Can Low B12 Affect Endo Related Nerve Pain and Period Pain?

Today we’re continuing with our theme of micronutrients and their impact on endo pain and period pain. Today, we’re talking about B12.

Research on the use of B12 for pain suggests that B12 can reduce chronic pain (and menstrual pain) through various methods.

Firstly, B12 can inhibit the production of the inflammatory prostaglandins which are responsible for pain and inflammation, and are found to be especially high in people with endometriosis and dysmenorrhea (which is the medical term for period pain).

Additionally, B12 plays a role in supporting nerve health and pain signally pathways, which can influence pain perception. If nerves or pain signalling pathways are comprised, this could increase pain levels. This is particularly relevant to those of us with endo who are suffering with nerve related pain due to endo on the nerves, nerve damage from surgery, leg pain, etc.

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Show notes

B12 pain benefits and endo/prostaglandin link

https://pmc.ncbi.nlm.nih.gov/articles/PMC7468922

https://pubmed.ncbi.nlm.nih.gov/30700078/

https://pmc.ncbi.nlm.nih.gov/articles/PMC10178419/

https://pubmed.ncbi.nlm.nih.gov/20511671/

B12 and endo

https://www.mdpi.com/2227-9059/11/2/450

https://pmc.ncbi.nlm.nih.gov/articles/PMC10227355

https://reproductive-health-journal.biomedcentral.com/articles/10.1186/s12978-024-01895-x

https://pmc.ncbi.nlm.nih.gov/articles/PMC5625949/

B12 and period pain

https://pmc.ncbi.nlm.nih.gov/articles/PMC10178419

https://www.researchgate.net/publication/385143175_STRESS_PHYSICAL_ACTIVITY_AND_DIETARY_INTAKE_ARE_ASSOCIATED_WITH_DYSMENORRHEA_AMONG_FEMALE_STUDENTS

B12 and period pain relief

https://pubmed.ncbi.nlm.nih.gov/30700078/

https://www.sciencedirect.com/science/article/abs/pii/S0271531700001524

https://www.researchgate.net/publication/385143175_STRESS_PHYSICAL_ACTIVITY_AND_DIETARY_INTAKE_ARE_ASSOCIATED_WITH_DYSMENORRHEA_AMONG_FEMALE_STUDENTS

Supplementation

https://www.theendobellycoach.com/podcast/low-b12-and-endo

https://www.seekinghealth.com/blogs/education/methyl-free-vs-methylated-do-you-need-a-non-methylated-supplement

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