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July 18, 2025 19 mins

In this enlightening episode of The Nightshift, Shane Hewitt welcomes Dr. Sean Wharton, a leading voice in obesity medicine and internal medicine based in Burlington, Ontario. The conversation kicks off with the groundbreaking results from a new study published in the New England Journal of Medicine, highlighting the drug CagriSema—a combination therapy showing 20–30% weight loss in people with obesity but without diabetes.

Dr. Wharton, who has been at the forefront of this research, breaks down the science in a clear, respectful, and empowering way. He explains how CagriSema builds on the success of medications like Ozempic and Mounjaro, and why this represents a paradigm shift in how we treat obesity—not as a lifestyle failure, but as a chronic, relapsing disease.

Originally aired on 2025-07-17

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