.
And so if you're an endurance racer, you're going to feel
that. If you're on an airplane, you're

(38:22):
going to feel that. If you are on a mountain, you're
going to feel that. So if you're mountaineering,
you're going up high peaks, you have to stop because you don't
have enough oxygen capacity. The oxygen levels are lower when
you're on an altitude. And so you can't go as fast for
as long as you want and nothing but can help with that.
And so we're actually doing sometrials now and, and working with

(38:44):
a couple people to try to get a sense of of that better.
But we have one cyclist that is not telling anybody that he's
using it. He doesn't want anybody to know
because he doesn't want anybody to know why he's doing better
with all his times. And it's legal.
It's not something that's it's water approved.
It's not something that's going to be illegal if you get caught
with it in your urine. The only thing is that, you
know, if you're taking pee testsand your urine's blue, it's

(39:07):
going to be surprising to the people that you're working or
the people that are that are checking your urine kind of
thing. And it can also potentially mess
up some of the other analytes I've heard before as well.
And they're looking for other things.
But but itself is not an issue when it comes to drug testing
for water improvement status andthings like that.
So from so for my athletes, that's often endurance.

(39:28):
It's, it's also, and, and then there's also the other piece
where we think that there's actually some pretty good
studies on methylene blue in animals and dogs by of
increasing lactate threshold. So you time to lactate
threshold, your time to lactate buildup is longer, so you can do
more work, do more exercise. And that's kind of dealing with

(39:49):
what I talked about, which is that aerobic capacity going up
as I just mentioned, which is why this is the case.
And then there's also some indication that maybe you can
actually recover at a higher heart rate with methylene blue
around because again, that the capacity of it to, to work on
energy production, detoxification.
And so that you'll find that youdon't have to be as at a low of

(40:09):
a heart rate to feel like you'reactually recovered when you have
nothing blue around. And that's at least anecdotally
so. I also have a friend of mine,
big guy in the CrossFit community for many years.
His name is Brian McKenzie, who you've probably heard of.
Brian's also been playing aroundwith a lot of hypoxic training
along with methylene blue and seeing that if you do hypoxic
training ahead of time and then you do aerobic work afterwards,

(40:31):
you have significant benefits aswell and increasing VO2 Max and
things like that when he does it.
So there's a lot of different ways.
And then on the other side of the spectrum, if you're, if
you're, if you're dealing more of like with a chronic issue, I
mean, it could be almost anything.
But like the way that you'll start feeling better, a little
bit more energy, a little more detox, like you feel like you're
actually your brain's better on like your brain fog is better.
Maybe your anxiety gets better, your mental health problems get

(40:53):
better, like to some degree justbecause your mitochondria are
getting more energy, right. And so I like to think of
methylene blue at low doses like481216, kind of being like an
adaptogen for these kinds of people where if they need more
energy, that's where it's going to start.
If they need more detox, that's where it's going to start.
And then it's going to start helping the system rebuild
itself and rejuvenate as a result of supporting the system
and where it's required. Man, that's so cool.

(41:17):
And it kind of makes me think back to when we had the gym out
in Las Vegas when we were like sending teams to regionals and
stuff like that. So we were in the like the
Mountain West region, but guys would have to go up to like Utah
or higher elevations to ultimately compete.
But that would destroy people. And we would see a lot of the
times the people that were in Southern California that would

(41:38):
come up and work out even just being in Las Vegas.
It's just a, it's not like a crazy elevation from sea level,
but it's, it's enough to where you would, you would notice
that's it. So if you have people from
Southern California or sea levelcoming up and to train in Vegas,
they would be getting crushed bycertain workouts.
And then if you're going up to like Denver, Co to work out,
then you're getting really crushed.

