Scott Sherr: GABA: The Breakthrough Your Brain and Body Have Been Waiting For

In this episode of Accelerated Health with Sara Banta, I’m joined by Dr. Scott Sherr, a Health Optimization Medicine and Hyperbaric Oxygen Therapy Physician, to uncover the incredible role GABA plays in supporting your brain, body, and overall wellness.

We discuss how GABA impacts stress, sleep, mood, and energy, and why this powerful neurotransmitter could be the key to unlocking better mental clarity and physical performance. Dr. Sherr also shares cutting-edge insights from health optimization medicine and practical tips you can implement today.

Whether you’re struggling with sleep, stress, or low energy, this episode is packed with science-backed strategies and actionable advice to help your body and brain thrive.

🌐 Guest Website: https://drscottsherr.com/  

Supplements Featured In This Episode:
• Acceleradine® Iodine https://www.acceleratedhealthproducts.com/products/acceleradine-iodine-supplement 
• Accelerated Cogniblast® https://www.acceleratedhealthproducts.com/products/cogniblast-nootropic 
• Accelerated Colloidal Gold® https://www.acceleratedhealthproducts.com/products/accelerated-colloidal-gold 

Not sure what food to eat and avoid? This guide is for you.⬇️

📚 Accelerated Food Guide https://www.acceleratedhealthproducts.com/blogs/articles/accelerated-food-guide  

🥩 Here’s a link to the cleanest meat delivery service out there: forceofnaturemeats.pxf.io/AHP 

📖 For health articles, podcast episodes, and more visit: https://sarabantahealth.com

⚕️To our nursing audience members, our podcasts qualify for nursing CE. For more information visit http://www.rnegade.pro/ 

🛒 Get 10% off supplements at Accelerated Health Products: https://acceleratedhealthproducts.com and use code PODCAST10 

📱To access my FREE Health & Wellness Coaching Group, join Telegram and then click on: https://t.me/ACCELERATEDHEALTH 

🗓️ Enquire about your own free tailored supplement plan:https://sarabantahealth.com/health-goals-form/ 

🔔 For health updates and cutting-edge health technology subscribe to my channel: https://www.youtube.com/AcceleratedHealthSaraBanta?sub_confirmation=1 

👩‍⚕️Join My Social Community
https://www.instagram.com/acceleratedhealthproducts/        
https://www.facebook.com/acceleratedhealthproducts/  

🎙️Tune in to Accelerated Health with Sara Banta on Monday, Wednesday and Friday on Apple Podcasts, Spotify, iHeartRadio, YouTube Music, Amazon Music, Pandora, Audible, Roku, Amazon, and over 100 other podcast outlets.https://link.chtbl.com/sOiD2L1Y?utm_source=yt&utm_medium=link 

📺  You can watch the episodes on YouTube and e360tv.

Episode Transcript

Speaker 1 (00:12):
Any health related information on the following show provides general
information only. Content presented on any show by any host
or guest should not be substituted for a doctor's advice.
Always consult your physician before beginning any new diet, exercise,
or treatment program.

Speaker 2 (00:31):
Are you anxious stressed? You can't sleep and you reach
for the anti anxiety anxiety medication or the alcohol and
that only helps a little bit. But we're gonna start
talking about a little known neurotransmitter that maybe your doctor
hasn't talked to you about. Welcome to Accelerated Health of
Sarah Bianta, the podcast that gets straight to what works.

(00:54):
I'm Sarah, certified nutritionists and founder of Accelerated Health Products.
Here we cut through the noise bring you real strategies,
powerful supplements, and natural solutions that actually work to help detox,
boost your energy, and balance your body for optimal health.
So let's dive in. We have doctor Scott Sure here.

(01:15):
He's a Board certified internal medicine physician and the COO
of Troscriptions. He is certified in health optimization medicine and
specializes in hyperbaric oxygen therapy. Welcome Scott, how are you today?

Speaker 3 (01:30):
I'm good, Sarah, it's going to be here. Thanks for
having me.

Speaker 2 (01:33):
You know, dopamine serotonin, they get a lot of press
I do. Everyone always talks about that dopamine hit and
how's your serotonin levels and all of this, and there's
this one little molecule that no one talks about called GABBA.
So I'm super excited to give another tool in the

(01:54):
toolbox to people to help with the stress. We are
all chronically stress and the pandemic has physically changed our
bodies to actually make things even worse in this scenario.
So let's dive in. What is gabba?

