Clinician's Roundtable
Tune in to interviews with the top thought leaders in medicine exploring the clinical and professional issues that are foremost in the minds of the medical community. Join us at the Clinician's Roundtable for discussions on a vast range of topics that every medical professional should know about.
Episodes
Obesity introduces distinct changes to respiratory physiology that ripple across care settings—from subtle outpatient symptoms to complex ventilatory challenges in the ICU and heightened perioperative risks. Dr. Sujith Cherian explains real-world scenarios and physiologic insights to show how excess weight influences not just lung mechanics, but length of stay, postoperative ...
With obesity rates rising to unprecedented levels, clinicians face critical challenges in managing associated complications. Hear from Dr. Sujith Cherian as he explores obesity’s systemic impact, from cardiovascular and infectious risks to medication dosing and hospital care complexities. Dr. Cherian is an Associate Professor in the Divisions of Critical Care, Pulmonary, and ...
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing liver health concern that's closely linked to obesity and other cardiometabolic risk factors, yet it remains underrecognized in clinical practice. That's why Dr. Peter Buch joins us to discuss how emerging perspectives are changing the way we think about metabolic-related liver disease. D...
A new preclinical study investigated whether Roseburia hominis, a gut microbe often depleted in individuals with obesity, could play a direct role in regulating metabolism. Learn more as Dr. Hallie Blevins explores these findings and their potential implications for future treatment of obesity and related metabolic disorders in this AudioAbstract.
Host: Ryan Quigley
What does it really mean to humanize medicine? In this candid conversation, Ryan Quigley and Dr. Michael Greenberg explore how clinicians can revive empathy, trust, and emotional connection in patient care, from intentional language shifts to brief yet meaningful moments of authentic connection. Dr. Greenberg is a dermatologist at the Illinois Dermatology Ins...
Guest: Anna Miller, MD
Guest: Michael Weaver, MD
Timely surgical intervention is critical for reducing mortality and complications in high-risk hip fracture patients. However, anticoagulation therapy often presents barriers to prompt care, requiring careful coordination and clinical judgment. Joining Dr. Steve Jackson to discuss anticoagulant reversal strategies and mult...
Guest: Caterina Garone, MD, PhD
What if a rare, progressive neuromuscular disease like thymidine kinase 2 deficiency (TK2d) could not only be stabilized, but partially reversed? Based on findings from a pooled analysis of pediatric patients, pyrimidine nucleoside or nucleotide therapy reduced mortality risk up to 95%, with nearly 75% of patients regaining at least o...
Guest: John B. Hertig, PharmD, MS, CPPS, FASHP, FFIP
From minimizing wrong-drug and dosing errors to easing cognitive burden in the OR, ready-to-administer (RTA) medications are enhancing both safety and efficiency in anesthesiology and perioperative care. Join Dr. Charles Turck and Dr. John Hertig as they explore key medication safety challenges, compare FDA-approv...
Guest: Cristina Domínguez González, MD, PhD
How fast does thymidine kinase 2 deficiency (TK2d) progress without intervention? That’s the question explored by the largest dataset to date on untreated pediatric-onset TK2d, and the results reveal a median survival of just 2.6 years from symptom onset. Additionally, more than 80% lost at least one motor milestone, and m...
Guest: Philip Yeske, PhD
Caring for individuals with thymidine kinase 2 (TK2) deficiency can place extraordinary demands on families, yet caregiver experiences are often overlooked in clinical care. To shed light on this burden, a mixed-methods study explored the physical, emotional, and financial impacts on caregivers. Here with Dr. Charles Turck to share the findi...
Emerging research suggests that the effects of obesity extend beyond metabolism, reaching the brain in ways that may influence the development of Alzheimer’s disease. Tune in as Dr. Stephen Wong discusses how fat-derived vesicles act as molecular messengers, potentially linking systemic inflammation and lipid imbalance to neurodegenerative changes. Dr. Wong is the John S. Dunn Presidential...
A cross-sectional study in Frontiers in Endocrinology assessed the triglyceride–glucose (TyG) index as a potential screening marker for prediabetes in children and adolescents with obesity. Hear from ReachMD's Ryan Quigley as he discusses the findings from this research and explores how the TyG index could provide an accessible tool for early risk stratification.
Emerging data reveal a troubling trend: individuals with higher body mass index are significantly less likely to receive routine cancer screenings, raising urgent concerns about care equity. Join Dr. Vance Albaugh, Assistant Professor of Metabolic Surgery at Pennington Biomedical Research Center and Louisiana State University, as he dives into the findings from this analysis.
How often are ICU patients conscious during intubation despite paralysis? Hear from Dr. Yana Zemkova as she discusses new findings on the incidence of awareness with paralysis and the urgent need for improved monitoring in critical care. Dr. Zemkova is Clinical Assistant Professor of Internal Medicine specializing in Pulmonary, Critical Care and Occupational Medicine at the University of Io...
A large retrospective study across 38 endocrinology clinics in Turkey showed that liraglutide led to meaningful weight loss and metabolic improvements—even at slightly reduced doses. Hear from ReachMD's Ryan Quigley as he reviews recent real-world data on this GLP-1 receptor agonist.
Obesity impacts how the lungs function in a variety of ways, and understanding these impacts is essential for interpreting pulmonary function tests, identifying restrictive or obstructive patterns, and managing ventilation. Learn more with Dr. Sujith Cherian, who's an Associate Professor in the Divisions of Critical Care, Pulmonary, and Sleep Medicine at University of Te...
Cytology via thoracentesis remains the first-line approach for diagnosing malignant pleural effusion (MPE), yet its sensitivity is limited. leaving many patients undiagnosed or delayed in treatment. In this expert-led discussion, Dr. David Feller-Kopman explores the limitations of current diagnostic methods and the evolving role of biomarkers in enhancing both diagnostic accuracy and...
Discussing weight with pediatric patients and families is a nuanced challenge shaped by stigma, culture, and access—but it’s also a vital opportunity for early intervention. Dr. Jaime Moore shares how to build confidence, counter bias, and leverage practical tools and partnerships that support long-term, personalized care. Dr. Moore is an Assistant Professor of Pediatric Nutrition at the Uni...
Guest: Sarah Sammons, MD
About 40 percent of patients with metastatic HR+/HER2- breast cancer have an activating mutation in the PIK3CA gene,1,2 which plays a key role not only in tumor growth, but also in driving resistance to endocrine therapy.3-5 And while there are several FDA-approved PI3K pathway-targeted agents for patients with PIK3CA tumor mutations,6-8 the...
In a 2025 study investigating salivary metabolites as potential biomarkers in cystic fibrosis, researchers identified distinct metabolic patterns linked with key complications as well as correlations with lung function. In this AudioAbstract, Ryan Quigley discusses how a simple saliva sample could provide clinicians with an accessible, non-invasive tool to stratify patients, monitor therapies, a...
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