June 26, 2023 • 37 mins
News Bites are monthly episodes where Danielle and Jeff break down important topics surrounding the field of biomedical research (and some unrelated topics).
In this News Bite edition, Jeff and Danielle discuss:
- New birth control injection for female cats
- Making experiments more natural to better understand the brain
- Wound healing ink and 3D-printed applicator pens
- Potential cause of chronic pain associated with long COVID
Links to all these stories can be found below
In this episode, we also tackle topics from tornadoes to termites and share our personal experiences with these natural disasters and the chaos that sometimes ensues. Don't miss out on this fascinating and fun-filled conversation!
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Resources & Links:
- Scientists Develop New Birth Control for Female Cats—No Surgery Necessary | Smart News| Smithsonian Magazine
- Lab mice go wild: making experiments more natural in order to decode the brain (nature.com)
- PAINTing a wound-healing ink into cuts with a 3D-printing pen - American Chemical Society (acs.org)
- Preclinical Research Deciphers the Roots of Chronic Pain in Long COVID | American Association for the Advancement of Science (AAAS)
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Transcript
Episode Transcript
Available transcripts are automatically generated. Complete accuracy is not guaranteed.
Speaker 1 (00:05):
This podcast is supported by Americans for
Medical Progress and was foundedand created through the Michael
D Hare Fellowship, awardedannually to support projects
that inform and educate thepublic about the critical role
of animal research in furtheringmedical progress.
The Fellowship honors the lateDr Michael Hare, a renowned
board-certified laboratoryanimal veterinarian who
dedicated his career toscientific and medical
(00:25):
advancements and who was deeplycommitted to animal welfare and
advocacy.
Hey, everyone, welcome into theJune edition, the Librat Chat
NewsBite episodes.
Thank you for joining us.
We got some really good content, i think, for you today.
I'm going to start off with asomewhat exciting, interesting
(00:48):
story for everyone, so staytuned in a second for that.
But just before we get intothat, just please go rate review
.
Follow us on social media.
We're basically just onInstagram and Facebook.
You can also go followDanielle's mouse page.
What's your mouse page?
Speaker 2 (01:04):
Oh gosh.
Speaker 1 (01:06):
Which has more followers than our podcast.
Speaker 2 (01:08):
all of a sudden, Little Mary, mice Mary, like
M-E-R-R-Y.
Speaker 1 (01:13):
Right, and apparently people just love looking at
fake mice.
Speaker 2 (01:18):
Hey, they're freaking adorable Okay.
Speaker 1 (01:22):
I mean, you have some pretty good shots, yeah, but it
does blow my mind that they'rejust these little stuffed mice
that are living a little fakemouse life And people love it.
Speaker 2 (01:34):
No, it's taken on Like I'm turning into like an
influencer, but like a mouseinfluencer.
I'm like, oh, my mice need morethings for their kitchen And my
mice, like my followers, wantto know what my mice are up to.
And it's like, oh my God, Ineed a reality check.
Speaker 1 (01:50):
Right, I mean maybe we should start a podcast about
the fake world of mice, a day inthe life of the mice, do they
have names?
Speaker 2 (01:58):
No no.
Speaker 1 (02:00):
Because you know this whole thing started because,
Because that would be crazy.
Speaker 2 (02:03):
No, it wouldn't be crazy.
Let me explain.
The mouse collection startedbecause when my daughter was
born we didn't need like babystuff, because she's the second
kid and we already had all thebaby stuff.
So people would be like, whatdo you want me to get?
And I'm like, oh, there's these.
Really like high quality,adorable mice, like I'd love to
have a whole family for her whenshe's old enough to have a
dollhouse, because I don't likedolls.
Dolls creep me out.
Speaker 1 (02:25):
But like But fake mice are fine.
Speaker 2 (02:27):
Yes, yep, that's exactly right.
So I wanted her to have likethis really cute, high quality,
like collectible type littlemice for her dollhouse.
And then, like a lot of myfamily members are like, oh,
look at this for your mice.
And like my mom like, sew hislittle outfits for them And like
, technically, these are for mydaughter.
But I will say like I sometimesneed a reality check because I
(02:49):
am having so much fun with themuntil she gets old enough to
have very, very tiny littleminiature things.
Speaker 1 (02:56):
And then I mean okay, have you gotten any?
Are you at the point wherepeople are like I don't know any
little fake mouse, clothing oritem companies, but are they
extending you stuff, like hey,here's some stuff?
Speaker 2 (03:08):
for your mouse family and you can promote our brand.
There are accounts out therewith these same type of mice
that have like 13,000 followersAnd like For mice.
That's Yeah.
Speaker 1 (03:18):
Fake mice, sorry.
Like real mice, like out wildmice.
I get it Like people want tosee pictures of dogs.
Speaker 2 (03:25):
No, there is like a whole community of us crazies.
No, i'll call myself crazy.
I don't know if these otherpeople know that they're crazy
but there's a whole bunch of usAnd, like, some of them have
like 13,000 followers And, like,those are the people who get
the like ooh, check out thesecute.
But yes, there are Etsycompanies that make clothing for
(03:46):
these mice.
Speaker 1 (03:46):
They have like giveaways.
Do you need that?
Yeah, are you involved ingiveaways for your mice?
Speaker 2 (03:50):
I hosted my own giveaway once because it was
super fun.
Speaker 1 (03:53):
Would you guys give away the mouse I gave?
Speaker 2 (03:55):
away like miniature kitchen stuff.
I'm never giving The mice arefamily.
I'm not giving away the mice.
Speaker 1 (04:00):
Oh, okay, they're all right Keeping together, but
like little, like kitchen Familyfirst.
Speaker 2 (04:03):
Yeah, miniature cooking stuff for a mouse
kitchen, but Do they upgradetheir kitchen?
Speaker 1 (04:09):
They did some renovations for you to get rid
of it.
Speaker 2 (04:12):
There was some really cool stuff in downtown in my
town on Main Street, and therewas like a bunch of miniature
stuff and I went like a littlelike buying crazy and I was like
I don't need all this, so Igave some away.
