Episode Transcript
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Speaker 1 (00:01):
You're listening to Bill Handle on demand from KFI AM
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Speaker 2 (00:08):
AM six forty handle. Here morning, everybody, I'm a little
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And then this Saturday, Neil.
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So there we go Conway Friday, Saturday, Neil and Me
(01:11):
for pasta Fon, and you'll be hearing a lot more
than that because pasta Thon is coming up December two.
All right, Well, we still have half an hour to
go before Jim Keeney comes aboard.
Speaker 1 (01:22):
So I want to talk about AI. Okay.
Speaker 2 (01:26):
AI is just something that's now in our lives in
a big, big way. We have had AI for example,
chat GPT do segments of our show and they sounded
pretty good. You know, do segments of the news, do
segments of me talking and they sounded pretty good. Now
(01:50):
there is an article in the Atlantic because it's about
a new company called Cluely. I believe that Demurow talked
about this rich and it's an artificial.
Speaker 1 (02:00):
Intelligence tool called cleuly.
Speaker 2 (02:03):
Now it advertises and says we want to cheat on everything,
and it's best suited for cheating at computer related tasks.
Speaker 1 (02:13):
I mean, the reality is really isn't about cheating. That's
just to get your attention.
Speaker 2 (02:17):
And it appears as an overlay on top of your screen. Right,
It's like a heads up display where this you have
a screen and all of a sudden you have your
your reading text on top of everything, and it is, uh,
you're looking at the conversation that you're having with someone
(02:40):
and it's helping you with the conversation. Now, they call
it the cheating on Everything program. But I mean you
can cheat obviously if you're using your computer, and you're
asking your computer while you are typing. You know, while
you're answering the questions, up comes the screen and it
ends up talking to you and will end up asking
(03:04):
you questions you ask it questions. Now here is what's
going on, because oh my god, look at the technology
and how that's going.
Speaker 1 (03:14):
To basically take over. And this was fascinating to me.
Speaker 2 (03:19):
There was an author on an article writer for Atlantic
who went ahead and tested this and had conversations with
people and on the overlay it changed the conversation. Let's
say you asked me a question I really don't know
the answer or it's too nuanced for me, and it's
(03:41):
giving me suggestions and it's telling me, here's what you say,
here's a good answer, because it's reading everything about you.
It's knowing what the conversation is about where it's going.
Speaker 1 (03:55):
The problem with that is.
Speaker 2 (03:57):
It changes how you speak, because when you're speaking to someone,
it's not just a broadcast. It's not just doing a
news broadcast, where tomorrow we easily can take Amy's broadcast,
use her voice with artificial intelligence, and outcomes Amy doing
a broadcast. We did that with me and it sounded
(04:19):
pretty good. But when you're having a conversation with someone
that is so much more nuanced, that is so much
more I would even say convoluted, because we're talking about inflection,
but very nuanced inflection. And all of a sudden you realize,
you know what, that's really not the way this person
is talking, even though you are talking. If you're influenced
(04:42):
by this and you're asking those questions, wait a sec.
You wouldn't do it that way. That's not quite the
way you would do it. Even if you would ask
that question, it would be different than what you're doing,
than what you're reading. And so we're not there yet.
As this thing is moving ahead, I did one hundred
miles an hour. This is one thing that they just
(05:05):
haven't gotten down yet. And I did a story yesterday
about Elon Musk and robotics and what Elon and mus
said the problem with robots and man, we're moving with robotics,
humanoid robotics, he said, the hand problem. You can't get
a robot to mimic what a human hand can do.
It's too complex. There are too many ways and too
(05:28):
many things that a human hand does much like and
I'm going to make the analogy to this. The way
we speak to each other is so complex, has so
many aspects to it. Some we don't even realize what
we're saying, how we're well, how we're saying it is
that we're a ways away from AI even being able
(05:52):
to do that. That's kind of nice to know that
in five years you're going to be useless. What is
that cartoon?
Speaker 1 (06:01):
Is it Wally?
Speaker 2 (06:01):
Where all those fat people are flying around on their
little scooters?
Speaker 3 (06:06):
Wow?
Speaker 1 (06:07):
Yeah, and I yeah, he does.
Speaker 2 (06:11):
And I'm looking at the cartoon. It was an animated
It was an animated film. I think Disney did it.
