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June 14, 2021 77 mins

This week we will do almost a Part 2 from the last episode with Drs Dale Bredesen and Kat Toups.  In that episode, we featured recently released results data on MedArchive from a clinical trial in which 84% of 25 patients with early Alzheimer's Disease and Mild Cognitive Impairment improved with a Precision Medicine approach.  

With that in mind, we want to get another perspective from the other 2 physicians who led this ground-breaking clinical trial. This week we are joined by Doctors Ann Hathaway and Deborah Gordon.

We dive deeper into the details of testing, treatment, and people involved in this trial.

The study results (not yet available in a peer-reviewed journal) were released here

https://www.medrxiv.org/content/10.1101/2021.05.10.21256982v1.full.pdf

Precision Medicine Approach to Alzheimer's Disease: Successful Proof-of-Concept Trial

 

5:07 - how the care for the patients in the study is different from the normal protocol 

8:40 - getting the study group to work with the technology required for the study 

19:07 - some of the reasons patients were not able to be successful 

25:23 - how they helped their patients create sustainable lifestyle improvement 

34:48 - viral infections that contribute to Alzheimer's and how they approached treating that 

44:52 - why is hormone replacement so important for cognitive recovery? 

51:15 - bacterial infections that can lead to cognitive decline 

1:11:15 - criticisms they will apply to future studies 

Mark as Played

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