Speaker 4 (02:14):
Well, I appreciate you having me on, sarahcause I think
this is such an important topic because as a clinician,
you know, as your clinician, I'm a clinician, Like, we
don't think about gabat efficiency as being a problem. We
think about serotonin deficiency being a cause of depression. But
guess what, that's not actually true. We now know that
people with depression people that do not have depression have

(02:37):
the same amount of serotonin. So when I was in
medical school, I was taught that people with depression have
a serotonin deficiency. That isn't the case. But interestingly, there
is actually some very compelling out of evidence that gabat
efficiency is much more associated with depression than serotonin deficiency is.
So GABA is the unsung hero. You talked about some

(02:59):
superstar neurotransmitters, neuropnefrent, dopamine, serotonin, GABBA is the one that
actually regulates them all. GABA is our primary inhibitory neurotransmitter.
It's the one that calms down the firing of the brain.
It's like the breaks of your brain. Now, interestingly, GABA
is always in balance with your actually your primary excitatory

(03:22):
neurotransmitter called glutamate. Most people haven't heard of glutamate either,
but glutamat is actually your primary excited to a neurotransmitter.
Between glutamate and GABA, that is eighty percent of your
brain's neurotransmission, and GABA itself is twenty percent of your
brain's neurotransmission. So it's a huge amount that's happening between
these two. And so glutamate is converted into GABBA in

(03:44):
the brain. It requires vitamin B six and magnesium to
do this. The challenge is that when you're stressed all
the time and your fight or flight system is not
getting out. It's always in that space. You deplete GABA
very quickly. And what happens when you deplete GABA very
quickly is you get glutamate toxicity kinds of symptoms. You

(04:07):
get anxiety, you get depression, you get insomnia, you get tremors,
you get mental health disorders. The way I like to
kind of describe this for my patients is that GABA
is like this regulator. It actually allows you to regulate
information that's coming from the rest of the world, and
it's like a gate to that information. If you are
looking around your room or wherever you are right now

(04:28):
and processing all that information, it would overwhelm you. The
color of the wall, the color of the paintings, the smell,
the sound, the light. Our body is processing this, but
we're not consciously doing it all. GABA is a gate
to all that it works. It's called an inter neuron.
It's a neuron that stays in between other neurons to
help regulate the firing and so on. Average, we have

(04:50):
about seventy thousand thoughts per day. Seventy thousand thoughts, Okay,
if your GABA system is disregulated, that can go up
to about one hundred and twenty thousand thoughts. More so,
this is what happens with anxiety. This is what happens
with depression. It's not like these are different thoughts, singular
different thoughts. Every one of those one hundred and twenty
thousand it could be the same thought over and over again.

(05:12):
And so what I always tell my patients here is
don't believe everything you think. If on average you're having
seventy thousand thoughts per day, and if you're gabat efficient,
all of a sudden you're having one hundred and twenty
thousand thoughts a day, Like that's why people feel so
jumpy and all over the place and wired but tired.
And so if you mind the GABA system by doing
it with supplementation if you need to, doing it with

(05:34):
dietary and lifestyle changes if you can, and then looking
at groundwork of your foundational biology all at the same time,
that's when you can see massive shifts in the depression
and the anxiety and the insomnia, in the tremors and
the mental health issues. Many of us think that it's
I just need more stimulation to feel better, and the
answer oftentimes is now.

Speaker 3 (05:54):
You actually need less.

Speaker 4 (05:56):
You need your GAVA system to come back line and
you're going to feel better much more sustainably over.

Speaker 3 (06:01):
The long term.

Speaker 2 (06:02):
Okay, So with antidepressants and anti anxiety anxiety medication, how
is that mechanism working on serotonin, dopamine and GABBA And
following with that, I mean, the body is such a
miracle and it's so complicated and a lot of medications,

(06:25):
and tell me if this is the case in this situation.
A lot of medications go after one thing disrupt the
natural balance of all these other things that are going
on in the body. So can you go into the
different how GABA interplays with serotonin and dopamine and then
where the medication will react or act upon those neurotransmitters.

Speaker 4 (06:49):
That's a great question, a great set of questions. I
think the first thing to mention there is that most
anti depressants have nothing to do with the GABBA system
that are prescribed. Even most people that go within anxiety
that go to their medical doctor or conventional doctor will
get an SSRI. I was in when I finished my
medical school training my residency in internal medicine. The first
year that I left training, I worked with a practitioner

(07:14):
in the city of Baltimore, and it was a working
cla area of Baltimore. Anybody that came in with a
fatigue diagnosis, with anxiety diagnosis and depression diagnosis.

Speaker 3 (07:24):
They all got SSRIs.

Speaker 4 (07:25):
Okay, these drugs work on serotonin receptors. They increase serotonin.
Some of them also increase norpinephrin. Some of them also
increase other neurotransmitters as well, but not the GAVA system.
In fact, it wasn't until recently that the first antidepressant
for postpartum depression came out about a year or two ago.

(07:47):
Now that is working on the GAVA system. What's interesting
about that, Sarah, is that it works immediately. That's why
it's being used in postpartum depression. Most drugs like the
SSRIs and antidepressants of the world take or six weeks
or longer to potentially work, and they also have a
black box warning on them that may increase your suicidality
when you first start taking these drugs too. I actually

(08:09):
know the person who got that black box warning on
the SSRI medications because her sister killed herself after being
on them for two weeks back in the nineteen nineties.
So these drugs are up to nine, and we now
know that depression is not necessariotone deficiency, and so you kind
of dovetail this to the only drug right now that
works immediately in depression for postparder depression is a GAB

(08:31):
a agonist that works on the GABBA receptor and on
the anxiety side of things, if you have anxiety and
you go to your primary care doctor or a conventional doc,
they will often prescribe you benzodiazepines. These are a class
of drugs that work on the GABBA receptor. Actually, but
what's the problem here, and this is what you're kind
of alluding to with kind of these singular drugs or
what they could potentially d do to the other receptors,

