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August 6, 2025 โ€ข 5 mins

๐Ÿ“˜ New JAMA Review: Ovarian Cancer โ€“ From Symptoms to Survival ๐ŸŒธ

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Approximately 21,000 women are diagnosed with ovarian cancer annually in the U.S.โ€”and 80% present with advanced-stage disease.

The latest JAMA review by Caruso, Weroha, and Cliby (2025) offers a comprehensive update on:

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๐Ÿงฌ Evolving genetic insights (BRCA1/2, HRD, Lynch)

๐Ÿฉบ Diagnostic strategies beyond CA-125

๐Ÿ’Š State-of-the-art therapies: surgery, chemo, PARP inhibitors, bevacizumab

๐Ÿ“‰ Declining mortality trends due to prevention and early detection

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With clear tables, evidence-based algorithms, and nuanced discussion on fertility-sparing surgery and maintenance therapy, this is a must-read for oncologists, gynecologists, and policy advocates alike.

#JAMA #OvarianCancer #WomensHealth #Oncology #BRCA #PARPinhibitors #GeneticTesting #CancerCare #GynecologicOncology #PrecisionMedicine

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