Speaker 1 (04:22):
Okay, genius, all right.
Well, i'm glad that that'sreally taken off for you Somehow
.
Next thing, you know you'll beat the keynote speaker at the
next convention that they have,which.
Speaker 2 (04:35):
I'm, and that would be fine with me.
I'm sorry to start with that.
Speaker 1 (04:38):
Maybe you'll create the convention.
Speaker 2 (04:39):
Well, they have miniature conventions that I've
like, all right, i've looked atthem, but they're not local
enough for me and they're likeMiniature conventions and that
everything there is miniature.
Yeah, not like just mice, butlike dollhouse miniature, like.
Speaker 1 (04:54):
How do you say?
Speaker 2 (04:55):
miniature, miniature, how do you say it?
Speaker 1 (04:59):
I just say miniature, i don't really Miniature.
There's an.
Speaker 2 (05:02):
A in there, it's a miniature.
Speaker 1 (05:04):
It's just miniature.
Speaker 2 (05:05):
Now I can't even say it.
You just said it.
Now I can't say it.
You said it the way I say itMiniature.
No, it's not miniature.
It's not miniature, it's notminiature.
Okay, here we go.
Listeners, do please commentsomewhere on the post when we
air this episode.
Miniature or miniature, that'sright Now.
(05:29):
I want to know Miniaturebecause it's mini.
Jeff, you also called a sconcea sconce, So I don't know if we
can go with your pronunciation.
You were like, yeah, theScalces.
Speaker 1 (05:47):
I believe I was asking you at the time what the
proper pronunciation was.
I don't remember, but BecauseScalces didn't seem right And so
I figured it had to be Frenchand that it was Scalces.
Speaker 2 (06:01):
The Scalces, were you like you're upgrading something
at your house or something andyou're like, oh, look at these
Scalces, yeah, we had thoselights and I was taking them out
.
That's right.
Speaker 1 (06:11):
I think that's not it .
I've never heard of thosebefore, but now I'll never
forget.
Speaker 2 (06:16):
Okay.
Speaker 1 (06:17):
We don't need anybody's input on that one.
We know the correct terminologynow, all right.
Speaker 2 (06:28):
Well, should we talk about science now?
Oh, you have a story.
What was your story?
Speaker 1 (06:32):
Well, so okay, well, i guess we'll get into it.
Speaker 2 (06:35):
You said it was you were going to start with this.
Speaker 1 (06:37):
Yeah, this we have to .
So we're in Louisiana and it'swarm and there's lots of bugs in
Louisiana, tons of bugs, andthey're bigger than anywhere
else.
Louisiana, i have declared, andmaybe not the first to declare,
but like it's basically theAustralian outback of the United
(06:57):
States, okay, okay, we have allthe poisonous snakes, all the
poisonous spiders.
Speaker 2 (07:03):
Scorpions.
Speaker 1 (07:04):
I haven't seen scorpions.
I haven't looked that up.
It wouldn't surprise me.
Okay, so we're going to be alittle talking in the background
for a minute and we're justgoing to have to deal with that.
Speaker 2 (07:13):
You have a little minion running around.
Speaker 1 (07:16):
There's a pest guy here speaking of bugs, Oh fuck.
Speaker 2 (07:18):
Yeah, Very so that is Different kind.
Speaker 1 (07:21):
Right, so termites are a thing.
Do you have to worry abouttermites?
And Virginia, i don't remember.
I don't remember getting atermite inspection.
Speaker 2 (07:31):
Yeah, you get a termite inspection, like when
you buy your house, but not likean annual thing.
Right.
Speaker 1 (07:36):
So they come out every year here.
Speaker 2 (07:37):
You have termites.
Speaker 1 (07:38):
So they came out in March.
No, they came out in March.
And then the inspectioneverything looks great.
And then the guy said like justwait, like when they swarm
you'll know.
You know and you'll see thatyou'll see them out swarming.
And so I was like okay, likewell, when's that going to
happen So I can be prepared.
They didn't get a date.
Anyways, about two weeks beforeMother's Day, i was reading a
(08:06):
story to my daughters, puttingthem down to bed, felt something
like crawling on my stomach.
Speaker 2 (08:11):
No.
Speaker 1 (08:11):
Like it was a low bug .
And so when I looked up whatthe termites are going to look
like, so I you know they looklike ants, but they have like
long wings, and it was crawlingon my stomach And I was like, oh
man, and then I just kind ofknocked it off.
You know, like all of ourcurtains are like pulled back
open, like lights are on, we'regetting ready for bed, and then
the next thing, you know,there's like 10 of them flying
(08:34):
around the light, and thenthere's 30, and then there's a
hundred.
Speaker 2 (08:38):
What in your house?
Speaker 1 (08:39):
Yep, And then my we're like we're done reading at
this point, because who canfocus?
And we go out to the hallway,like the hallway lights are on,
There's, they're everywhere.
My son's out there, Like youknow, he's like dad.
It feels like we're livingoutside right now, which it did
because they're just everywhere,Like there was probably at the
(09:01):
time we noticed the one day tothe next Yep.
So zero in the house to all of asudden there were a thousand in
the house and they startedcoming out from behind the
baseboards like crawling out.
Speaker 2 (09:14):
Oh no.
Speaker 1 (09:14):
And they were in the back.
They were there are lights, andso we turned all the lights off
.
Speaker 2 (09:19):
It's like a horror movie.
See what they say to you.
Turn the lights off and bequiet.
Speaker 1 (09:22):
Yeah, so my, my coworker, he just moved here
from Texas.
The next day I was talking tohim about it and he was putting
his daughter to bed but he wasin like a dark room already just
like doing whatever, put her tobed and he came out and his
wife is from here and he said hecame out of the room to his
(09:42):
wife like waving her arms,saying turn all the lights off,
close the windows.
They're coming.
And he was like I feel like Ineed to grab my gun, like you
know.