(08:51):
is that benzo's like adavan, valume xanax and things like that,
and alcohol too, by the way, does the same thing
bind very very tightly to that GABA receptor on a
separate site to where GABA would bind. They're called positive
allosteric modulators of the GABA receptor. That's a long phrase
just to say that when they bind, they bind very tightly,

(09:12):
and they deplete GABBA very very fast when they do that,
So you're depleting GABA very very quickly, and then the
receptor is through this feedback mechanism and go, oh wait,
we need to have less of these receptors. And so
over time you get tolerance, you get withdrawal, you get dependence,
and this is what you can die if you're taking
benzos for a period of time and you stop them immediately,

(09:33):
you can stop. You can actually die if you stop
drinking the alcohol immediately, if you've been drinking a lot
of alcohol for a long period of time. This is
because that GABA receptor is so insensitive to gabba is
because of having so much GABA forced into it for
such a long period of time. You get these glutamated
toxicity symptoms, you can get seizureies, you can die if
you're not careful. And so the problem there is that

(09:54):
you're giving something that's enhancing the gava system by making
GABA to bind very very tight to it and causing tolerance, withdrawal, independence,
And so the benzos of the world do this. Sleep
drugs do this, like your Lunesta, your ambiens, They also
bind very tightly to the GABBA receptor. Alcohol I mentioned
is very very similar to this as well. There's other

(10:14):
drugs that do it. The key really when you're thinking
about optimizing the GABBA receptor is to understand a couple
of things. The first is that there's a place where
gaba bind is to the receptor as I was mentioning,
and as a place where other things can bind that
enhance or decrease the amount for gaba to buying to
its receptor where it would bind those positive alistaic modulators,

(10:36):
the ones like benzos, alcohol and in the sleep drugs.
There are others out there too that can do this
that are from plants that are natural and that they
don't have as much potential side effects, but potentially could
cause an issue over time because they're just binding to
these separate sites in the receptor without giving a source
of GABA in it. And the most common example of

(10:56):
this is actually cava. Kava is well known. You can
get to a kava bard now it makes you feel
like you're drunk if you take it, because it's binding
like alcohol would bind to a separate site. Now, kava
is not as dangerous business in bind as tightly, doesn't
deplete gabba as much, but it can do this over time.
And the other corollary to this that's very important is

(11:16):
that GABA itself is too big of a molecule to
get across into the brain, across the blood brain barrier.
So if you take a GABA supplement and it works
for you, it's because your blood brain barrier is leaking
things in there that.

Speaker 3 (11:31):
It shouldn't wow, and this.

Speaker 4 (11:34):
Often correlates to having a leaky gut as well. So
if you have a leaky gut, you have a leaky
barrier there, you're offering an have a leaky barrier.

Speaker 3 (11:41):
In the brain.

Speaker 4 (11:42):
And then this is so common in people that have
chronic brain fog, chronic fatigue, long symptoms of viral infections
because of that sort of massive inflammation that the body
is under. It causes inflammation in the gut and it
causes inflammation in the blood brain barrier. It's always kind
of a chicken before the egg here a little bit
to what started the whole process. So if you take
GABA by itself as a supplement and it works for you,

(12:06):
this often means that you have a leaky brain. Now
you can do something about this. It's something you can
optimize with a practitioner. But what we do, what I
think about doing in my clinical practice and how I
formulate things with our companies is that we think about
how we can optim optimize the Gaba receptor without giving
gaba itself. The things that can modulate the GABBA receptor
by combining something that works allosterically that binds on a

(12:29):
separate site to where Gaba would bind, along with giving
a supply of Gaba to the narrow transmitter system so
you don't deplete it at the same time. And that's
what we call an obligate pair. So I know that's
a little bit complicated, but in essence, what we're trying
to do is support the GABA receptor immediately by supplementing
it in a way that doesn't deplete gabba. And then
if you don't deplete kaba, then you're not going to

(12:49):
cause tolerance withdrawal independence. And of course in other ways
to do this other than supplementation, but the fastest way
to downregulate the nervous system and get at a sympathetic
overage is to enhance the gava system full stop.

Speaker 2 (13:03):
Amazing. Okay, So I didn't know that gabba supplementation didn't
cross the blood brain barrier. So even if it's not
getting to my brain, is it is there any benefit
to the rest of my body taking a gavas supplement, So.