(41:58):
So it's like, man, I wish something like this was around
years ago. To be able to compete at these
higher elevations like that would be a very useful tool.
That's why people like people that live where I live are at a
significant advantage. And that's why, yeah, a lot of
the ultra marathon, marathon high performance communities,
they live in these areas. What's funny enough is that they

(42:19):
don't take care of themselves. Like they just run until they
can't run anymore because they're not actually minding
their mitochondria at all and minding their oxidative stress
levels, which get gigantic. And This is why you see people
with like, you know, calcified, you know, arteries and have to
get triple bypasses that that are 50 that have been doing
ultra marathons for for 20 years, right, Because it's a lot
of stress on the body. And so that's why supporting

(42:39):
mitochondrial function so important.
And also, you know, not just on the energy side of the detox
side too. And again, it's a lot of stress
on the system. It just has a kind of a side
note for people. But but yeah, I mean, that's
that's in essence where, I mean,I've just seen amazing stories
over the years with methylene blue, right?
And that's why I've gotten a lotof healthy respect for it.
It's not the one thing like you were asking me before and I was

(42:59):
hedging on this is like the one thing that anybody could do
because it's like it's so variable depending on the
person. But it is something that I
almost always will recommend in people to start off at low doses
as they're building up their system if they have a long way
to go or if they're trying to tweak and optimize their system
on the other edge of performance.
Because on both edges, the performance edges is a knife's

(43:22):
edge too. And people on that side are
often very close to burning in some way because especially if
they're, you know, an older athlete, if they're over 25 or
30 years of age, like then they start breaking down.
This is when they start getting injuries and like, oh, I just
got injured. Like, no, it's like you're
causing so much oxidative stressand in your body for such a long
time that, you know, eventually things just sort of crashed,
right? But like, didn't happen
overnight. You know, this has been going on

(43:43):
for a while and the system just couldn't tolerate it anymore.
So I think the, the key for people that are listening is
that I understand that's very important to that methylene blue
is a fantastic mitochondrial support.
So it'd help with energy to helpwith detox and help you go
further and go higher and for longer because it can work just
like oxygen as well. And that mitochondrial
dysfunction is not just for people, you know, on the sort of

(44:04):
the complex medical illness side, which it is like you're
long COVID, chronic chronic autoimmune problems, chronic
fatigue, fibromyalgia, of course, but also on the
endurance side. You guys are always on the
knife's edge of just, you know, getting injured, probably
because you're not recovering well enough.
You're not down regulating that nervous system, you know,
because that down regulation, that other nervous systems
called your parasympathetic nervous system.

(44:26):
And that's when we rest, digest,detox and actually build muscle
and gain muscle. So you don't gain muscle being
sympathetic all the time. So if you're out there running
and racing and you're not feel like you're making any gains
probably as you're doing too much, not too little, often
times, right? And so we know that ramping down
exercise can be dramatically helpful for a lot of people in
these kinds of situations. So just some things to to think

(44:47):
about. No, no, that's, that's, that's
great advice there. And that obviously makes a lot
of sense. One thing I wanted to touch on
with you because I'm seeing a lot of comments online just
about hyperbaric oxygen therapy,methylene blue and some of these
different biohacking type of interventions and people saying,
oh, you know what, like this is for P.

(45:07):
And going back to like the BrianJohnson thing, these
interventions and protocols, they're just for people that
have money or they're just for people that can afford them.
What would you say to critics that are that that say, hey,
these types of protocols or interventions are only meant for
people with certain financial means?
I mean, the first thing is that the best things in life for
Freeman, right? You know, go outside, go, go, go

(45:29):
ground yourself, you know, get drink.
I mean, hydration doesn't cost that much money.
Eating, you know, doesn't have to cost that much if you do it
right. You don't have to go and get the
most artisan stuff ever to do it.
So I think the basics like sleep, stress, like these are
all things that don't cost a lotof money typically and that are
very important as basics, right?And I mentioned this earlier

(45:49):
where you want to get people a road map to where they want to
go. But it does require, you know,
some bread crumbs along the way to help them understand that,
you know, if they want to feel better, they have to stop eating
pizza twice a week or whatever it might be.
And they have to be willing to do those kinds of things.
But, you know, it's about where they are and like how you're
going to get them there sometimes, right?
And so I think that the low hanging fruit is the stuff
that's for free or close to it. And then like above that, like,

(46:13):
well, how are you going to kind of, you know, help with those
bread crumbs along the way? And things like methylene blue
are not that expensive to try assomething as to support a very
unnatural world that we live in a very synthetic world that we
live in, right? We don't live in the Jetsons
yet. But I mean, that's the idea.
We don't live in a a natural ancestral world anymore.
So we need sometimes things thatare not from the natural world,

