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June 25, 2025 30 mins

On the 53rd episode of Enterprise AI Innovators, hosts Evan Reiser (Abnormal AI) and Saam Motamedi (Greylock Partners) talk with Sineesh Keshav, Chief Technology Officer at Prologis. With over 1.3 billion square feet under management and over 8 billion in revenue, Prologis is the world's largest logistics real estate company. In this conversation, Sineesh shares his perspective on how Prologis drove 95% company-wide adoption of generative AI through personal productivity use cases. He also discusses the future of SaaS as enterprises begin to take greater ownership of their data and AI models, and how AI is enabling a shift from static infrastructure to dynamic, self-optimizing supply chains.

Quick hits from Sineesh:

On understanding build vs. buy with AI: "If everyone has access to the latest, greatest models, which should be our assumption, then the only thing that differentiates your company is your data, and how you use it. And anything that touches proprietary data should be built internally.”

On the importance of enterprise AI strategy: "This isn't something you can afford to sit out. There's a minimum investment every company needs to make—don't skimp on licenses; don't wait to see how it shakes out. Make it accessible, find champions, and start now.”

On how AI empowers employees: "At the most basic level, it's a productivity driver. Some people use it to proofread emails, others use it to summarize a 40-page memo, or draft that memo entirely. Every employee can use it in completely different ways—and that's exactly the point.”

Recent Book Recommendation: When Breath Becomes Air by Paul Kalanithi

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Enterprise AI Innovators is a show where top technology executives share how AI is transforming the enterprise. Each episode covers the real-world applications of AI, from improving products and optimizing operations to redefining the customer experience. 

Find more great insights from technology leaders and enterprise software experts at https://www.enterprisesoftware.blog/ 

Enterprise AI Innovators is produced by Josh Meer.

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