And so they're coming, right,they're coming.
And so then they came and theygot inside everybody's house and
(10:04):
apparently it's normal out hereand no one told me that this
happens.
Speaker 2 (10:09):
No one thought to warn you of this.
Speaker 1 (10:10):
Wait.
Speaker 2 (10:12):
So you actually stayed in your house that night.
I would have been like nopehotel, see you.
Speaker 1 (10:16):
So they last.
they fly around for a couplehours.
They came in, they can't buy it, they can't do anything.
When they land, they lose theirwings, and then they crawl and
then they just die.
Speaker 2 (10:23):
Wait what.
Speaker 1 (10:24):
By the morning time they were all dead.
Speaker 2 (10:26):
That's the stupidest life cycle.
Speaker 1 (10:28):
It was a massacre of termites inside of our house
that we then had to vacuum up.
and while I vacuum them up, i'mlike, was this just going to
repeat again tomorrow night?
Like I'm wasting all my time,so I just let this, and it
didn't happen the next night,and it hasn't happened again.
Speaker 2 (10:45):
But don't you have to worry about termites now, like
eating your foundation.
Speaker 1 (10:48):
No, i guess you don't , i don't.
Apparently they're not thetermite.
These aren't.
These are termites that, like,try to like, find and establish
new colonies, and they try tofind a mate, and then they'll
bury down in the ground together, do their thing and start a new
colony there.
So, like they swarm and they gotowards light.
Speaker 2 (11:07):
And so they've come out of the ground and by the
millions, i guess.
Speaker 1 (11:11):
They come out of the ground and they just find the
first light.
They can't fly very far, iguess, and we live in like
heavily wooded areas, so there'sobviously termites, and they
come out of the ground once ayear and try to set up, stop
somewhere else, and that was,and they thought my house would
be a good spot.
And so now we know, and they'vetold us since, like starting in
(11:31):
like mid-May, every night youjust turn all the lights off in
the front of your house, insideyour house, you close your
curtains and you're fine, theywon't come in Because the light
draws them towards you, yeah,and so they'll find a way, in no
matter what, just to come inand fly around and then die.
Speaker 2 (11:47):
And so he like he'll work here as a guy.
Close the windows, Yeah right.
Speaker 1 (11:53):
Like someone's breaking in.
It's like what's that moviewhere there's no law or rules?
Speaker 2 (11:59):
Oh, oh, they can just do it in the purge or whatever
The purge.
Speaker 1 (12:02):
Yeah, it's like the purge, except the termite
version of the purge, andthey're just finding their way
in.
Speaker 2 (12:08):
Oh, I think you've just written Disney, their next
Pixar movie Storyline.
Speaker 1 (12:12):
Yeah, and I was just upset that no one decided to
tell us about this.
Speaker 2 (12:17):
How did Claire not know, though, because she's from
there.
Speaker 1 (12:20):
I don't remember.
I don't think she remembers itlike that ever.
Speaker 2 (12:25):
Hmm, okay.
Speaker 1 (12:25):
And I think it was a particularly bad year for them
this year too.
Okay, because everyone wassaying how bad they were.
It's like, well, that better befor real thing.
Ooh, i don't have to go throughthis again, wow.
But to me, as long as theydon't actually cause any damage
and we get the inspection everyyear, there's no termites in the
house, so Yeah, yeah, whatever.
That's just hilarious though.
Yeah, i just thought his storywas funny.
(12:48):
And then apparently he turnedon his gas stove, turned all the
lights off, turned the gasstove off and they went to that
light and just burned, just hitthe flame.
Speaker 2 (12:55):
To the flame And we just started dying.
Speaker 1 (12:57):
Yeah, so that's cool.
Speaker 2 (12:59):
Yeah, ew, but then they're on your stove, okay,
well, i'm going to have to lookinto this, because that's
fascinating and disgusting.
Speaker 1 (13:07):
Yeah, so just one more thing that we have to deal
with.
Speaker 2 (13:09):
Yeah.
Speaker 1 (13:10):
And Louisiana.
Speaker 2 (13:12):
Uh, we had to deal with a tornado.
Sorry this, we are really offtopic here.
but yeah, freaking tornado, amI allowed to say freaking Um?
Speaker 1 (13:20):
driving home.
Speaker 2 (13:21):
Yeah, we were in Carrollton, if you remember this
area and like the alarm goesoff, like comes over my phone,
over the radio, everything, andlike my poor son is like mommy,
i'm scared, because it's likeseek shelter immediately.
I couldn't be like me too,buddy.
I was like no, we're okay,everything's fine.
And so I called my husband andhe was like yeah, it's bad
(13:43):
because he's like 20 minutesnorth and it was like already
there.
He's like I, you guys need tolike get somewhere.
He's like go to a grocery store, do whatever.
And I'm like there's nothingaround here, like it's just
stretches of nothingness.
Um, and I said we'll go to thelibrary because that was right
around the corner.
So we get to the libraryparking lot and librarians come
out and they're like are youreturning books?
And I'm like no, a tornadowarning just came over and I was
(14:04):
talking really fast.
And they're like okay, okay,get inside.
So we like run inside.
We were the only people at thelibrary.
We were getting ready to lockthe doors, to go into lockdown
because of the tornado warnings.
They're like if you had come aminute later, we would have been
in our break room and wewouldn't have heard you at the
door and we went into theirbreak room and then the power
went out and my poor son is like, mommy, i'm scared, i'm like no
(14:25):
, no, no, it's cool, we gotflashlights, We're fine,
everything's fine.
And the two librarians were sosweet and like, played like
Simon says, and did shadowpuppets with my kids.
And like 25 minutes later weemerge And there are just trees
down everywhere.
Speaker 1 (14:41):
Like straight up, came right through you.
Speaker 2 (14:44):
Well, you look at the news and it says confirmed
tornado in Carrollton.
Wow, like, luckily, no, youknow, there was no reported like
injuries or like issues withhuman life, but like houses lost
, some shingles and siding, andlike trees are down And it was
like, oh my goodness, like wejust drove right into that.
