Can Natural Killer Cells Cause Infertility or Miscarriage?

If you’ve been diagnosed with low AMH, high FSH, diminished ovarian reserve (DOR), premature ovarian insufficiency (POI), or have experienced recurrent pregnancy loss or failed IVF, you may be wondering if natural killer (NK) cells are playing a role.

In this episode, Sarah Clark, founder of Fab Fertile, explains what NK cells are, when testing may be helpful, and why many reproductive endocrinologists dismiss it. You’ll hear how functional fertility strategies, addressing inflammation, gut health, nutrient deficiencies, and immune balance; differ from conventional medicine and can improve egg quality, implantation, and pregnancy outcomes.

We also cover what progressive fertility clinics are doing, what the research says, and how to decide if immunotherapy or intralipids are right for you.

This episode is for you if you’ve had multiple implantation failures or miscarriages, feel dismissed by “normal” test results, and want evidence-based options to support your fertility journey.

🎧 Subscribe to Get Pregnant Naturally for evidence-based guidance on functional fertility, and share this episode with anyone on their fertility journey.

Not sure where to start? Download our most popular guide:  Ultimate Guide to Getting Pregnant This Year If You Have Low AMH/High FSH it breaks everything down step by step to help you understand your options and take action

For personalized support to improve pregnancy success, book a call here.

---

TIMESTAMPS

[00:00:00] Low AMH, DOR, pregnancy loss - when to look at natural killer (NK) cells
[00:02:00] Who should consider NK cell testing (recurrent miscarriage, failed IVF, autoimmune, inflammation)
[00:04:00] Why most clinics dismiss NK testing + controversy in reproductive immunology
[00:05:00] Functional fertility view: gut health, nutrient deficiencies, inflammation, toxins
[00:06:00] Vitamin D, magnesium, and environmental exposures linked to NK cell activity

[00:07:00] Functional Fertility steps before NK testing: diet, gut health, sleep, stress
[00:08:00] Stress and nervous system dysregulation as hidden fertility disruptors
[00:09:00] Why elimination diet beats trendy diets for fertility and inflammation
[00:10:00] Functional testing: GI-MAP, minerals, B vitamins, and methylation markers

---

RESOURCES

Stop Ignoring hsCRP and the Role of Inflammation in Diminished Ovarian Reserve: https://fabfertile.com/blogs/podcasts/stop-ignoring-hscrp-and-the-role-of-inflammation-in-diminished-ovarian-reserve

How To Prevent and Reverse Autoimmune Disease and Get Pregnant: https://fabfertile.com/blogs/podcasts/how-to-prevent-and-reverse-autoimmune-disease-and-get-pregnant?_pos=4&_sid=c268f733d&_ss=r

Causes of Miscarriage Before 12 Weeks: What Most Doctors Miss:  https://fabfertile.com/blogs/podcasts/causes-of-miscarriage-before-12-weeks-what-most-doctors-miss?_pos=12&_sid=0606f25e8&_ss=r

Improving Egg Quality and Fertility: The Gut Fertility Connection for Low AMH, High FSH, and Poor Egg Quality: https://fabfertile.com/blogs/podcasts/improving-egg-quality-and-fertility-the-gut-fertility-connection-for-low-amh-high-fsh-and-poor-egg-quality?_pos=8&_sid=6da5ed9f3&_ss=r

How Reproductive Immunology Therapies Can Improve Pregnancy Outcomes with Dr. Marco Mouanness: .css-j9qmi7{display:-webkit-box;display:-webkit-flex;display:-ms-flexbox;display:flex;-webkit-flex-direction:row;-ms-flex-direction:row;flex-direction:row;font-weight:700;margin-bottom:1rem;margin-top:2.8rem;width:100%;-webkit-box-pack:start;-ms-flex-pack:start;-webkit-justify-content:start;justify-content:start;padding-left:5rem;}@media only screen and (max-width: 599px){.css-j9qmi7{padding-left:0;-webkit-box-pack:center;-ms-flex-pack:center;-webkit-justify-content:center;justify-content:center;}}.css-j9qmi7 svg{fill:#27292D;}.css-j9qmi7 .eagfbvw0{-webkit-align-items:center;-webkit-box-align:center;-ms-flex-align:center;align-items:center;color:#27292D;}