(46:35):
like methylene blue is a synthetic ingredient to actually
help us and, and help our mitochondria work better.
And so I think when it comes down to it, for me, when I'm
working with people, it's let's get the basics together, but
knowing that the basics are not easy, OK.
And so then what are those sort of what's the lowest hanging
fruit that we can use on top of the basic things that we all

(46:57):
need to be doing to help get people to do the basics better,
You know, and then that could befrom getting a meditation device
or, you know, starting to do a breath work practice or starting
to do 10 push ups a day or one push up a day.
I don't give a shit. Sometimes it just means it's
just one push up. That's fine.
Like whatever that sort of habitthat's going to be, that's going
to start changing everything else that you do, right?

(47:18):
And so, you know, we've exerciseis something called the
cornerstone habit, right? You start exercising, typically
everything else gets easier. You want to eat better, you want
to sleep better, you want to have better relationships, your
moods are better, right? And so that's great.
But not everybody can go exercise right away.
So what's the corner of the stone habit for each individual?
It's going to be different, right?
But but I found to be the biggest lever there, the biggest

(47:39):
2 levers are energy and stressing less.
OK, So if you can make them feelmore energy, even if they're
overstressed and everything else, but they sell a little
more energy like, OK, then they start feeling a little bit
better, then you can start doingother stuff like, or if like if
you can just down regulate a stress response a little bit
with some support and and some guidance.
And that's really important because if people have been
stressed for long periods of time, they don't even know what

(48:02):
it feels like to have a down regulated stress response.
And then that's going to be a setup for having reactive
anxiety when you actually decrease their stress.
And I've seen this like we have some things that our company,
something called Trocom, for example, transcriptions that's
graded down regulating the nervous system.
But I've seen it in front of me,somebody have an anxiety attack
once their stress less level went down so low, they didn't

(48:23):
know. They didn't know what it felt
like to be that way anymore. So they'd reactive anxiety
related to that, you know. And so yeah, yeah, totally.
It happens all the time because people don't know what it feels
like to be down regulated like that, right.
And so my, I guess as I kind of talk about this, it's sort of
give people the experience of what it feels like to feel like
they did before, you know, in quotes, right?

(48:44):
Like this is how it used to feelwhen you had more energy.
This is how you used to feel when you had less stress.
OK, that's how it feels. Let's go back there.
Like that's how we can get thereover the long term by optimizing
your diet, your labs, your, yourrelationships, your stress, all
that kind of thing, right. And so finding a way in my ways
in or the mitochondria and then the, the stress system that

(49:05):
breaking that sympathetic spiralof doom.
Because if I do them at the sametime in a, in a sort of a
Symphony of I conduct the Symphony in a way that they can
feel both at the same time. That's really where I found the
the best outcomes and patients where they can really see that
there's a light at the end of the tunnel or that there's
there's just a light in general.Like there's something that's

(49:26):
not just darkness or like I can't break this kind of deal.
Or if you're like an athlete, it's like I can't, I can't do
anymore. Like I'm done.
Like this is as much as I can do.
I'm starting to break down or like I just can't increase my
times or decrease my times or whatever it might be.
Like I'm stuck. Like the stuck part of it is
like there are ways around that or through it, but it's not

(49:46):
usually by doing more typically,it's typically by doing less and
then maybe doing something differently.
And that's like, you know, thesethese are like nuanced
conversations that you can't have on a podcast without
talking to somebody specificallyabout what they're going through
because everybody's going to be a little bit different.
And if you've been a clinician as long as I have, you know that
there's no cookie cutter way of,of, of doing these things.

(50:07):
There's frameworks, right? And I have a framework, but I
break that framework all the time.
And I do different things if I need to, if I think it's not
going to work, but the, the goalwith the framework that it works
more the time than it does, thenit doesn't.
And I think my frameworks do that.
But again, everybody, everybody's going to be a
different place. And and I don't nobody falls
into like a very few people fallinto like on a book, a page of a

(50:28):
book with this particular presentation, you know, like,
you know, it's not, it's not, it's not real life, man.
Yeah, totally agree. I get that.
I wanted to go go into some of the products that you have
because one of them caught my eye, mainly because it seemed
like to me it had like a lot of different elements to it and the
1. And I don't want to butcher the
name here. It was blue.
Canatine. Yeah.