Speaker 4 (13:19):
Unfortunately the answer is no. However, I would say that
there are things that you can take that can modulate
the GAVA system by actually that don't need to get
through the blood brain barrier to do it. One of
them would be taking a probiotic actually Biffitobacterium and Lactobacillus.
These are types of bacteria that modulate the GAVA system
via the vegus nerve that goes from the brain or

(13:41):
comes from the brain, or goes up to the brain
through Basically it goes travels the nerve is from the
brain into the rest of the body, but it goes
in both directions is what it comes down to. And
so the vegas nerve takes the signal from the gut
and this bacteria to help calm down the firing of
the brain. You can also take other supplements it can
get across into the brain that are not GABA itself
that can modulate it, things like cava I mentioned already,

(14:04):
Hano kyo or honocchio, if aunt, magnolia, bark, CBD, CBG,
and CBN. All the non psychoactive cannabinoids they actually modulate
the GABBA receptor in a positive weight, except for THG,
which actually does the opposite. It blocks the GABA receptor.
That's why I can cause anxiety in a lot of people.
And so there's lots of other ways you can modulate
the GABA receptor, but the only possibility of getting GABA

(14:24):
through is taking a huge amount of it, over two
or three grams of it, or if you're taking like
a nano lyposomal version, that will potentially also get through
the blood been barrier with it also being intact. But
in general, what I do in clinical practice is I
work on it using other compounds that I'll bind to
the receptor enhancing GABAA bind and that'll also use other

(14:44):
compounds that will bind to where GABBA will bind directly,
so you don't deplete it in the process. My favorite
one that binds to where GABA binds. It's actually one
called agarin. It's a long acting molecule that comes from
the fly garrick mushroom. It is an Amanita muscaria mushroom
is the other name for it. It's a psychedelic mushroom

(15:05):
a high doses. It's also neurotoxic at high doses. But
this particular compound is not neurotoxic. It's very supportive and
it stays on the receptor for about six and a
half seven.

Speaker 3 (15:13):
Hours worth a half life of about that.

Speaker 4 (15:15):
And so you get this long acting which is great
for sleep or great for as a low dose, great
for anxiety dress relief as well. And so the key
I think for those that are listening is that supplementation
can go a long way to help support that GABA
receptor right now, so you can feel like what it
felt like to have good parasympathetic tone, rest, digest, getting

(15:37):
out of that sympathetic fight or flight, and then you
can go, Okay, how do I get here without the
supplementation all the time? Well, you can get out of
a toxic relationship. You can address the trauma that you've
had as a child that makes you not feel safe
all the time. You can stop sleeping against or with
somebody that has that's snoring all the time, for example.
You can work on your diet, you can work on

(15:58):
your lifestyle, can our meditation practice, you can start a
breathwork practice. This is what I do with my patients
all the time. But you have to know where there
is to know how to give back there, and that's
what supplementation can be very helpful for. Then it's great
in a pinch when you need to calm down the
nervous system so you can perform better. Because most of us,
I think, know this, but like most people, forget that.

(16:19):
If you're too stressed, you don't enough blood flow at
the front of your brain, you can't think that well.
This is that classic nightmare people have that they get
up in front of a room and forget what they're
going to say all they go blank. It's because they're
not getting a blood flow to the front of their brain.
And calming down the nervous system just a little bit
gets you back into that capacity to think more optimally

(16:41):
and to be able to flow back into that area
of productivity and focus.

Speaker 2 (16:45):
You're speaking my language because I always love to use
the supplements to give the person the feeling of Okay,
now I can do this, whether it's the weight loss,
or the exercise routine, or the workload or just handling life.
But if you're on your back and you're completely chronically stressed,

(17:07):
adrenal adrenals are could put and you have no juice,
you're not going to be able to do all the
things that you want to do, and that's going to
only cause more stress because you're failing at what you're
wanting to do. So I love this because when you're
in a good state of mind, then you can tackle life.

(17:28):
I really want to hit home on alcohol and the
benzos and the side effects. So here I am I start.
I'm having my glass of wine every night, then I'm
needing two, and then I'm needing three. Why do I
feel like crap in the morning? And then why am
I needing that alcohol just to get back to my baseline?

(17:50):
And same with the benzos and the medication.

Speaker 4 (17:54):
What happens over time is that you as you're drinking alcohol,
as you're taking benzodiazepines, you're changing because of feedback loops
in your brain, your brain's receptors for GABA, And as
a result of that, you're going to need more of
the same compound over time and get the same effect.
And this is the problem. Not only is it doing that,
alcohol is trashing your sleep and benzos are not giving

(18:15):
you good RESTful sleep either. Because what happens here with alcohol,
for example, so I always give me as the perfect
terrible example of somebody drinking alcohol. Alcohol trashes your sleep.
Even if you don't think it trash is your sleep,
it very likely does.

Speaker 3 (18:30):
And I promise if you.

Speaker 4 (18:31):
Get some sort of tracker and you start checking your sleep.
I have my horo same color there on mine. I
haven't had any alcohol in a long time at this point,
because I knew inherently that I slept terribly with alcohol,
because what happens with me is that I would drink
alcohol and then I would go to bed. It's easy
to go to bed with alcohol, but I would wake
up two or three hours later with a massive headache.