And everybody's on this huge spaceship right, entire populations and
they're all fat, and they're all in these little flying
saucer things and no one can move, no one can
stand up. And if you look at that, it's not horrible.
(06:32):
And when I looked at it goes That's what I
want to be. I want to sit on my ass
and just literally fly around and never get up. Ah.
The wondrous of it all. Right, Now, a word or two.
And I do enjoy talking about Trump. Uh, not my
favorite president, as you know, although I tend or try
(06:54):
to give him credit where I think credit is due.
One of the things about this president, whether you want
to give him credit or not, is he is the
most out there president we will ever see. We'll never
see anything like Donald Trump again as president. He's not
presidential in any way, which means moderate, which means being
(07:14):
careful with his words. I mean, he gets what she
gets with this president. And I'll tell you there's no
secret agenda here. We knew exactly what we were getting.
And so women reporters have a tough time with him,
and a little sampling of what the president has done.
(07:36):
And this is both on Air Force one, on the
campaign trail in the White House. So on Friday, Catherine Lucia,
White House correspondent for Bloomberg, talked about the Epstein file
and the it was, and it was a follow up question,
and the President basically pointed his finger and said, quiet, quiet, piggy, Now, you.
Speaker 1 (08:03):
Know, you know, was that presidential? Probably not?
Speaker 2 (08:09):
Remember when he called Rosie O'Donnell a big fat pig,
all right?
Speaker 1 (08:16):
I mean, is that presidential? I don't know.
Speaker 2 (08:21):
Elias Almachado, who he once called miss Piggy, happened to
be have been the winner of the nineteen ninety six
missed Universe pageant, miss Piggy uh okay. And when it
comes to Rosie O'Donnell, he just recently said, I'm thinking
of removing her American citizenship?
Speaker 1 (08:39):
Okay, how do you do that?
Speaker 2 (08:41):
He just says, He just blurts out what he wants
to say. And the problem is is that he can
be pretty misogynist.
Speaker 1 (08:49):
He can be fairly sexist.
Speaker 2 (08:51):
Yesterday, what happened in the White House reporter asked about
the what was going on with Kushogi. He had he
had Muhammed Ben Solomon in the White House, a huge
event where the President had the Crown Prince Ben Solomon.
And of course as the reporters were in there and
(09:12):
the court and the President opens up. I mean, he
lays himself wide open, and EDI has to know he's
going to be attacked because.
Speaker 1 (09:19):
That's what happens. And he still doesn't. He still allows this.
Speaker 2 (09:23):
I don't think any other president would allow stuff like
this to happen.
Speaker 1 (09:27):
He does.
Speaker 2 (09:28):
And so he was asked by ABC reporter about the
Koshogi killings or the killing of Kashogi, and the President
got very upset, Look what you're doing to my guest,
you're horrible.
Speaker 1 (09:45):
You're terrible.
Speaker 2 (09:48):
The guy just doesn't like reporters unless the reporters are
reporting positively. Now, you're not going to see him ever
attack a Fox News reporter or a NEWSMAC reporter. But
the well, sometimes he doesn't even have to attack major
(10:08):
news outlet reporters because they're all hoasters, because.
Speaker 1 (10:13):
It's all fake news.
Speaker 2 (10:15):
What fascinates me is why does he have let him
in the White House if they're lying? And in fact,
what he has done is legitimized and given credentials to
some pretty far out people, I mean, just nuts. It's
fascinating stuff. And so here's some of the things that
(10:38):
we've heard him say. Keep your voice down, that's enough
of you. Be nice, don't be threatening. And my favorite
one to Megan Kelly during the debate was there was
blood coming out of her eyes, blood coming out of
her wherever. Now, I'm going to give him a pass
(10:58):
on that one, by the way, and I'll tell you why,
because he was some for some reason, while I'll tell
you I know exactly the reason.
Speaker 1 (11:07):
But what he was quote credited for was referring.
Speaker 2 (11:11):
To her new minstrel, new Christy minstrel cycle cycle, and
that's not the case if you happen to have a Okay,
that was a reference that Newilk shook his head. There's
it's will look it up the New Christy Minstrels.
Speaker 1 (11:27):
Okay. In any case, So when he said there.
Speaker 2 (11:30):
Was blood coming out of her eyes, cleming out of wherever,
he wasn't referring to that.
Speaker 1 (11:35):
I don't think he was.
