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November 14, 2025 30 mins

Seth Spears is a Colorado-based entrepreneur who once taught consumers how to make their own non-toxic personal care products. He says customers valued the results but not the actual production process. "They kept asking us for ready-made versions," he told me.

So he launched Wellnesse, a direct-to-consumer brand producing all-natural self-care goods, in 2020. Toothpaste quickly became the dominant item.

In our recent conversation, Seth shared the origins of Wellnesse, the demand for holistic oral care, marketing challenges, and more.

For an edited and condensed transcript with embedded audio, see: https://www.practicalecommerce.com/natural-toothpaste-propels-wellnesse-com

For all condensed transcripts with audio, see: https://www.practicalecommerce.com/tag/podcasts

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The mission of Practical Ecommerce is to help online merchants improve their businesses. We do this with expert articles, podcasts, and webinars. We are an independent publishing company founded in 2005 and unaffiliated with any ecommerce platform or provider. https://www.practicalecommerce.com

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