2022 in Review Through a Cardiology Lens

In part 1 of their annual review, cardiologists Bob Harrington and Mike Gibson discuss in-person meetings, wearables and AI, COVID lessons for medical research, and the growth of RCTs from China.

This podcast is intended for healthcare professionals only. To read a transcript or to comment, visit

https://www.medscape.com/author/bob-harrington

COVID Therapies

Therapeutic Anticoagulation With Heparin in Noncritically Ill Patients With Covid-19

https://www.nejm.org/doi/full/10.1056/NEJMoa2105911

Effect of Intermediate/High Versus Low Dose Heparin on the Thromboembolic and Hemorrhagic Risk of Unvaccinated COVID-19 Patients in the Emergency Department

https://doi.org/10.1186/s12873-022-00668-8

Two Old Meds and a DOAC a Bust Across Range of COVID Severity: The ACT Trials

https://www.medscape.com/viewarticle/980049

Effect of Ivermectin vs Placebo on Time to Sustained Recovery in Outpatients With Mild to Moderate COVID-19: A Randomized Clinical Trial

http://jamanetwork.com/article.aspx?doi=10.1001/jama.2022.18590

FDA Halts Use of Some COVID Monoclonal Antibodies Due to Omicron

https://www.medscape.com/viewarticle/967210

CT Surgeons Rise to Challenge, Lead Way in COVID Clinical Trials

https://www.sts.org/publications/sts-news/ct-surgeons-rise-challenge-lead-way-covid-clinical-trials

What Do We Know About Long COVID: A Cardiovascular Focus

https://www.medscape.com/viewarticle/981435

COVID-19 and the Heart: Is Cardiology Ready?

https://www.medscape.com/viewarticle/969206

The Stanford RECOVER Trial

https://recovercovid.org/

The Heroes Study

https://heroesresearch.org/

Artificial Intelligence

Age and Sex Estimation Using Artificial Intelligence From Standard 12-Lead ECGs

https://doi.org/10.1161/CIRCEP.119.007284

The Heartline Study

https://www.heartline.com/about

Evolution of Single-Lead ECG for STEMI Detection Using a Deep Learning Approach

https://doi.org/10.1016/j.ijcard.2021.11.039

Recognizing a Ruler Instead of a Cancer

https://menloml.com/2020/01/11/recognizing-a-ruler-instead-of-a-cancer/

Machine Learning Did Not Beat Logistic Regression in Time Series Prediction for Severe Asthma Exacerbations

https://doi.org/10.1038/s41598-022-24909-9

A Systematic Review Shows No Performance Benefit of Machine Learning Over Logistic Regression for Clinical Prediction Models

https://doi.org/10.1016/j.jclinepi.2019.02.004.

Multinational Federated Learning Approach to Train ECG and Echocardiogram Models for Hypertrophic Cardiomyopathy Detection

https://doi.org/10.1161/circulationaha.121.058696

Detection of Hypertrophic Cardiomyopathy Using a Convolutional Neural Network-Enabled Electrocardiogram

https://doi.org/10.1016/j.jacc.2019.12.030

Here's Why We're Not Prepared for the Next Wave of Biotech Innovation (by Matthew Herper)

https://www.statnews.com/2022/11/03/why-were-not-prepared-for-next-wave-of-biotech-innovation/

RCTs from China

Bivalirudin Plus a High-Dose Infusion Versus Heparin Monotherapy in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention: A Randomised Trial

https://doi.org/10.1016/S0140-6736(22)01999-7

Chinese Herbal Medicine May Offer Benefits in STEMI: CTS-AMI

https://www.medscape.com/viewarticle/983619

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