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March 11, 2025 66 mins

There is research suggesting that industrialization has significantly altered the composition of our gut microbiota, with certain microbial species now absent in many industrialized populations.

Given the known associations between gut microbiome diversity and health, researchers have begun investigating whether restoring lost microbial species and adopting dietary patterns similar to those of non-industrialized populations could lead to measurable health benefits.

In a newly-published study, the investigators aimed to explore whether L. reuteri could be successfully reintroduced into the microbiome through the “Restore Diet” and whether such a shift would result in improvements in key cardiometabolic and inflammatory markers.

One of the authors, Dr. Anissa Armet, is on the podcast to discuss this area and both the potential and limitations of microbiome restoration efforts.

Timestamps

  • [03:48] Interview start
  • [08:45] Understanding gut microbiome restoration
  • [11:44] Challenges in microbiome research
  • [21:03] Study design and objectives
  • [43:23] Key findings and results
  • [47:46] Future research directions
  • [01:04:04] Key ideas segment (premium-only)

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