#516: Accelerating Python Data Science at NVIDIA

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August 19, 2025 • 65 mins

Python’s data stack is getting a serious GPU turbo boost. In this episode, Ben Zaitlen from NVIDIA joins us to unpack RAPIDS, the open source toolkit that lets pandas, scikit-learn, Spark, Polars, and even NetworkX execute on GPUs. We trace the project’s origin and why NVIDIA built it in the open, then dig into the pieces that matter in practice: cuDF for DataFrames, cuML for ML, cuGraph for graphs, cuXfilter for dashboards, and friends like cuSpatial and cuSignal. We talk real speedups, how the pandas accelerator works without a rewrite, and what becomes possible when jobs that used to take hours finish in minutes. You’ll hear strategies for datasets bigger than GPU memory, scaling out with Dask or Ray, Spark acceleration, and the growing role of vector search with cuVS for AI workloads. If you know the CPU tools, this is your on-ramp to the same APIs at GPU speed.

Episode sponsors

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Talk Python Courses

Links from the show

RAPIDS: github.com/rapidsai
Example notebooks showing drop-in accelerators: github.com
Benjamin Zaitlen - LinkedIn: linkedin.com
RAPIDS Deployment Guide (Stable): docs.rapids.ai
RAPIDS cuDF API Docs (Stable): docs.rapids.ai
Asianometry YouTube Video: youtube.com
cuDF pandas Accelerator (Stable): docs.rapids.ai

Watch this episode on YouTube: youtube.com
Episode #516 deep-dive: talkpython.fm/516
Episode transcripts: talkpython.fm

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.css-15opob5{left:0;position:absolute;top:0.8rem;} All Episodes

.css-14f5ked{margin:0;word-break:break-word;display:-webkit-box;-webkit-box-orient:vertical;box-orient:vertical;-webkit-line-clamp:2;overflow:hidden;}#516: Accelerating Python Data Science at NVIDIA