(18:52):
And so two things were happening here. One is that
alcohol does produce aldehydes, which can be toxic to your
liver and cause detoxification actions. But the other big thing
is that when you bind all that out, all that
GABA receptor and you de sleep GABA very quickly with
the alcohol with the benzos, what happens is once that

(19:12):
comes off the receptor, the alcohol in this case for
the benzos, you're depleted in GABA and your glutamate levels
are higher compared to your GABA levels, so you're basically
acutely glutibate toxic. Toxicity or toxic. The best other example
I can give you for this is that you've just
gone to a Chinese restaurant and you've had a bunch
of food with monestonium glutimate MSG, which is a huge bullets,

(19:34):
a huge amount of glutamate you've just gotten immediately, and
what happens. You get headaches, you get irritability, you get
you get what saying it seems like alcohol with you know,
alcohol symptoms of being hungover. That's because that's a big
part of the alcohol hangover is that glutinate toxicity. So
this is what's happening. This is why you don't want
to use alcohol as your way to wind down at

(19:56):
the end of the day, because it's going to trash
or sleep later. I mean, it's also a di irretic
that's gonna make it pem more all the other kinds
of things, right and so, but inherently, what I care
about the most is that gab of depletion that's happening
with that alcohol and the benzos, and that you feel
like you're getting to sleep better, but you're not getting
good rest. I promise you, and we know from you

(20:17):
know many different studies that if you even if you're
any benzodazepine that you take, your risk of dying from
anything goes up. Anything, whether it's getting hit by a
car or it's you know, getting you know, an accent
of any other sort, or of a heart attack. If
you've been on benzos or ambient for example, your risk
of dying is higher. It's called all cars, excuse me,

(20:39):
all cause mortality. That's because your your capacity to regulate
your breaks.

Speaker 3 (20:45):
Of your brain is not that good anymore. And so
you get acute stress.

Speaker 4 (20:50):
Your brain is going to be much acutely stressed more
compared to somebody else that has a work.

Speaker 3 (20:54):
In gabas system.

Speaker 4 (20:55):
So think about this is like you you're taking those drugs,
you are putting yourself at risk of dying from anything
more compared to not taking them. Okay, And so alcohol
really does not necessarily like I know that like in
places around the world, alcohol like for example, in Sardinia
and like these blue zone kinds of places, like alcohol

(21:16):
is much more heavily consumed, but it's also being consumed
in a social setting, in community where there's a lot
of love and peace and understanding and the stress levels
like zero. It's not like you're taking your alcohol after
your kids go to bed and you're been stressed all
day at work and finally like, okay, now I can relax. Like,
that's not what they use it for in Sardinia, man,

(21:36):
that's not how it works, Okay.

Speaker 3 (21:38):
So, like, if you're going to use alcohol like a.

Speaker 4 (21:39):
Social setting, great, do it, fine, perfect, that's great, But
just know that if you have it too close to bed,
it's probably going to screw up your sleep, Okay. And
so I'm not like a zero sum person with it.
If you're going to use in it more of like
that traditional setting. But alcohol, benzos, sleep drugs, these need
to be avoided almost at all costs unless there's a
very special circumstances where they can be helpful.

Speaker 2 (22:00):
Amazing, and just real quick to clarify the for the listeners.
What are some of the trade names the names of
the benzos, because people might not even know they're taking one.

Speaker 4 (22:10):
Yeah, so valium, xen x auta, van restoral, what else
is there? There are so many? Those are the ones
that I remember at the top of my head. But
anything with a like it's usually like benzodiazepine is the
big NUM or it's like alpaslam or it's or it's
or what I've turned to l a M at the

(22:31):
end of the of the of the word is typically
what you're going to see there. So but and then
your sleep drugs like lunesta ambient as opad M is
the other name for it as well.

Speaker 2 (22:43):
Gotcha, Okay, So the gut brain access you mentioned leaky gut,
leaky brain, and we all know that the brain is
very very directly correlated with the health of the gut.
How does this affect gabba?

Speaker 4 (22:59):
So, so, as I was mentioning earlier, there's lots of
indirect regulation of the GAVA system through the gut, especially
through microbiota that produce GABA like compounds that affect the
vagus nerve. So lack of basol some different bacterium are
the two most important ones for people to know. Acromancia
as well also has some gabba or lining. So you

(23:22):
have to remember it's a tripartheide access, which means that
it's it's the gut lining, it's the bacteria, and it's
the brain. So it's all they're all communicating together. This
is why you can hear stories of people optimizing their
gut the depression goes away.

Speaker 3 (23:36):
Well, why is that?

Speaker 4 (23:37):
Oftentimes it's because they've sealed up their gut decrease in inflammation.
You often remember that eighty percent of your immune system
is actually in your gut, and so if your gut
is leaking, your immune system is overactive. Everything else is
going to have collateral potential of having dysregulation as well.
And the brain is probably your most most common and

(23:59):
most important and piece of that, and so optimizing gut
function is going to optimize brain function. And it's difficult
to optimize brain function if the gut's not optimized. And
so I actually have a couple of patients of mind
over the years they came to me taking GABA supplements
that were working for them. We optimized their gut, we
sealed it up. The GABA supplements stopped working, not surprising

(24:20):
it anymore, right, You also want to think about this
when it comes to the precursors that are responsible for
making glutamate and then subsequently GABA and the brain. The
one that I'm talking about here that's the most important
is an amino acid called glutamine. Glutamine is your primary fuel.
This amino acid is your primary fuel of your small intestine.
So if you have a leaky gut, you need more
glutamine to heal it. And so if you're not getting

(24:42):
enough glutamine that's getting into the rest of the body
because it's too busy trying to heal up the gut,
you're not going to get enough glutamate. You're not gonna
get enough gabba as well. So I've had people that
I just started putting them on some glutamine and their
depression goes away. I've had just on their glutamine and
their anxiety goes away. But you have to be careful
here because what can happen is if you overshee, then
you're going to get the Actually those symptoms are going