(50:50):
Blue canatine. OK, Yeah.
Yeah. So it's got the methylene blue
in it. It's got nicotine, looks like
it's got CBD and caffeine. So if I were to pop that, how
would I expect to feel? Like you want a prescription
stimulant, but better because itdoesn't give you the
jitteriness, the come down, the crash, the anorexia after you
finish, it doesn't doesn't mess up your sleep.
It only lasts about three to five hours.

(51:11):
It developed with very low dosesof methylene blue, nicotine,
caffeine and CBD. So it's all low dose and
synergistic. So it's not like one of them's
overpowering you compared to theothers.
It's all working at lower doses and nothing's addicting in
there. The nicotine dose is super low.
It's just a milligram in each troche and then the average dose
of each of actually most of our Turkey's, but glucanatine as

(51:32):
well is 1/2 of a Turkey. So you take a half of that and
then that, that one's better to dissolve in the mouth if you
can. And the, the upper teek and gum
has a buccal Turkey because it'sgoing to work fast.
Nicotine's very fast acting within about 5 to 10 minutes, 15
minutes for most people. Your brain's going to turn back
on. Like you're going to have better
memory, better focus, better verbal fluidity, better recall.

(51:55):
All the things that I should have done before this podcast,
but I didn't. But you know, in general, I'm
think I'm doing OK, but I shouldhave.
I typically do. I like to have some sort of
combination like that. Do you?
Yeah. What do you typically tape
before a podcast? I mean, when I first started
doing a lot of podcasts, like I did more stimulants, but I felt
over, I actually feel over the years that my brain's already
working at about 1000 miles an hour at baseline, as you

(52:17):
probably can tell. And so like for me, it's
actually actually calming down the nervous system that actually
helps me perform better. And so everybody kind of has
this experience where they are about to give a speech or
they're getting really nervous or something.
They forget all their lines, they forget what they were going
to say, etcetera, etcetera. This is because the frontal part
of your brain actually gets lessblood flow.
If you're stressed, your fight or flight nervous system, your

(52:39):
sympathetic nervous system, your, that's the one that that
kind of builds your blood flow into your limbic system.
So you're like the back of your brain.
So like your fear centers, your coordination centers.
So you can run, get the hell outof the way from a lion or you
can move out of the way from a, a raging river or whatever it
might be like that part of the brain's on, but your front of
your brain's not on. That's why like, if this has
happened to me, I remember like recently, a couple years ago

(53:01):
now, like my son was playing like at a park and he hit his
head and like, and I like, I ranover to him.
I checked him out, did all this thing like, and then like 5
minutes later, I kind of like woke up in quotes, right?
Because I had like, it was all done like just complete muscle
memory, like there was no sort of thinking involved, right?
Because it was like I was scaredfor him, right.
And so that's the kind of idea where you're, you're sort of

(53:22):
your front of your brain kind ofshuts off.
And so the nice thing about something like Tricom that we
have at our at transcriptions a little bit different has CBD and
CBG, which is another non psychoactive cannabinoid and
Cava and something called B3 GABA.
It's a nice kind of GABA that gets into the brain.
GABA itself as a supplement's too big to get across.
If you take GABA and it works for you, it's probably a bad
thing. It probably means that you're

(53:42):
leaky leaking things into the brain that shouldn't get in
there. You know which which is called
like a leaky brain barrier. But the, the Tricom's great
because it down regulates the nervous system just a little bit
or a lot if you need it, depending on the dose.
And then you can feel your brainkind of coming back online.
So a nice combination actually is the blue canitine and the
tricom together, because the blue canitine gives you that

(54:03):
focus, that productivity and then the, the sympathetic and
the sympathetic activation. But then you also have the, the
tricom, which gives you like a little bit of that calm focus at
the same time. And so it's, it's a nice
combination if you can get the dosing right.
For me, I typically am more on the like the calm side or I, I
will take like our just blue, which is our pure methylene blue
trochi and that's the 16 milligrams of methylene blue.

