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May 7, 2025 13 mins

In a recent interview between Nirpal Virdee and Darshan Kulkarni, they discussed the ongoing shifts in the pharmaceutical industry, particularly the rise of Direct-to-Patient (DTP) models. The conversation explored how these changes are driven by the pressure to reduce drug and device costs, especially in light of new tariffs that could further escalate prices. Darshan emphasized the need for pharmaceutical companies to rethink their operational models, including cutting out intermediaries to bring down costs while still optimizing patient engagement.

The role of AI was also debated. While AI is seen as a potential tool for enhancing efficiency—particularly in areas like data collection and personalized patient care—Darshan noted that AI's impact will be limited in the short term due to concerns around transparency in decision-making. However, AI could still provide valuable opportunities, especially for on-demand answers and information retrieval.

The discussion also delved into the complexities of creating a successful DTP model. Issues like patient steering, agency problems, and the risk of false claims were highlighted as potential pitfalls that companies must navigate carefully. Darshan pointed out that this new direct-to-patient approach requires clear strategies to avoid legal issues while delivering a better patient experience.

Both Nirpal and Darshan agreed that while the pharmaceutical industry is undergoing a significant evolution, it is far from a simple trend. DTP represents a fundamental shift in how patients interact with pharma companies, and while the future is uncertain, the changes have the potential to be revolutionary—especially in terms of improving patient engagement and reducing healthcare costs.

The interview concluded with both experts emphasizing the importance of compliance and trust in these new models, with Darshan stressing that regulatory frameworks would need to adapt to these innovations in order to ensure long-term value for both patients and pharmaceutical companies.



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