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August 8, 2025 β€’ 5 mins

πŸš€ New in Nature: Groundbreaking study reveals how the origin of your genes β€” from mom πŸ‘©β€πŸΌ or dad πŸ‘¨β€πŸΌ β€” can push human growth πŸ“ and metabolism πŸ”₯ in opposite directions!

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🧬 Using data from 236,781 people across UK Biobank, Estonian Biobank, and MoBa, researchers uncovered 30+ parent-of-origin effects (POEs), many showing bipolar impacts β€” boosting traits when inherited from one parent, reducing them from the other.

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βš–οΈ Findings support the parental conflict hypothesis: paternal genes tend to promote growth πŸš€, while maternal genes conserve resources πŸ›‘οΈ. These insights were invisible to standard GWAS, proving the power of family-rich biobanks in unlocking hidden genetic layers.

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πŸ”— Read the paper: https://doi.org/10.1038/s41586-025-09357-5

#Genomics #GWAS #Biobanks #ParentOfOrigin #Growth #Metabolism #PrecisionMedicine

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