Speaker 1 (15:03):
That's crazy.
Speaker 2 (15:04):
So we have tornadoes and you have termites.
Speaker 1 (15:06):
We get tornadoes too, so yeah, you get everything.
But we haven't actuallyfortunately had to live through
one like you have, so that'sprobably.
I mean, it was exciting, it wasjust you and your son.
Speaker 2 (15:19):
And no, my daughter was with us too, but she thought
it was fun, she's too, shedon't care.
She was like, hmm, snacks, likeI'm in a dark room.
Speaker 1 (15:25):
Right Shadow puppets, flashlights.
Speaker 2 (15:27):
Yeah.
But, like my son could, like heunderstood that the alert was
saying like a tornado is coming,seek shelter immediately.
And he was like right, Right,that's crazy.
Yeah, no, i'll send you apicture of the clouds that were
rolling through that people weretaking, because people go
outside when these alarms go off.
Speaker 1 (15:46):
Yeah, i just watched the video online of somebody
that they were standing on theirporch as a techie Why the
tornado went by.
Yeah, you actually see thetornado, but, like they, the
camera drops for a second andthen, as it comes back up, like
all of the trees are just downin their front yard and they
were just standing outside.
Yeah, the whole time.
Yeah, so that's crazy.
Speaker 2 (16:06):
We should probably talk about science, though.
Speaker 1 (16:09):
Yeah, let's do that.
Speaker 2 (16:10):
Okay.
Speaker 1 (16:12):
That's a nice little pageant that we went on The I
have.
so I have two stories.
You have two minor about,hopefully not the same.
I have one about wound healingand then a new method to
sterilize cats, if you will.
Speaker 2 (16:32):
Okay, so I've been there.
I'm like why are we cleaningthe cats?
Speaker 1 (16:38):
But then I remember what we're talking about.
Yeah, so they can't reproduceSpain cats.
Speaker 2 (16:42):
Yeah, no, i have one.
We're talking about COVID again, but some research about kind
of looking into the chronic painfor long COVID, which is
probably good to get someinformation on, and then another
study just about moving kind ofmore into like a natural,
natural environment for animalsto like look at how their brain
(17:03):
works.
That's a really bad explanation.
It'll make more sense when Istart talking about it.
Speaker 1 (17:07):
Will it?
No, we'll try.
Okay, all right.
So this article just came out,the one that I'm going to talk
about, the new birth control forcats first, and the way that
they present it is that there'sno surgery necessary.
Once, i guess it's true and Iguess the benefit is they don't
(17:28):
have to undergo surgery.
And so for everybody out thereasking the benefit, besides
surgery, there's also over like600 million feral cats in the
United States, and that's a lot.
Oh no, i'm sorry.
The world cat population is 600million, and then they say 80%
(17:51):
of those are actually just freeroaming like feral cats, and
then, as everyone has heard,that these feral cats go out and
they kill up to like 4 billionbirds every year And that's just
in the United States in a totalof like 22 billion mammals
(18:13):
every year.
Speaker 2 (18:14):
We have cats on our property that keep taking out
birds nests And I'm getting realmad at them because I like my
little birds nests and they goin our like landscaping And I
would like to protect them.
But these cats at 3 am brutal.
Speaker 1 (18:27):
Yeah, I mean, I don't know how to get rid of those
cats, but we can hopefully atleast prevent them from breeding
and then having, and thenkeeping this cycle Right.
Going And so there's lots oflike spay neuter programs out
there.
You know, through vet school Webasically participated in that
just to get spay like surgerypractice and put the new way is
(18:50):
basically just to try to end thesurgery process of having to
capture them.
You still have to capture them.
Obviously you can't like shoota dart at them like you would
like cows out in the field.
Yeah, which that would be a funjob If you could just dart them,
just go out And anyways.
Sorry, i was talking on theroad.
So it's just an injection, thatthis is one single injection.
(19:14):
It doesn't even say whatexactly they're they're
injecting, but it takes out theneed to capture and bring them
into a clinic, undergo surgery,recover them and then bring them
basically back out to where youfound them.
Speaker 2 (19:30):
How often do they need the injection?
Speaker 1 (19:32):
Just once.
Speaker 2 (19:34):
What happens if you inject the same cat multiple
times?
Speaker 1 (19:37):
They turn into a mutant.
Yeah, i don't know.
Speaker 2 (19:42):
But like how would you know which I think they
inject?
Speaker 1 (19:44):
Well, probably the same way that you do, like spays
and neuters, you, you, you snipthem.
So, if you so, when we, when wecatch a, when a feral cat gets
caught, they spay and neuterprograms, or they're getting
neutered at a humane society orshelter.
After you spay them, you snipthe tip of the ear.
Speaker 2 (20:04):
Like an ear punch for like a mouse, so it's not
rounded anymore.
Speaker 1 (20:07):
Yeah, so it's straight across And that's like
the universal sign that this cathas already been fixed, and
same for me.
So you do that for males andfemales, because I mean,
obviously there's a way to tellif a male still intact, but
you're not getting that close tohim, so you just snip it, okay,
and so they use like antiMalarian hormone, which I guess
(20:32):
they have found that it willprotect, like ovarian reserves
and women undergoingchemotherapy.
And then researchers at Harvardand some hospital like
Massachusetts General Hospital,they did some research and
started using this, this AMHproduct, and felines, or this
(20:53):
hormone and felines, and theyshowed that they do gene therapy
with it and all this liketechnical stuff that we don't
need to get into, but they justhave to do it one time And it
doesn't.
I don't think they've studiedthem out long enough to know
like how long it would last orif it lasts you know, the entire
(21:14):
life of the cat.
Speaker 2 (21:15):
But for now, it's a non surgical sterilant.
Is this for females or males?
Just females.
Speaker 1 (21:23):
Just females, but they just females.
They brought a male cat into afemale colony for like four
month long mating trials Andthen those females did not get
pregnant.
