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October 30, 2025 63 mins

John McAdams shares insights on the 22 Creedmoor vs 6.5 Creedmoor informed by real world data on obtained at the range, afield, and in ballistic gel in this podcast episode. John discusses the design characteristics, performance specifications, and pros and cons of each cartridge. Plus, he also shares some details on how different 6.5 Creedmoor and 22 Creedmoor factory loads have performed on game afield.

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North Fork's 120gr & 140gr Semi-Spitzer bullets are outstanding choices for the 6.5 Creedmoor that facilitate the best possible terminal performance for the cartridges on all manner of game at ranges inside 300 yards. You can purchase both bullets directly from the North Fork web site, from MidwayUSA, or from our network of other distributors all over the world.

In this episode of The Big Game Hunting Podcast, host John McAdams discusses the 6.5 Creedmoor vs 22 Creedmoor.

John conducts a deep dive on both cartridges, shows how each cartridge was specifically designed to take advantage of modern bullets, and compares how both rounds perform in several ballistic gel tests.

John's takeaway? Both cartridges overlap in their performance in certain areas, but the 22 Creedmoor is best used for predators and medium game while the 6.5 Creedmoor is ideal for medium and big game. As you'll learn, most hunters will be served well by either one though.

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Resources

Ep 286: 30 Caliber Cartridges-The Complete Guide - Episode referenced about all the various 30 caliber cartridges (to include the 30 T/C)

Ep 351: 22 Creedmoor With Derrick Ratliff- Episode referenced comparing the 22-250 to the 22 Creedmoor

Ep 360: 22 Creedmoor vs 22-250 Remington- Episode referenced comparing the 22-250 to the 22 Creedmoor

Ep 366: Modern Cartridge Design With John Snow - Episode referenced where John Snow and I discuss Modern Cartridge Design principles

308 Winchester vs 6.5 Creedmoor - Episode referenced regarding how the 6.5 Creedmoor stacks up against the 308 Winchester

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