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May 5, 2022 29 mins

Inflammation and Depression: From Evolutionary Understandings to the Discovery of New Treatments

In our first podcast with Dr. Andrew H. Miller, we explored links between inflammation and mental illness. But we left unanswered several key questions. Why as a species we should be so prone to inflammatory disorders? Why, from an evolutionary point of view, should inflammation so readily cause depression? In this podcast we cover these questions and more, exploring why humans have an inflammatory bias, why the link between inflammation and depression likely enhanced survival and reproduction across human evolution and why the absence of co-evolved bacteria, viruses and worms in the modern world is making both inflammation and depression worse. Finally, we turn to cutting-edge research underway in Dr. Miller’s laboratory that seeks to harness the link between inflammation and depression to create better, and more personalized, treatments for mental illness. Andrew H. Miller, MD, is the William P. Timmie Professor of Psychiatry and Behavioral Sciences at Emory University. His discoveries have played a leading role in our current understanding of immune-brain interactions relevant to mental health.

This episode is Part 2 in a two-part series.

Featuring:

Dr. Andrew Miller, William P. Timmie Professor of Psychiatry and Behavioral Sciences at Emory University

Host:

Charles Raison, Psychiatrist, Professor at the University of Wisconsin-Madison and Emory University

About Emory University's Center for the Study of Human Health:

The Emory Center for the Study of Human Health was developed to expand health knowledge and translate this knowledge to all aspects of life – for the individual and populations as a whole. The Center assembles the extraordinary faculty, researchers and thought leaders from across disciplines, departments, schools and institutions to bring this knowledge to Emory University students and inspire them to become leaders for the next generation in meeting challenges facing human health.

Follow Us:

Blog: Exploring Health
Facebook: @EmoryCSHH
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Twitter: @EmoryCSHH

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