Speaker 2 (21:41):
But you also can't snip a cat's ear unless it's
like under anesthesia.
Can you Like?
if you catch this cat, it'slike another conversation Like
if you just do the tip of theear.
Is that okay?
Speaker 1 (21:55):
I guess we have to find out how painful that is,
But also how.
Speaker 2 (21:58):
who's gonna hold that wild cat when that procedure
happens?
Speaker 1 (22:01):
Not me.
Speaker 2 (22:02):
Yeah.
Speaker 1 (22:04):
I'm not a fan of cat restraint.
Speaker 2 (22:07):
Yeah, that doesn't really work very well.
Speaker 1 (22:09):
I mean they can.
Just they're so wiggly They canget out of everything, and then
the second they get out, theirteeth are buried in your skin.
Speaker 2 (22:15):
They're coming for you, yeah.
Speaker 1 (22:19):
So looks they actually.
I'm sorry, just say that thetreatment of that hormone after
the one injection maintainedhigh levels for two years, for
over two years, and during thattime period it suppresses that
ovarian follicle development andthey can't ovulate.
So at least for two years.
Speaker 2 (22:38):
Why can't we get that ?
Speaker 1 (22:39):
like It's not longer.
Speaker 2 (22:40):
For people.
Speaker 1 (22:41):
You wanna sterilize people?
Speaker 2 (22:44):
No, but like a birth control injection that you get
once every two years, like thatsounds great.
Speaker 1 (22:49):
What?
if you want?
it has to be a reversal.
I feel like.
Speaker 2 (22:52):
True.
Speaker 1 (22:54):
You know it's gotta be some way to But like if you
know you're done having kids.
Correct.
Yeah, you know, like myself,right, i mean there are ways,
you know, i guess you can getthe injection.
That'd be easier.
There's a lot less painful.
Yeah, that's for sure.
Yeah, so I don't know.
(23:14):
It's like obviously we have away already to prevent cats from
breeding.
This I think, just kind ofhopefully, could make it more
practical that we could actuallyreduce the numbers of cats,
cause I feel like for thoseshelter veterinarians out there
that are just spaying andneutering cats all day long, i
mean you gotta feel helplesssometimes.
(23:35):
Yeah, every day Here's anothertruckload of them, yeah, and it
just never stops.
So anyways, this cool littlelike gene therapy thing that
they've done in cats And I'm notsure if they tested it
previously in mice or anything,but I think cats count as
animals on this podcast, right,so it's animal related.
Speaker 2 (23:59):
Yes, yeah.
So my first article is aboutthe roots of chronic pain in
long COVID Cause.
Chances are you probably knowsomeone, or at least know
someone who knows someone who isdealing with long COVID.
Covid is a total jerk.
I think we've beaten thatsubject to a pulp.
(24:20):
But so they started looking atthis in hamsters, giving them
COVID And the ones that werehaving like the prolonged issues
.
It reveals that the virus leftresidual genetic material in the
touch sensing neurons And sothat was triggering the long
lasting changes that wereleaving the rodents like
sensitive to pain.
And so they were kind oflooking at the neurons
(24:43):
themselves and what can be donefor it and blocking proteins and
longterm treatments.
And this article goes into alot of detail on the different
ideas.
But they're saying it's kind ofhard to translate into testing
on humans cause.
You can't easily go in and getnerves out and neurons out.
But this is just the first stepin looking towards finally
(25:07):
easing the pain, maybe finding away to get out that remaining
genetic material that COVID'sleaving behind And maybe there's
an end in sight for some ofthese people that are suffering
from it.
But they were saying apotential target for the
treatments is the protein ILF3.
And they found that anexperimental cancer drug, ym155,
(25:29):
inhibited that protein andrelieved the pain sensitivity in
a mouse model of the same issue.
So they're kind of looking atdifferent treatments, different
drugs to kind of figure out thattouch sensing neurons to kind
of ease up that longterm pain.
So again, hopefully that movesforward and those people who are
(25:51):
definitely suffering from thatget some good news soon, cause
that's COVID sucks.
Speaker 1 (25:58):
How many people like is it?
do I give you numbers Like howmany people do they think are
suffering It might have?
let me breeze through here.
Speaker 2 (26:05):
Payne, WHO sites research suggesting that as many
as 17 million people are livingwith long COVID in Europe in
2021.
Another study suggests it mightbe impacting 65 million people
worldwide, So ouch.
Speaker 1 (26:24):
And that all of those people have.
They think all those peoplehave chronic pain.
Yeah, long COVID.
Speaker 2 (26:31):
I guess they're saying if your symptoms or new
pain begins after three monthsafter you had COVID, that's sort
of what puts you in that longhaul COVID versus if you just
had a short term three months orless then you're not of the
yeah.
Speaker 1 (26:46):
And if it was just okay, all right.
Yeah, interesting, what are theso like?
any symptom you get afterhaving COVID is then classified
as long COVID.
Speaker 2 (26:58):
Chronic fatigue, pain , shortness of breath and
persistent brain fog are some ofthe although it says
encompasses more than 200reported.
Speaker 1 (27:06):
I had brain fog before COVID.
Speaker 2 (27:07):
I had brain fog as soon as I had kids.
It's still there.
Speaker 1 (27:11):
Yeah, long COVID symptoms, yeah I mean obviously
you were Difficulty thinking orconcentrating, headache, sleep
problems, dizziness when youstand up I mean, i've had that
since I was a kid.
Stand up too quick, pins andneedles, change of smell or
taste, depression or anxietyvery general.
Speaker 2 (27:27):
I mean, obviously you have to work with your doctor
to get your diagnosis, but I'mjust saying that I definitely
think sciences weren't going inthe right direction to help the
people who definitely have thatpain from COVID.
Speaker 1 (27:40):
Yeah, and I wonder if it will work for like other
things, or specifically like forCOVID, like what if you?
Speaker 2 (27:45):
have I mean, i guess, whatever, i guess What if you
have the same?