(54:24):
It's great for everything we've been describing here.
We have a higher dose one for practitioners at 50 milligrams,
which is more for infection, more for acute trauma, acute
inflammation. But for day-to-day operations,
mitochondrial support the, the methylene, the just blue dosing
is great. I have a good story about that.
I have a, but there's kind of like a like in between story

(54:45):
from a dosing perspective. I work with a guy that did the
Leadville race here in Colorado,which is a ultra mild ultra
marathon here in, in Colorado. It's the highest in the world.
I think it's like 12 and 13,000 foot peaks.
And so he wanted to get, and most people are that are in the
in the performance space and he wanted to cut some time off from
the previous year. He had done whatever time he had

(55:07):
done. And then we talked and we ended
up working with him and doing 32milligrams of methylene blue
every four hours. And we did the blue canitine
every 4 hours, a full troche. And so that's, that was a full
dose of everything and of all the ingredients in the in the
blue canitine. And he cut off 3 hours from his
time from the year before. So 3 hours is not small.

(55:28):
And so the reason for this is that again, we were talking
about endurance earlier. Methyl blue is going to give you
an endurance boost. It's going to give you that
endurance boost because it doesn't, because it can act just
like oxygen your cells and help you contain to continue to make
energy more effectively for longer without having to slow
down. So that's kind of like an in
between dose for somebody that'smore on the high performance

(55:48):
side of things. And so I often have people dose
and redose methylene blue every four to six hours for longer
competitions because it that's the half life, that's how long
it's going to last and it's kindof High Peak concentration.
So yeah. Very cool that.
Well, that's good to know. And I know we're coming up.
We're coming up here on time, Doctor Scott and I want to be

(56:10):
mindful of what you got going onfor the rest of your day.
I had some some rapid fire questions.
I don't necessarily need rapid fire answers.
I just like to do these sometimes with guests.
But yeah, so yeah, and, and going back, because I know we
were talking about hyper hyperbaric oxygen therapy at the
very, very beginning, I feel like in regards to that

(56:33):
protocol, like what's the most surprising effect that someone
would feel like right away just after implementing that?
Well, the thing about hyperbarictherapy is that it's not usually
a like immediate reward kind of technology.
It's going to be something that.Builds up over time, Yeah.
I mean, if it's more of an acuteissue, you might see a dramatic
change almost automatically or immediately, like you might see

(56:54):
swelling or or bruising go down very quickly.
If you have an acute injury, youalso can see, yeah, sort of more
of the acute pathology get better faster.
So if somebody has an acute injury to their knee, you're
going to see their swelling get better, you're going to see
their bruising get better, you're going to see the range of
motion get better. All these things can happen
within a couple sessions and even from a recovery

(57:15):
perspective, you can use it likeafter a big day of a workout,
you may not feel a whole lot different in the chamber.
But I promise you, if you, if you check things like you know,
you have an or ring or you have a whoop or something like that,
your recovery score is going to be much better than you
anticipated. As long as you don't go to like
a too deep of a pressure in the chamber after you do like a long
workout, heavy workout. So there's nuances with that,
like as far as which pressure isbest for what on their soft

(57:36):
chambers that go to milder pressures, harder chambers that
go to deeper pressures. But in essence, you have to be
mindful the kinds of pressure you're using to make sure you're
going to get benefit from a recovery perspective rather than
causing more stress in the system.
Makes sense? What's the?
Biggest myth about longevity medicine you wish people would
stop believing? Well there's a Greek myth that

(57:59):
goes along something like this where if you have a genie and
you can ask for 3 wishes, the first one you ask for is eternal
life. The second one or third one,
better asking. Better be asking for eternal
youth at the same time. So you don't want to just live
longer, but you want to live healthier as well.
So, so I think that longevity isa little bit more appropriate to

(58:20):
say as health span, right, because most people want to live
a long time and then die as healthy as possible kind of
deal. And so that's kind of the, I
think the thing about longevity medicine that I like to reframe,
it's not, no, it's not about living as long as you can.
It's about living as healthy as you can for as long as you can.
And so, and most of us would youto live as healthy as we can
rather than as long as we can ifwe had to choose, right.
So living, living 20-30 years ofhaving morbidities, you know, we