(25:02):
to come back. And I have a patient of mine
now massively leaky. Got got him on some glutamine, did great.
He works out a lot, and so if you work
out a lot, you need more glutamine for your muscle.
And so we have a sweet spot for him where
he knows if he takes some glutamine it's helpful, but
if he takes too much, then he also gets glutamine
and then glutamate related symptoms of overactivation. So it's a

(25:27):
very interesting play there, and then you have to also
make sure that your patients are in my clinic, in
my practice, that there are B six and magnesium sufficient
as well as well, because we know that most people
are magnesium deficient, and then if you're magnesium defficient, you
can't convert glutamate to GABA, and if you're B six
deficient you can't do it either. I'm amongst the thousands
of other things that these two particular micronutrients are mineral

(25:49):
and micronutrient magnesium and B six, respectively, do in the body.

Speaker 2 (25:54):
You know what this is. I feel like you're talking
to me because I'm the type of person a little
good more is better, and I have a glutamine supplement
in the past for my gut, and so this is
really interesting because I never thought there would be a
downside to taking too much, not that I ever overdosed
on it, but that is really good to keep in mind.

(26:16):
I've noticed over the last five years since the pandemic.
I know we have to be careful with how we
speak about all of that.

Speaker 3 (26:25):
Still, I don't know, I don't know. I guess we
have to.

Speaker 2 (26:31):
You know, obviously stresses up, so that would hurt gabba.
I'm sure more people are on medications that would hurt gabba.
Processed foods I'm sure doesn't help with the gabba. But
is there something else going on where more and more
people are depleted in Gabba than ever before.

Speaker 4 (26:53):
I think you're on the right track here, Sarah, which
is that never before in history have so many people
bid in fight or flight so much of the time.
And I think that even back when we lived on farms,
or even before that, when we're getting chased by lions,
we were staying in parasympathetic mode most of the time.

(27:15):
That is our default state, ladies and gentlemen. Our default
state is not surveillance and hypervigilance. Our default state is
supposed to be parasympathetic activation. Okay, rest, digest, detox and
then when we need to stimulate ourselves to run away
from the lion or get out there and mow wheat
in the field with our oxen or whatever interesting image

(27:36):
that came into my brain right there, that's when we're
supposed to be getting up, getting moving and so that
we get what we need to get done. The best
example of this is if you ever watch National Geographic
and you watch some sort of prey animal get preyed
upon by a predator and they get away. Okay, so

(27:57):
they're they're they're fighting, they're fighting, they're fighting, they get away,
and then all sudden, what happens to the preyed upon
animal is they go through this like massive shaking, like
dump of sympathetic tone, and then five minutes later it's
like nothing happened. Right, And so that's what we're supposed
to do. But we have all this chronic stress that's
happening in our life at all times, and most of

(28:18):
this is self created, but most of it also is
culturally shined upon as a good thing, like self self sabotaging. Right,
Like for me in medical school, my friends and I
had shirts that were made that said sleep is for quitters.
You know, sleep is for quitters. You don't need to
do that sleep when you're dead. Or I grew up

(28:39):
about an hour and a half east of New York City,
but the hustle culture like the city that never sleeps.
And so we need to deprogram all of that because
what I found over the years, and again I need
to take my own medicine off in times too, because
my default is to go go work, but we have
to remember, and I have to remind myself this on

(28:59):
a regular basis, that doing less will actually allow you
to do more than just shoving more work in front
of your face. And this is something that I have
a very difficult time with I will play personally. So
I'm like, I just need to keep going right, But
I'm like, no, take a break, take a break, you know,
and then reset yourself and then you're going to do
what you're going to do better, work right, And that

(29:21):
just how it goes. So I think the answer to
your question is that we're more gavit efficient than ever
and we're more dysfunctional from a regulatory from a nervous
system because of this as well. But there's there is
a light at the tunnel on at the end of
the tunnel. We can work on this and we can
see massive benefits, which is a few things both die

(29:41):
lifestyle and then supplementation can be really helpful here too, obviously.

Speaker 2 (29:45):
Yeah, you know, I was talking to my daughter yesterday
actually because she's very much like me type a personality,
and she's like, I don't know what to do with
myself when I'm board, and I feel like, you need
to keep doing things, And I said, you need to
put on your calendar self care, like an hour of
self care or or just an hour of break and
so then you feel like you're accomplishing something by checking

(30:08):
it off the box that you're resting or doing that
self care. Okay, so I want to talk about your
GAVA supplement and how it works. So it's not going
to deplete us, it's not going to take us up
and down like alcohol and all of the other things
we talked about, and then how to support that Once
we get that feeling back, then what do we do

(30:30):
with diet and lifestyle to support it.