Speaker 1 (27:46):
symptoms, but you never had COVID, or you have
pain or-.
Yeah, i can just help forother-.
Maybe, Chronic types of pain orconditions?
I don't know.
Speaker 2 (27:55):
Yeah.
Cool Well progress, right Yeah.
Speaker 1 (27:59):
Progress.
All right, my next story Wereyou done, sorry.
Yes, yes, i don't know if youhave No, i don't know if you
have a whole analysis after that.
My next story is kind of cool.
It came out June 1st So, andit's from the American Chemical
Society And what this team ofresearchers developed is like a
(28:25):
wound healing ink that they canpaint onto cuts, and they paint
it on with a 3D printed pen.
So that's pretty cool.
So basically like when you geta cut on your skin or you have
some sort of abrasion or wound,you know, typically it's either
bandage, say, if it's small,just with a bandaid, or you have
(28:46):
to get like a big bandage, oryou have to get sutures or
staples or whatever you know,and then you get antibiotics to
help prevent complications fromthings getting in it and
potential infections.
And what they found out was theycould create this gel basically
(29:06):
, which is the paint, whichhelps secrete, which helps like
promote white blood cells andextracellular vesicles and
probably like fibroblasts andall this stuff to the site.
And they create a 3D pen, theyput this hydrogel based wound
healing ink inside of it Andthen they can just basically
(29:28):
paint it on And the paint standsfor portable bioactive ink for
tissue healing And so, and ituses those extracellular
vesicles and it has likemacrophages in it.
They paint it on the wound Andthey showed that in mice that
(29:48):
had they were, obviously alittle wound was created.
They put the paint solution onthere and they were almost
completely healed from a largewound.
It doesn't say what that is orhave pictures in just 12 days
And it says compared to micethat didn't receive the
treatment.
It doesn't say how far alongthey were in the healing process
(30:09):
but it says they were notnearly as far as long in the
healing process as the ones thatreceived this gel.
Speaker 2 (30:15):
I'm drawing a blank right now, but I'm trying to
think of the product name thatyou put on chickens when they
have a cut or a wound orwhatever.
We just call it the blue dye,or it's kind of purple-y, but I
can't think.
What is it called?
The blue stuff that you put onchickens.
Did you learn about the bluestuff that you put on chickens
in vet school?
We probably had a slide on it,but I don't recall To me that's
(30:35):
what I'm picturing, because it'slike blue and if you get it on
your own skin, you're going tobe blue for like two weeks.
Speaker 1 (30:42):
I hear you typing away over there.
You're trying to look it up.
No, I'm not typing.
Speaker 2 (30:46):
Oh, that's rain on the window.
Speaker 1 (30:48):
Oh, wow.
Speaker 2 (30:49):
But now I'm going to type, hold on.
Speaker 1 (30:50):
Watch out for those tornadoes.
There's the type and it'sstarted paling.
Speaker 2 (30:56):
It's called blue coat .
Blue coat for chicken wounds.
So this paint for wound healing, It's been invented for
chickens.
I'm just saying.
Speaker 1 (31:06):
Does it actually promote wound healing or is it
just prevent it from gettinginfected?
Speaker 2 (31:09):
Well, i think it just prevents it from getting
infected.
But because chickens areattracted to blood, it turns the
chicken, like the red, partblue, so that the chickens don't
see it anymore and they stoppicking at their fellow chickens
.
So it's a two for one with the-.
Speaker 1 (31:23):
Because they have for large animals and stuff.
They have that like aluminumspray, alu-sheel or Alu-spray.
And it's the same kind of thing.
You spray it on there.
Basically, you don't want fliesto get in it and everything out
there.
Speaker 2 (31:35):
Right right.
Speaker 1 (31:36):
And then you turn them into like a little robot,
like they look like they havelike a metal on them.
It's like this looks likealuminum when you spray it on,
and same kind of thing.
But I think this one is just alittle different in the fact
that it helps, like activate allof those wound healing
processes, which is a lot, youknow, complex and not worth the
(31:57):
time to get into.
And this since we've alreadyranted quite a bit on this
episode, right, right right.
But anyways, just any way tohelp.
you know, especially somebody,wounds just won't heal or they
get infected, and people dealwith chronic wound wounds that
never heal and get infected.
So this is one way to hopefullyavoid all of that And maybe
also at the same time, if youcan get it on there fast enough,
(32:19):
hopefully avoid the use ofantibiotics and then, if we're
using, less antibiotics lessresistance.
Speaker 2 (32:26):
that's good Yeah.
Speaker 1 (32:28):
So that's that.
Speaker 2 (32:30):
Cool.
My last story is just about astudy that was done Oh, i just
read the name of it over inLondon Sainsbury Welcome Center
at University University CollegeLondon.
So they're looking at sort ofthe flip side of how brains work
, because you know, you havestudies with lab mice and lab
rats where they're, you know,trained to drive a car or
(32:51):
trained to click a joystick andget a treat, and they work for
months with these animals tolike, train them on a specific
behavior and study how the brainworks.
But now they're kind of takinga step back and saying let's
look at how the brain works in amore natural setting where
maybe like a stressor isintroduced or something like
that.
So they have this little videoof a little lab mouse just
(33:12):
sniffing around a table andthere's a little shelter shed
thing off to the side, and thenall of a sudden a circle shadow
appears and starts to get bigger, as if an object's coming
closer to the table, and themouse sees the shadow, stops for
a millisecond and thenimmediately books it back to the
little shelter.
And so they're kind of lookingat what in that mouse's brain,
(33:33):
because this is a lab mouse,this isn't a mouse that's been
out there that, like nose birdsare, you know, after them.
It's not a learned behavior,It's just something that's in
them that, like you know if youhave a shadow coming and it's
not even that an object isapproaching, because it's just a
lab controlled shadow that getslarger and larger.
So they're kind of looking atmore natural stressors and how
(33:53):
the brain reacts And they thinkthat, you know, this is just the
beginning of this type ofresearch.
But what else can they do?
Can they get an owl?
