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July 8, 2025 43 mins

Before he sold his company to Veradigm, Will Manidis’s Science.io developed an AI model that allowed doctors to translate mountains of medical documents into usable data to improve patient outcomes. Today Will is the SVP of AI at Veradigm, and he sits down with Nick and Beezer to discuss how AI is impacting healthcare, how we can develop health systems with better outcomes, and what the future of venture might look like when compared to traditional merchant banking.


Learn more about Sapphire Partners: sapphireventures.com/sapphire-partners

Learn more about OpenLP: openlp.vc

Learn more about Asylum Ventures: asylum.vc

Learn more about Veradigm: veradigm.com/


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CHAPTERS:

(0:00) Welcome to Origins

(2:01) Human vs. AI Content (Specifically Podcasts)

(6:18) AI And the Future of Healthcare

(17:55) Is Merchant Banking Venture’s Future?

(25:17) When Does Venture Break?

(32:42) “The Only Thing We Should Care About is the Shape of the Return Curve.”

(37:24) “The Constraint Is No Longer Capital.”

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