(58:42):
know that, you know, women especially have significant
amounts of morbidity when it comes down to how they live
longer than men, but they have alot more years of, of chronic
issues compared to men because men don't live as long.
But so I think the biggest thingis to change the, the, the
conversation between from longevity to health span.
And that's actually what we do at health optimization medicine.
Actually, we actually change andshift the perspective from
disease to health and also shiftthe perspective from longevity

(59:04):
to health span to looking at things from optimizing levels of
vitamins, minerals, nutrients and cofactors when you were 21
to 30 years of age. That's one of the most optimized
to do all the things, be most resilient to fight, to flee, to
fornicate and everything else and get up the next day and do
it all over again without complaining, without having less
energy, because again, that's one of the most optimized.
So why shouldn't we have optimize levels of vitamins,

(59:25):
minerals, nutrients and cofactors, hormones and
neurotransmitters to when we're those of ages?
And so that's the idea with health optimization medicine.
Shift their perspective and conversation from longevity to
health spend. Well said.
Yeah and it's funny, I was just thinking but I would I rather
live to 120 and be decrepit or die at 90 with like most of my
motor skills and my ability to walk and function.

(59:47):
I'd I'd take dine at 90 all day.Most people wouldn't.
Yeah, rather than just living for another 20 or 30 years or
anything like that. OK, last question.
So I know you were talking aboutthe Leadville runner that was
supplementing with methylene blue, taking, you know, a few
hours off of his time for the previous year.
What's the most jaw-dropping transformation that you've seen

(01:00:09):
with the client? Jaw-dropping.
I mean, a couple come to mind indifferent.
I mean, I've been doing this fora long time.
And so there's like, it's hard to just pick a couple of the
ones that come to mind here. So for methylene blue, I'll give
you a couple stories. One was a lady that got some
methylene blue early on, maybe in 2020-2021.

(01:00:32):
Our just blue for her grandmother.
Her grandmother had mild cognitive impairment, lived in
the US, was from Mexico originally and gave her some
methylene blue and she started telling stories about her
childhood that nobody had ever heard of before.
The methylene blue just started just waking up her memory, her
memories just started coming outand flooding.
And so everybody started surrounding her there.
She was telling stories and she maintained taking methine boot

(01:00:54):
for a long period of time after that and the grandmother was
doing so much better and the granddaughter was very happy for
that. Another story lady that had
she's a physical therapist for many years but had long COVID.
No excuse me, physical therapistfor very many years and had mold
exposure and because mold was out of work, had the mold
remediated in her house in her body.

(01:01:15):
But she still felt terrible. This is pure mitochondrial
dysfunction. She started taking like 4 or 8
milligrams of methylene blue andwithin two weeks she was back to
work. She felt so great.
And these are really relatively early on that I remember them so
well because it was kind of shocking to me how well they
worked in some ways. I mean, of course, when you,
when you do theoretical modelingand we and we did clinical

(01:01:37):
testing with everything, we had some good benefits, people
seeing more energy, less brain fog.
I had one guy recently in the last couple months, he's like
Doctor Scott, I started taking your methane and blue.
My anxiety went away. I was like, your anxiety went
away. Really.
He's like, yeah, I had all this anxiety all my life and then I
started doing methane and blue. It was gone.
I was like, well, that's interesting, right.
So like what is, what's the sortof the reason for that?
I think there's multiple, I think there's a mitochondrial

(01:01:58):
piece to that. I think there's a
neurotransmitter piece to that. And so I've just been impressed
really with this compound over the years in that, in that
capacity. I think I've had a number of
them on the other side of thingson the Gabaergic side.
So I talked about this kind of, you know, in passing briefly
when talking about giving peoplethe experience of feeling like

(01:02:19):
their midstress is actually doneand, and they're in
parasympathetic mode and I-1 patient that this was
transformative to her to understand that she'd been in
fight or flight for years and years and didn't know it until
she felt like it was not to be in fight or flight for the first
time in many years, had this reactive anxiety.
We worked her through it and then she knew what there was and
she knew how to get back there. Well, she didn't know how to get
back there, but she knew where there, there where, well, you