Speaker 4 (30:33):
We created something called an Obligate pair strategy at Prescriptions,
which is the name of my company. And the cool
thing about this is that you can enhance the GAVA
system immediately without potentially depleting GABA in the process. And
we do that combined combining what we call alistairic modulators
that bind too separate sites on the GABBA receptor that

(30:53):
increase the amount of gaba to buy and increase the
affinity for gaba to bind, and also give something that
works just like gasa or is gaba itself through a
circuritius route which I'll demonstrate. So we have something called
tro Comm. Trocom has a compound in it called B
three GABBA or nicotineal gaba, So it's vitamin B three
attached to a GABA molecule. B three has a transporter

(31:15):
that gets across into the brain. Even if you have
an intact a brain barrier. In the brain, it hydrolyzes
or breaks up into B three and GABA, so it's
giving you a direct supply of GABA, and it's also
giving you some B three, which is actually interesting because
B three what turns into nysin and nad, so it's
mildly activating. So you can take the trocom and you
can feel more relaxed, but you don't feel tired at

(31:36):
the same time, so it gives you the anxalytic effect,
the anxiety reduction without sedation. And then in addition to
the B three GABBA, it haskva, cbd and CBG, So
cbd and CBG are non psychoactive cannabinoids that bind to
the GABA receptor that increase GABA to bid that those
allosteric sites, and then cava does it as well. Cava
binds to a separate site that aloseric site on the

(31:58):
GABA receptor that increases the affinity for GABA to bind.
But surprise, you actually have gaba that's being given to
you at the same time, so you don't deplete gabba
at the same time. Now, those non psychoapticts, those nine
excuse me, those non psychoactive cannabinoids also work on different
sites in the brain, the endocannabinoid system, the serotonin system
a little bit, but mostly they work on the endocannabinoid

(32:20):
system and the gabba system. So you have this beautiful
combination where you're increasing amount of gaba urgic tones, you're
down regulating the nervous system, and you're getting more gaba,
getting those breaks to go on, but you're doing without
really sedation, which is really really nice. And then we
have another combination that we use in a product called
Trozy that combines onokiol, which is from Magnolia bark, which

(32:42):
is working as a allosteric modulator of that GABA receptor
soubinding to a separate site in the gabba receptor, increasing
the amount of gaba to bine. Combining with it this
from the agarin excuse me, from the psychedelic mushroom, the
flaggerriic mushroom, the Amanita mushroom. It's called agron and Agron
is a long acting on that GABA receptor I mentioned

(33:04):
it earlier, and that one binds to where GABA would
bind on the receptor, so that combination is very very
supportive to the GAVA system and.

Speaker 3 (33:14):
Does not deplete GABA in the process.

Speaker 4 (33:15):
And then in our Troezy which is our sleep formula,
we're also working on four other neurotransmitter systems at the
same time. All that work on sleep. Your serotonin system
by giving five htp, your melatonin system by giving melatonin
which helps with circadian rhythms to help with sleep maintenance.
We're also working on the a dentosine system. A denosine
is a neurotransmitter that helps with sleep pressure. We use

(33:38):
something called cortis spin for that and cord as sepans
from the cordyceps mushroom, the most active component of the mushroom,
very good for deep sleep, also increases meine system function.
It's an antiviral, it's an antibacterial. It's also increasing deep sleep.
As I mentioned, we also have another product called Trimmune
that has just cortycepin in it. And then we have
a dentosine in there, which also obviously works on the
adenosine system, and we have CBD and cpen in trozy

(34:01):
that are working on the endocannabinoid system but also working
on the GABA system as well.

Speaker 3 (34:06):
So it's a very.

Speaker 4 (34:06):
Supportive, very comprehensive sleep formula that helps you fall asleep
and stay asleep, and if you do end up waking up,
you can typically go back to bed. But the key
is that if you can regulate the GAVA system, you're
going to feel better. Even if you think more stimulation
is the answer, I promise you it's probably not. If
you can think about just down regulating your nervous system

(34:28):
a little bit, getting into that parasynthetic mode. You may
feel a little bit tired initially, but that's okay. Your
body's going to compensate and come back to a different
set point if you can get.

Speaker 3 (34:39):
It there more often.

Speaker 4 (34:40):
And it's important because some people when they first start
down regulating their nervous system, they can actually get a
reactive anxiety to that. They can actually react go, oh crap,
what am I supposed to do? I don't feel good,
And that's when the body is actually coming out of
fight or flight, and so it could be very disconcerting
in some people. But just know that once you get
down there, it's going to feel better, especially as your

(35:01):
body starts resets.

Speaker 3 (35:02):
It's kind of set point, you know.

Speaker 2 (35:04):
I always say, if you're not sleeping, all this other
stuff means.

Speaker 3 (35:10):
Nothing, true.

