Before We Die

We couldn't finish our season without discussing Elizabeth Holmes and Theranos, Inc. Even if you aren't in the med tech industry, you probably watched the Netflix series, "The Dropout" or the HBO documentary, "The Inventor: Out for Blood in Silicon Valley." The Before We Die team chimes in and adds their insider's perspective to this unfolding story. (Encore)

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The studies on the effects of mental health and technology are out and young people are more at risk than ever before. (Encore)

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A failure analysis meeting, where 30 top surgeons came together to discuss their biggest catastrophes, was the seed that built the Jacobs Institute for Medical Innovation in Buffalo, New York. The Jacobs Institute (JI) is a multi-disciplinary vascular center that fosters collisions among professionals of different disciplines in order to develop new ideas, technologies and systems. The building itself has won numerous arch...

Sandy brings up an Austrian health device from Breatheilo.com, that uses breath to analyze the menstrual cycle during the entire month and makes recommendations to boost one's daily health. This leads to personal revelations on the part of our panel and a discussion of raspberries. (Encore)

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If you or someone you know has had a stroke, the treatment received at the hospital was very likely developed by Dr. Nick Hopkins. He has defined neurological intervention and is redefining patient flow and even how hospitals should be built. Nick has pioneered several devices and procedures by thinking outside of the box and constantly exchanging ideas with doctors and experts from different disciplines. This was also the...

Many restaurants post the calories for each dish, but it doesn’t seem to change most people’s behavior. Norwegian scientists created an app to tell you how the calories you eat affect your life expectancy. Will that change your behavior? Answer from panel: electric shocks might be better. (Encore)

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Sam Mazin asked a question in a college lecture class that launched his life's work and his company, Reflexion Medical. Reflexion Medical uses Biology-Guided Radiotherapy or BGRT to provide radiation treatment in real time. Join us to understand what all of this means. The implications for late stage cancer patients are incredibly hopeful. (Encore)

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The pandemic forced people to use telehealth — and they liked it. Now that we’ve decided to live with the pandemic, a number of states are going back to banning out-of-state doctors. Is this good because states are licensing doctors, and they should be licensed to protect the public? Or is it bad because people need access to specialists in other states? What do we do if both are true? (Encore)

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When you think of innovation, Vitamin D is not necessarily the first thing that comes to mind. But meet 92-year-old Dr. Hector DeLuca. He has spent his life researching Vitamin D and he is still finding exciting new information. Dr. DeLuca is an emeritus professor at the University of Wisconsin where he has three buildings named after him for his immense contributions and discoveries. He has made 8 drugs during his lifetim...

20-50% of all prescriptions are off-label — prescribed by doctors for conditions that the drug wasn’t approved for. Doctors don’t want to talk about off-label prescriptions because insurance companies would have an excuse not to pay for it. Are we trusting our doctors too much? Or is something more basic wrong with the system? (Encore)

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Psoriasis not only takes a toll on those who suffer from it, it can also take a toll on the inventors who find more effective treatments for it. Evan Anderson is a medical engineer who found a better way to treat this debilitating disease. He formed a company, created the product, and started to treat patients...and then things got really complicated. Join us to learn about this battle and see who won. (Encore)

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Med tech companies live or die based on approvals by the FDA. Hosts John MacMahon and Sandy Miller relate from their own experiences how previous FDA management was hard to predict and decisions often seemed erratic. This led to many companies moving their testing to Europe enabling Europe to bring new medical technologies to patients much sooner than the US. But a more effective, better informed FDA has reversed this tren...

Patients with Glioblastoma brain tumors, require more than just brain surgery. After the procedure they have a high likelihood of recurrence at the same site of the original tumor. The standard of care to slow this recurrence is a series of in-hospital radiation treatments, limiting the patient's quality of life without providing the expectation of a cure. Enter the amazing Gamma Tile -- a collagen-based tile carrying gamm...

Car T-cells are a type of white blood cell that scientists are trying to manipulate to empower the immune system in the fight against cancer, but clinical trials typically rely on the most willing population — white males, who aren’t representative of anyone other than white males. So how do you broaden the trial population to be more representative? It ain’t easy. (Encore)

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After observing numerous brain surgeries, Kate Rosenbluth asked a question to a group of neurosurgeons. When their response was, I can't believe we didn't think of that, she knew that she was onto something. Her device, the Cala Trio, is a new, non-invasive option for essential tremor. Until now, the only other options were prescription medicine or brain surgery. Follow us on Kate's journey along with CEO of Cala Health, R...

Scientists at Baylor and Stanford are researching a simple protein that may be able to reduce your caloric intake. John objects and blames the patients. The other hosts are the patients and object to John. Sandy plays the electric bike card. Craig accuses John of having a romantic notion of neurochemistry, which leads, of course, to bears.

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Lab Before Slab is the mini-pod companion to the Before We Die Podcast. These are the conversations that happen around our virtual production table when we should be doing other things. But often, these seemingly random conversations lead to interesting thoughts and topics and we wished that we recorded them. One day we did and thus, the Lab Before Slab mini-pod emerged.

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As a professor at the Stanford School of Medicine, Dr. Paul Yock wanted to find a way pay it forward. Stanford BioDesign is the result of that vision. Along with our very own Sandra Miller, they created a program that brought together problem solvers from different fields and taught them how to form cross-discipline teams identifying and solving patients' needs. The program's inception tapped into the substantial resources...

Meet Dr. Paul Yock! Dr. Yock is famous for fundamentally improving cardiac interventions over his entire career. He walks us through the basics of a heart attack and how they were treated from the time his career began to now. His Rapid Exchange (RX) catheter innovation "rapidly" became the global standard. As the treatment for heart attack evolved to include cardiac stents, he next invented a catheter to see inside the pa...