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August 18, 2025 13 mins

Anxiety, Genes, and the Methylation Puzzle: How 40% of the World Carries a Hidden Mutation


“Welcome back to Chasing Eden, the show where we rediscover health and harmony through a mix of ancient wisdom and modern science. I’m your host, Caroline Thompson. Today, we’re tackling a hidden cause of anxiety that may be affecting you—or someone you love—without you even knowing. According to human biologist Gary Brecka, up to 40% of the world’s population carries a genetic mutation that impairs how their body processes folate. It’s called the MTHFR mutation, and it can lead to a condition known as methylation deficiency.


Why does that matter? Because methylation touches almost every system in the body—from how you make neurotransmitters like serotonin and dopamine, to how you detoxify, to how calm or anxious you feel every single day. If you’ve struggled with unexplained anxiety, depression, brain fog, or fatigue… this episode could shine a light on the missing piece.


We’ll discuss the symptoms, how to test for it, and, most importantly, what difference the right supplementation can make. So stay tuned—because by the end of this episode, you’ll understand how a tiny genetic change could have massive effects on your mood, your mind, and your life.”

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