Speaker 2 (35:11):
And I you know, I went out to a football
game the other night. I got home. I usually go
to bed by eight eight thirty, and I was in
bed at ten thirty, so it wasn't even that late.
Didn't drink a sip of alcohol the next morning. I
felt like I was plastered the night before. Because your
sleep is everything and everyone knows it. However, it's easier

(35:33):
said than done. People can't sleep and then they get
in bed and they have anxiety about Okay, I didn't sleep.
I haven't sleeped it in months. So here I go again.
I'm not going to be able to sleep. So to
be able to sleep gives you that foundation of Okay,
now let's take on the diet and the exercise and
all the other things and get that reset. So I mean,

(35:53):
if if you can give a person routine sleep. And
I was talking to my mother in law about this yesterday.
I said, Okay, let's just take one thing that you're
going to try to do this week. Just go to
bed at the same time every night to get that
circadian rhythm in the right place, and then let's see

(36:14):
where we can go from there. Because it is everything,
and so I am super excited. I love all the
ingredients that you just touched on. I mean, I drink
Kravit tea all the time, and we used to have
a CBD supplement at one point and I'm a fan
of that and that helps a lot of people all

(36:34):
and the courtyceps and everything. So I love it. We're
out of time, doctor, Sure, I could go on and
on with you. I love the work that you do
and the way you explain things is so understandable for
all of us, even though you're brilliant and so thank you.
Where can people find you and the supplements that you're.

Speaker 4 (36:56):
Talking about, Well, thank you for having me, Sarah. One
thing I would just say on sleep briefly that might
help some of your listeners is that doctor Ched who
I work with. He's actually the founding pioneer of Transcriptions
and our nonprofit. He likes to say that your day
doesn't start when you wake up. It should start when
you go to bed. So if you start using it
as the first thing you check off on your list
rather than the last, it becomes more important. And believe me,

(37:18):
I've been guilty of this for a long time and
I'm continuing to work on But if you can do that,
start as your day starts when you go to bed
and not when you wake up, it's a huge shift.

Speaker 3 (37:27):
So give that a.

Speaker 4 (37:27):
Try when you're If you really interested in learning more
about me, you can check it out. My personal website
is doctor Scott Sure dot com. Just my name Dr
s c O T T S h E r R
dot com. You can find my consulting there. You can
find a little bit about me and some of the
other things that I do. And then if you're in
the company, it's Trusscriptions. It's the word trophy in the
word prescription mashed up to troscriptions. We use a dissoluble

(37:50):
lozenge called a trophy, which is something goes between your
upper cheek and gum. It takes about fifteen to thirty minutes.
It's faster acting, they're more bioavailable, and they can be
ty traded very easily. Leader products we talked about trocom
and trosy here specifically, which are the ones that are
regulate the Gabert jeginary transmitter system. Talk a little bit
a little bit about trommune which is high strength coard
to seven which is great for deep sleep as well.

(38:12):
So you can check it out at truscriptions dot com.
You can find us on the socials at proscriptions at
doctor Scott sure if a YouTube channel where we have
stuff that comes out every week as well on educational topics.

Speaker 3 (38:23):
So I think those are the name and mad places.

Speaker 2 (38:25):
Thank you, Sarah, amazing, well, thank you for joining us today.
A wealth of knowledge and it's definitely a neurotransmitter that
I'm going to be more focused on and I think
more people are learning about it because of you. So
thank you, Doctor.

Speaker 3 (38:39):
Shir My Pleasure. Thank you.

Speaker 2 (38:42):
Wow. Doctor sure is sure a wealth of knowledge and
who is not suffering from anxiety and stress? Right? And
the supplements sound amazing. And I just wanted to mention
a couple other ones that compliment what he's been talking about,
and the first one is iodine and accelerating iodine because

(39:03):
ninety six percent of you are deficient and idine just
like your deficient and magnesium and a lot of the
other nutrients he was talking about, but iodine deficiency is
the number one cause of depression. It supports the thyroid hormones.
It's the four and three in the T four and
T three thyroid hormones. It supports the conversion of tirasine

(39:25):
to dopamine, improving mood, focus and motivation. It enhances acetyl
coaline for the learning and memory, lowers your cortisol dysregulation,
and supports your adrenals. Of course, it also displaces the fluoride,
the bloralmide, and the chlorine that are clogging your receptor
sites and actually dumbing you down in the brain. So

(39:47):
of course also helps with the mitochondria. Health increases atp
and we are only as healthy as our mitochondria. Next
is the accelerated gold. Gold has been known for thousands
of years to help with anxiety and depress shouldn't sleep.
It balances serotonin, dopamine and GABBA. Promotes that calm, focus
and emotional stability. And then lastly is my favorite nootropic

(40:10):
accelerated cognitiblast because not only for the focus and the
moodlift that I get immediately, but for a person with
both genes for Alzheimer's, it helps prevent dementia and Alzheimer's
and the cognitive decline. It increases BDNF for sharp recognition

(40:31):
in your neural repair and stabilizes the cortisol makes you
feel more resilient against that stress that we are talking about.
So those three are amazing to help support the mood
in along with the GABBA and with the supplements that
doctor Sher talked about. So thanks for tuning in. We
cut through the noise here and we help you take

(40:54):
charge of your health. For articles, coaching, and supplements, head
to Sarah Bantael dot com or Accelerated Health Products dot com.
Don't forget to use coupon podcast ten on your first order.
If you loved what you heard today, share this episode
with your friends hit subscribe. Who do you know that
is not stressed? Is not a little bit anxious? Right?

(41:17):
It's definitely a new pandemic. And you can find Accelerated
Health with Sarah banton Spotify, Apple, YouTube, iHeartRadio, Amazon and
over one hundred other different podcasts platforms. I'm live every Monday,
Wednesday and Friday. See you next time for another deep
dive into real health that lasts