What if your immune system, not your genetics, is the key to unlocking longevity and vitality?
In this powerful episode, Darin sits down with the legendary Dr. Jeffrey Bland, the father of functional medicine, to explore how environmental toxins, ultra-processed foods, and chronic inflammation are silently robbing us of our health—and what we can actually do about it. From angry fat to immuno-rejuvenation, this episode reveals the science and solutions behind healing from the inside out.
(00:00:00) Opening – Why functional medicine matters more than ever
(00:04:44) A legal war against toxic corporations & the real cost of chemical exposure
(00:06:09) What functional medicine actually means—explained by its founder
(00:08:00) The 4 core pillars of health: physical, metabolic, cognitive, and spiritual
(00:09:17) 300,000+ chemicals: how environmental signals hijack your genes
(00:10:34) Why chronic exposure to everyday toxins is worse than we think
(00:12:00) Neurotoxicology & immunotoxicology: the hidden fields shaping your future
(00:13:00) How low-level chemical exposure impacts mood, energy, and brain clarity
(00:14:56) Scaling solutions: where we start, and why Himalayan buckwheat matters
(00:17:23) New study: reversing immune aging by 47% in 90 days with food
(00:20:37) Why nature’s orchestration is more powerful than any isolated nutrient
(00:22:20) Bitter foods, GLP-1, and the natural way to stimulate weight loss
(00:27:23) Adaptogens explained: how plants adapt to stress—and help you do the same
(00:31:19) The danger of long-term GLP-1 drugs like Ozempic: what we don’t know yet
(00:34:07) Angry fat vs. friendly fat—how inflammation starts in your gut and spreads
(00:40:01) Santa Claus vs. Mars: the science of fat as a signaling organ
(00:41:18) The Pima vs. Tarahumara paradox: genetics, food, and diabetes
(00:44:32) The 70% processed food problem: how we’re feeding chronic disease
(00:46:14) Are we floating off the planet? A metaphor for today’s health crisis
(00:48:13) Changing the economic system through farming, soil health & food quality
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On Purpose with Jay Shetty
I’m Jay Shetty host of On Purpose the worlds #1 Mental Health podcast and I’m so grateful you found us. I started this podcast 5 years ago to invite you into conversations and workshops that are designed to help make you happier, healthier and more healed. I believe that when you (yes you) feel seen, heard and understood you’re able to deal with relationship struggles, work challenges and life’s ups and downs with more ease and grace. I interview experts, celebrities, thought leaders and athletes so that we can grow our mindset, build better habits and uncover a side of them we’ve never seen before. New episodes every Monday and Friday. Your support means the world to me and I don’t take it for granted — click the follow button and leave a review to help us spread the love with On Purpose. I can’t wait for you to listen to your first or 500th episode!