Can they use a drone to havesomething approach?
And how can they study thebrain and its you know its
reaction and see how this kindof can translate to humans?
It says the end result is likestudying a professional athlete
(34:14):
The brain might work differentlyin a messy, unpredictable real
world because they have allthese other studies with very
controlled training, rewardsystem.
But this is sort of theopposite of that and kind of how
can this help translate?
for you know pain responses oryou know even conditions they're
saying might help withunderstanding Down syndrome and
autism to not look at thiscontrolled environment but more
(34:39):
of your natural, you know, messy, disorganized environment.
So kind of cool.
Speaker 1 (34:44):
It's a cute little video.
It's kind of crazy, though,that they have that natural just
instinct to something's come inand got to get out Because it's
just a shadow, especially ifthey're just lab mice, because I
mean, i remember reading aboutlike rats, a study they did with
rats and they took they werebasically like wild rats and
then they bred them and thenthey put them into a controlled
(35:05):
environment, the like you know,the offspring, to the point
where they never had toexperience any sort of like fear
or predators.
And then when they exposed, whenthey exposed them to some type
of like predator, they did havethe same response as like their,
their parents or the ones thatwere natural from the wild, and
they believe that they can passdown those kind of traits.
(35:27):
But for lab mice that are justfor generations, have just been
bred in the lab and have, youthink, no concept of that.
They don't even know thatthey're a prey species.
So that's kind of crazy.
And it goes back to cats too,backed, you know let's.
we started with cats, we'll endwith cats.
today They do the same thing,like indoor, only cats have
(35:48):
never seen outside, ever, youknow.
but they stare out that windowand they see squirrels go by and
their jaws are chattering andthey're like they start
high-pitched elevating you know,like they know they're supposed
to be out there chasing it andgetting after it.
So anyways, cool.
Well, this one rambled on for alittle while.
(36:08):
Hope everyone stuck with ustill the end and made it through
the termite story at least Youknow.
Hopefully never out there.
Speaker 2 (36:17):
Experience that until next year, but I'll let you
know if they come back.
Speaker 1 (36:20):
So please go rate, review our podcast, i mean, if
you're like going to go, ifyou're going to go check out
Danielle's little Mary mice, isthat what it is?
Speaker 2 (36:28):
Little Mary mice.
Speaker 1 (36:29):
You can check out hers too.
Boost her her followers.
Speaker 2 (36:34):
And let us know how you pronounce miniature.
Speaker 1 (36:37):
Miniature.
Yes, how you pronounceminiature, because you add a
syllable like mini, but there'san A in the word Miniature.
Say I have three, you have four, yeah, i still say miniature.
I still say the A.
Speaker 2 (36:52):
Plus, you're skipping the I Oh okay, right, miniature
.
Speaker 1 (36:58):
So yeah, let us know.
Put it in the commentssomewhere.
I guess you can remind peoplewhen you post.
once we get this episode back.
We could do a little poll.
So, anyways, i think morepeople are going to side with me
, but we'll find out, all right.
Well, thanks everyone forlistening, and we'll catch you
guys next time, see ya.
This podcast is supported by Americans for
Medical Progress and was foundedand created through the Michael
D Hare Fellowship, awardedannually to support projects
that inform and educate thepublic about the critical role
of animal research in furtheringmedical progress.
The Fellowship honors the lateDr Michael Hare, a renowned
board-certified laboratoryanimal veterinarian who
dedicated his career toscientific and medical
(00:25):
advancements and who was deeplycommitted to animal welfare and
advocacy.
Hey, everyone, welcome into theJune edition, the Librat Chat
NewsBite episodes.
Thank you for joining us.
We got some really good content, i think, for you today.
I'm going to start off with asomewhat exciting, interesting
(00:48):
story for everyone, so staytuned in a second for that.
But just before we get intothat, just please go rate review
.
Follow us on social media.
We're basically just onInstagram and Facebook.
You can also go followDanielle's mouse page.
What's your mouse page?
Speaker 2 (01:04):
Oh gosh.
Speaker 1 (01:06):
Which has more followers than our podcast.
Speaker 2 (01:08):
all of a sudden, Little Mary, mice Mary, like
M-E-R-R-Y.
Speaker 1 (01:13):
Right, and apparently people just love looking at
fake mice.
Speaker 2 (01:18):
Hey, they're freaking adorable Okay.
Speaker 1 (01:22):
I mean, you have some pretty good shots, yeah, but it
does blow my mind that they'rejust these little stuffed mice
that are living a little fakemouse life And people love it.
Speaker 2 (01:34):
No, it's taken on Like I'm turning into like an
influencer, but like a mouseinfluencer.
I'm like, oh, my mice need morethings for their kitchen And my
mice, like my followers, wantto know what my mice are up to.
And it's like, oh my God, Ineed a reality check.
Speaker 1 (01:50):
Right, I mean maybe we should start a podcast about
the fake world of mice, a day inthe life of the mice, do they
have names?
Speaker 2 (01:58):
No no.
Speaker 1 (02:00):
Because you know this whole thing started because,
Because that would be crazy.
Speaker 2 (02:03):
No, it wouldn't be crazy.
Let me explain.
The mouse collection startedbecause when my daughter was
born we didn't need like babystuff, because she's the second
kid and we already had all thebaby stuff.
So people would be like, whatdo you want me to get?
And I'm like, oh, there's these.
Really like high quality,adorable mice, like I'd love to
have a whole family for her whenshe's old enough to have a
dollhouse, because I don't likedolls.
Dolls creep me out.
Speaker 1 (02:25):
But like But fake mice are fine.
Speaker 2 (02:27):
Yes, yep, that's exactly right.
So I wanted her to have likethis really cute, high quality,
like collectible type littlemice for her dollhouse.
And then, like a lot of myfamily members are like, oh,
look at this for your mice.
And like my mom like, sew hislittle outfits for them And like
, technically, these are for mydaughter.
But I will say like I sometimesneed a reality check because I
(02:49):
am having so much fun with themuntil she gets old enough to
have very, very tiny littleminiature things.