Speaker 2 (11:36):
I think he just throws those lines out there now
when he calls someone miss piggy and says shut up.
Speaker 1 (11:45):
That I believe. But he got really attacked for that one.
Speaker 2 (11:47):
And you know, from from the minute he said that,
I gave him a pass on that, saying this is
the guy just throws out words that I do not
believe he was referring to that. And that's something that
I remember during the debates. It was pretty terrific.
Speaker 1 (12:00):
It was all right, coming up.
Speaker 2 (12:03):
It's a Jim Kenney, by the way, look up the
New Christy Minstrels, a very famous rock folk group.
Speaker 1 (12:12):
Okay.
Speaker 2 (12:17):
Jim Keeney is with US doctor Jim, chief medical officers
for Dignity Saint Mary Medical Center in Long Beach.
Speaker 1 (12:24):
Good morning, Jim, Good morning mill.
Speaker 2 (12:28):
Okay, do we want to do the antidepressant story first,
because I know you think that's pretty important, or the
new flu virus.
Speaker 1 (12:34):
I'm gonna throw it to you. What do you think.
Speaker 3 (12:36):
Let's let's do the flu virus first and then we
can talk a little bit longer about the antidepressant one.
Speaker 2 (12:41):
Okay, the flu virus. I take one. Every year, I
get one. And what am I looking at this year?
Speaker 3 (12:49):
Yeah? So this year, the interesting information out is that
there is an emerging strain that they're seeing more commonly
in places like the Japan and Canada. They're already starting
to see it. It's called subclade K and it's one
of the you know, we have all those H and
N variants for influenza influenza A, and it's this is
(13:13):
the H three N two that's the one that has
what we call antigenic drift. It means that the antigens
that that's what your antibodies attack, can drift a little
bit and change so that they evade the immune system.
That's why they are frequent causes of outbreaks. And that's
why the flu is so successful as an organism, you know,
(13:35):
to reproduce and be able to evade all of our defenses,
and in this case it's it wasn't in this flu shot.
This particular strain was not known. It wasn't it wasn't included.
But it still shows that the current in the UK,
they're showing that the current flu data is about seventy
five percent effective with that influenza vaccine for children and
(13:58):
about thirty to forty percent effective against this particular strain
for adults. It's still that's not bad protection, not horrible.
And the kids are the little They're like little concentrated
vectors that are putting this stuff out. They have higher
viral loads, they excrete more virus, and they do it
for longer than adults do. So really, children are the
(14:22):
little careers for this thing that get us all sick.
Speaker 2 (14:26):
Now every year we talk about this and effectively what
medicine does. These flu baby factory vaccine manufacturers they kind
of guess which variant is coming down the pike, and
in anticipation of that, they create the vaccine.
Speaker 1 (14:43):
Do I have that right?
Speaker 3 (14:45):
Yeah? Yeah, So okay, they look in the southern hemisphere
because it's winter in the you know for us in
the summer.
Speaker 2 (14:51):
So it's something they if they guess right, then obviously
seventy eighty percent, and it's a win.
Speaker 1 (14:57):
What if the guess is just is a flu vaccine just.
Speaker 2 (15:05):
Not helpful at all? Or you get some protection no
matter what.
Speaker 3 (15:10):
Yeah, so if they guess wrong, you do get less protection,
we get a bigger outbreak, and that you could argue
then in a bigger outbreak, maybe you know that little
bit of protection is more important for you, especially if
you're one of the high risk groups like elderly, you know,
people with lung di these like emphysema, asthma, those type
(15:31):
of things, or young children. So you know, you do
get some benefit from it. It does reduce your chances
of being hospitalized or being you know, or dying from
it as well. And you know, you know, tens of
thousands of people die every year from this and are hospitalized.
And last year was a big year, was a record
(15:52):
year for a people hospitalized for the flu, and that
was with a flu that was not something new. It
was the standard what we had seen passed, and the
vaccine it didn't seem quite as effective as we hoped
it would be because it was it really wasn't a
new variant at that point. So that this year is
going to be a tough year, and they're going to
be looking at things like wastewater surveillance. COVID gave us that,
(16:15):
so now we're doing a lot better job of surveillance
and knowing. We can now know that that signal will elevate,
you know, a week or two before everybody starts showing
flu symptoms, so we'll have some early warning. Now.