(01:02:41):
know what, what there there was.You know what I mean?
Like she knew what like that feeling.
And so as a result, she, you know, we worked with her for a
long period of time and she was able to down regulate her
nervous system and can become a much, much better balance and
feel much better from a day-to-day basis.
On the hyperbaric side, I've hadtons of cases over the years,
people with, with concussions. One kid always stands out to me,

(01:03:02):
was a skier, 3 or 4 concussions,was never able to ski again, was
never told he was never going toski again.
Wasn't doing well in school, wanted to kill himself.
Got like 10 of hyperbaric, hyperbaric.
I'm thinking maybe 10 hyperbaricsessions overall initially and
he was completely better. He's like, I feel great.
Like no, no, no more mental health issues, no more
headaches, no more dizziness. He had all those symptoms too.

(01:03:24):
That's awesome. So I didn't want him going back
to skiing and I told him that, but but symptomatically he was
completely better. And so like, those are some of
the stories that stand out to me.
Very cool. Before we wrap up here, anything
new coming up for you? Anything that you're working on?
Well, just, you know, building my companies, you know, I have
the transcriptions company that we make tons of products that
are really helping people right now along that path.

(01:03:45):
You know, we have our just blue and blue canatine.
Those are the ones with methylene blue in there.
The methylene blue nicotine, caffeine and CBDS are blue
canatine. We have our GABA Urgic stuff and
really trying to get more education out on that
sympathetic spiral of doom that I mentioned a couple times,
which is sure, got to break the spiral.
If you want to feel better, if you want to heal, if you want to
recover, if you want to be performing at your best.
And if you're an endurance athlete, if you're an endurance
athlete, there's a very high likelihood that you're spending

(01:04:07):
more time and you're supposed toin fight or flight mode, you're
not getting enough recovery. It's just in general, all of us
like to work. We always like, we don't like to
rest, but resting is just important, if not more important
when it comes down to it. Also, you know, new products are
always coming out. We have things coming out for
pain, for for mood, for stress. Additionally, we have a whole
practitioner line of products aswell.

(01:04:29):
So if you're a practitioner, youcan get your own account on our
practitioner portal, sign up andget webinars, interviews,
lectures, physician guest references, those kinds of
things and discounts on productsfor your, for your offices or
for your online stores and, and things like that.
So I'm always building, always growing.
And you know, that's, that's thedeal, man.
Yeah, absolutely. I love it.

(01:04:49):
Well, this was fantastic. Where can people find you
online, get in contact with you,work with you, all that good
stuff? Yeah, So easy place to find me
every everything is sort of one place is Doctor Scott sure.com,
DRSEOTTSH, err.com. So that's where most of my stuff
is sort of how is there's my hyperbaric consulting there,

(01:05:10):
there's my health optimization medicine consulting there as
well. There's also links to my
company's transcriptions, link to my company.
I don't know if you can hear my dog.
Is that you can hear him? Yeah, it's OK.
Yeah. So links to my company's
transcriptions link to my company's health optimization
medicine practice, the nonprofitorganization also link to my my

(01:05:31):
company that's involved in the hyperbaric space called one base
Health. So you can check out all there
and then on Instagram at I'm at Doctor Scott sure, DRSCOTTSHERR
transcriptions at transcriptionshealth optimization medicine at
home hope org. I think that's it.
So yeah, if you're interested, check it out, check out
transcriptions, check out some of the work, lots of education
on our platforms. That's what I'm here to do so.

(01:05:52):
Yeah, very. And, and I very much appreciate
you taking the time. I'll put everything in the show
notes. Yeah, this was awesome.
And thank you guys so much for listening to the Low Carb
Consultant podcast. We'll catch you guys on the next
one.

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Dr. Scott Sherr | Methylene Blue & The Science Behind Health Optimization | September 12, 2025 Ep. 24

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.css-14f5ked{margin:0;word-break:break-word;display:-webkit-box;-webkit-box-orient:vertical;box-orient:vertical;-webkit-line-clamp:2;overflow:hidden;} Dr. Scott Sherr | Methylene Blue & The Science Behind Health Optimization | September 12, 2025 Ep. 24