Second Trimester Loss & Low AMH: Causes, Testing, and Functional Fertility Insights

We’re diving into the top functional and conventional tests to consider after the second trimester or late pregnancy loss, especially if you’ve been diagnosed with low AMH, high FSH, diminished ovarian reserve (DOR), or premature ovarian insufficiency (POI).

If you’ve had a second trimester loss or late pregnancy loss after 20 weeks and been told “everything looks normal,”this episode is for you. We dive into what’s often overlooked in conventional care and how a functional fertility approach can help uncover underlying imbalances that impact conception, hormone health, and pregnancy outcomes.

In this episode we cover 7 categories of testing to consider after late loss especially if you have low AMH, diminished ovarian reserve, autoimmune issues, recurrent miscarriage, or unexplained infertility.

You’ll learn:

The top clotting and thrombophilia markers to test (including Factor V Leiden and antiphospholipid antibodies)

Which inflammatory and immune markers (hs-CRP, ANA, cytokines, NK cells) are often missed and why they matter

How the vaginal microbiome and hidden infections like ureaplasma can cause second-trimester loss

The role of chronic stress, adrenal hormones and the HPA axis in pregnancy outcomes

Why a comprehensive blood chemistry panel can reveal nutrient deficiencies and hormone imbalances that are missed by conventional labs

Key methylation and genetic SNPs (like MTHFR) that impact detoxification, clotting and hormone metabolism

The impact of gut health and stool testing on immune tolerance, estrogen balance and inflammation

We’ll also explain how this whole body functional lens can guide your next steps in preconception planning, whether you’re trying again naturally or preparing for IVF.

This episode is for you if:

You’ve experienced a loss after 14 weeks of pregnancy and are seeking deeper understanding and support.

You want to explore both conventional and functional medicine approaches to uncover underlying causes.

You’re looking for practical lifestyle, testing, and healing strategies to improve future pregnancy outcomes.

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TIMESTAMPS

[00:00:00] Introduction: Late term pregnancy loss overview, compassion, and what to expect in this episode
[00:02:30] Functional fertility testing for late term loss thrombophilia panel, immune markers, inflammation, and infections
[00:06:00] Stress hormones, nervous system support, and comprehensive blood chemistry for improving pregnancy outcomes

[00:09:00] Blood sugar, insulin, and comprehensive thyroid testing in pregnancy loss
[00:12:00] Genetic testing, including MTHFR mutations and the importance of body healing before conception
[00:14:30] Role of gut health, infections, and estrogen metabolism in pregnancy loss

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RESOURCES

📩 Get your free 10-day elimination diet plan! Email [e-mail] with the subject line 10 DAY to receive your guide and take the first step toward reconnecting with your fertility.

Causes of Miscarriage Before 12 Weeks: What Most Doctors Miss: https://fabfertile.com/blogs/podcasts/causes-of-miscarriage-before-12-weeks-what-most-doctors-miss

The Clotting Connection: Hidden Causes of Implantation Failure and Miscarriage: https://fabfertile.com/blogs/podcasts/the-clotting-connection-hidden-causes-of-implantation-failure-and-miscarriage

Autoimmune Roadblocks to IVF: How ANA Affects Fertility: https://fabfertile.com/blogs/podcasts/autoimmune-roadblocks-to-ivf-how-ana-affects-fertility?_pos=1&_sid=4203e92e4&_ss=r

How To Prevent and Reverse Autoimmune Disease and Get Pregnant: https://fabfertile.com/blogs/podcasts/how-to-prevent-and-reverse-autoimmune-disease-and-get-pregnant?_pos=5&_sid=a4eef3155&_ss=r

Before Your IVF Transfer, Test This First: https://fabfertile.com/blogs/podcasts/before-your-ivf-transfer-test-this-first?_pos=4&_sid=5114b4bda&_ss=r

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