All Episodes

August 12, 2025 41 mins

With new conversations on longevity coming up, I wanted to bring back this interview so you can revisit (or hear for the first time) the key insights that are still shaping how we think about women and aging.

Originally Published October 2023

The ovaries play a key role in overall health, not just reproduction. More scientific findings are revealing that the ovaries even influence mood, behavior, and longevity. In this episode, Dr. Jennifer Garrison from the Buck Institute for Research on Aging explains the intricate relationship between the brain and reproductive organs. She covers topics including the science of aging, the “hypothalamus pituitary gonadal axis”, menopause and health, hormone replacement therapy, and the importance of understanding ovarian function.

Dr. Jennifer Garrison is a PhD scientist and the head of a research lab at the Buck Institute, an independent institute dedicated to studying aging as a risk factor for diseases. Listen as Dr. Garrison explores how age is the primary risk factor for most chronic diseases including cardiovascular disease, cancer, and neurodegenerative diseases. 

Discussed in this episode:

  • How the brain controls female physiology, including reproductive function
  • Early menopause and POI/POF 
  • Menopause and how it relates to overall health 
  • The fascinating story women’s ovaries can tell us about aging 
  • Understanding hormones as messengers in the body
  • The impact of diet and exercise on aging and fertility 
  • How understanding the aging process can help target and treat age-related diseases
  • Hormone replacement therapy for hormonal imbalances during aging
  • Physical and emotional symptoms associated with periods, motherhood, and menopause

"If we can understand the mechanisms that underlie aging— what's causing it, what's driving it— then we can use that knowledge to target age-related diseases." — Dr. Jennifer Garrison

Related to this episode:

Mark as Played

Advertise With Us

Popular Podcasts

Stuff You Should Know
Dateline NBC

Dateline NBC

Current and classic episodes, featuring compelling true-crime mysteries, powerful documentaries and in-depth investigations. Follow now to get the latest episodes of Dateline NBC completely free, or subscribe to Dateline Premium for ad-free listening and exclusive bonus content: DatelinePremium.com

The Male Room with Dr. Jesse Mills

The Male Room with Dr. Jesse Mills

As Director of The Men’s Clinic at UCLA, Dr. Jesse Mills has spent his career helping men understand their bodies, their hormones, and their health. Now he’s bringing that expertise to The Male Room — a podcast where data-driven medicine meets common sense. Each episode separates fact from hype, science from snake oil, and gives men the tools to live longer, stronger, and happier lives. With candor, humor, and real-world experience from the exam room and the operating room, Dr. Mills breaks down the latest health headlines, dissects trends, and explains what actually works — and what doesn’t. Smart, straightforward, and entertaining, The Male Room is the show that helps men take charge of their health without the jargon.

Music, radio and podcasts, all free. Listen online or download the iHeart App.

Connect

© 2025 iHeartMedia, Inc.