Speaker 2 (16:30):
And you're thirty years in the ER, I'm assuming you've
seen more than your share of people dying of the flu.
Speaker 1 (16:37):
Do I have that right?
Speaker 3 (16:38):
Yeah? But you know, thirty years ago people stayed home
and died.
Speaker 1 (16:42):
You know, it's just so now to the er and I, Hey,
I have a question.
Speaker 2 (16:46):
You ever look at someone who's just died on you
and you say something like, hey, better you than me?
Speaker 1 (16:51):
Probably not.
Speaker 3 (16:51):
I've never done that.
Speaker 2 (16:55):
I wish i'd been a doctor, all right, Jim and
a depressants and team.
Speaker 1 (17:00):
Sexual development? Yeah, let me ask you questions.
Speaker 2 (17:04):
Uh, you know, aren't teens already pretty sexually developed?
Speaker 1 (17:09):
Sexually?
Speaker 3 (17:10):
I mean no, yeah, no, no, no, because we're talking
about their brains. We're not talking about Oh oh.
Speaker 2 (17:14):
I'm sorry because I'm trying to when when I was
a teenager, I you know, I would have screwed a
tree except for the flint splinters a tree not so anyway, Oh,
we don't have to get into that. Let's talk about
tell you please.
Speaker 3 (17:31):
Yeah. The issue, the issue here is that you know this,
this hasn't been studied very extensively in teens now. Number one, First,
I want to start by saying SSRI like like prozac
and those type of things are life saving and they
are extremely safe, unlike a lot of the other medicines
we'd use to treat severe depression. That's probably lower the
(17:52):
threshold though for people giving them out because they are
so safe. And there's a difference between a teen brain
and an adult brain. So when you're depressed as an
adult and they are, they are literally stuck in that depression.
What happens is you stop, the neuroplasticity stops, you stop
making new synaptic connections and uh, and you just kind
of get stuck in a depression. That So these work
(18:15):
very well on what we call the neuroplastic you know,
the neurotrophic hypothesis of depression. This is why when you
take prozac, it immediately elevates your serotonin, but it doesn't
work for like two to three weeks. That's because it
needs to, you know, increase connections. It needs to create
new neurons, increase synaptic connections, and it has to create
(18:38):
new memories and new processes in your brain. And that
works for an adult. But as a team that's already
happening to a very high degree. They already are extremely
you know, new tropic we call it. Their Their brain
is growing, they're they're pruning back certain connections, they're creating
new connections, and it's just going on at a very
(18:59):
high level. And now when you throw this monkey wrench
in there and you are affecting their serotonin levels, which
then affect all those things through a chemical called brain
derived neurotropic factor that's increased in this situation, we don't
really know what that does.
Speaker 1 (19:19):
Now.
Speaker 3 (19:19):
Again, I'm saying it cautiously though, because so many teens
have been helped by the SIME.
Speaker 1 (19:24):
Yes, So let me ask you this.
Speaker 2 (19:27):
The takeaway for me is that you don't give out
these psychotropic drugs. The prose acts very lightly, it takes
real depression. And where is that line?
Speaker 3 (19:40):
Yeah, I mean you're you're on the right track exactly.
So you don't want to give it out for sadness, right,
that's normal human experience. We all get sad. Sometimes there's grieving, right,
we don't we grieve When you have a loss, you
have grief, and that's a normal human experience. But sometimes
grieving turns in to a severe depression. And there's a
(20:01):
definition for you know, severe depression, and the doctors can
identify that and say, look, I mean especially once people,
when teens are feeling suicidal or so impulsive that they're
at risk for suicidal behavior, that's when this becomes life saving.
So it definitely takes a high threshold. And despite how
safe these drugs are, there's reason to really believe that
(20:25):
they are impacting because when you look at animal models,
for sure, they show that adolescent animals who are given
this have much less interest in sexual behaviors and that
type of thing. And that probably is a reflection of
your interest in bonding and connection in general. So what
(20:45):
effect may this be having on the two million teens
that are that are taking the drug in the United States? Currently?
Speaker 2 (20:52):
Okay, fair enough, Jim, We'll talk again next Wednesday, Love
and the Show with your stuff talk, I take care,
all right, We're done, guys, that's it.
Speaker 1 (21:02):
Phoene Chow. Baby, you've been listening to The Bill Handle Show.
Speaker 2 (21:06):
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