Speaker 1 (02:56):
And then I mean okay, have you gotten any?
Are you at the point wherepeople are like I don't know any
little fake mouse, clothing oritem companies, but are they
extending you stuff, like hey,here's some stuff?
Speaker 2 (03:08):
for your mouse family and you can promote our brand.
There are accounts out therewith these same type of mice
that have like 13,000 followersAnd like For mice.
That's Yeah.
Speaker 1 (03:18):
Fake mice, sorry.
Like real mice, like out wildmice.
I get it Like people want tosee pictures of dogs.
Speaker 2 (03:25):
No, there is like a whole community of us crazies.
No, i'll call myself crazy.
I don't know if these otherpeople know that they're crazy
but there's a whole bunch of usAnd, like, some of them have
like 13,000 followers And, like,those are the people who get
the like ooh, check out thesecute.
But yes, there are Etsycompanies that make clothing for
(03:46):
these mice.
Speaker 1 (03:46):
They have like giveaways.
Do you need that?
Yeah, are you involved ingiveaways for your mice?
Speaker 2 (03:50):
I hosted my own giveaway once because it was
super fun.
Speaker 1 (03:53):
Would you guys give away the mouse I gave?
Speaker 2 (03:55):
away like miniature kitchen stuff.
I'm never giving The mice arefamily.
I'm not giving away the mice.
Speaker 1 (04:00):
Oh, okay, they're all right Keeping together, but
like little, like kitchen Familyfirst.
Speaker 2 (04:03):
Yeah, miniature cooking stuff for a mouse
kitchen, but Do they upgradetheir kitchen?
Speaker 1 (04:09):
They did some renovations for you to get rid
of it.
Speaker 2 (04:12):
There was some really cool stuff in downtown in my
town on Main Street, and therewas like a bunch of miniature
stuff and I went like a littlelike buying crazy and I was like
I don't need all this, so Igave some away.
Speaker 1 (04:22):
Okay, genius, all right.
Well, i'm glad that that'sreally taken off for you Somehow
.
Next thing, you know you'll beat the keynote speaker at the
next convention that they have,which.
Speaker 2 (04:35):
I'm, and that would be fine with me.
I'm sorry to start with that.
Speaker 1 (04:38):
Maybe you'll create the convention.
Speaker 2 (04:39):
Well, they have miniature conventions that I've
like, all right, i've looked atthem, but they're not local
enough for me and they're likeMiniature conventions and that
everything there is miniature.
Yeah, not like just mice, butlike dollhouse miniature, like.
Speaker 1 (04:54):
How do you say?
Speaker 2 (04:55):
miniature, miniature, how do you say it?
Speaker 1 (04:59):
I just say miniature, i don't really Miniature.
There's an.
Speaker 2 (05:02):
A in there, it's a miniature.
Speaker 1 (05:04):
It's just miniature.
Speaker 2 (05:05):
Now I can't even say it.
You just said it.
Now I can't say it.
You said it the way I say itMiniature.
No, it's not miniature.
It's not miniature, it's notminiature.
Okay, here we go.
Listeners, do please commentsomewhere on the post when we
air this episode.
Miniature or miniature, that'sright Now.
(05:29):
I want to know Miniaturebecause it's mini.
Jeff, you also called a sconcea sconce, So I don't know if we
can go with your pronunciation.
You were like, yeah, theScalces.
Speaker 1 (05:47):
I believe I was asking you at the time what the
proper pronunciation was.
I don't remember, but BecauseScalces didn't seem right And so
I figured it had to be Frenchand that it was Scalces.
Speaker 2 (06:01):
The Scalces, were you like you're upgrading something
at your house or something andyou're like, oh, look at these
Scalces, yeah, we had thoselights and I was taking them out
.
That's right.
Speaker 1 (06:11):
I think that's not it .
I've never heard of thosebefore, but now I'll never
forget.
Speaker 2 (06:16):
Okay.
Speaker 1 (06:17):
We don't need anybody's input on that one.
We know the correct terminologynow, all right.
Speaker 2 (06:28):
Well, should we talk about science now?
Oh, you have a story.
What was your story?
Speaker 1 (06:32):
Well, so okay, well, i guess we'll get into it.
Speaker 2 (06:35):
You said it was you were going to start with this.
Speaker 1 (06:37):
Yeah, this we have to .
So we're in Louisiana and it'swarm and there's lots of bugs in
Louisiana, tons of bugs, andthey're bigger than anywhere
else.
Louisiana, i have declared, andmaybe not the first to declare,
but like it's basically theAustralian outback of the United
(06:57):
States, okay, okay, we have allthe poisonous snakes, all the
poisonous spiders.
Speaker 2 (07:03):
Scorpions.
Speaker 1 (07:04):
I haven't seen scorpions.
I haven't looked that up.
It wouldn't surprise me.
Okay, so we're going to be alittle talking in the background
for a minute and we're justgoing to have to deal with that.
Speaker 2 (07:13):
You have a little minion running around.
Speaker 1 (07:16):
There's a pest guy here speaking of bugs, Oh fuck.
Speaker 2 (07:18):
Yeah, Very so that is Different kind.
Speaker 1 (07:21):
Right, so termites are a thing.
Do you have to worry abouttermites?
And Virginia, i don't remember.
I don't remember getting atermite inspection.
Speaker 2 (07:31):
Yeah, you get a termite inspection, like when
you buy your house, but not likean annual thing.
Right.
Speaker 1 (07:36):
So they come out every year here.
Speaker 2 (07:37):
You have termites.
Speaker 1 (07:38):
So they came out in March.
No, they came out in March.
And then the inspectioneverything looks great.
And then the guy said like justwait, like when they swarm
you'll know.
You know and you'll see thatyou'll see them out swarming.
And so I was like okay, likewell, when's that going to
happen So I can be prepared.
They didn't get a date.
Anyways, about two weeks beforeMother's Day, i was reading a
(08:06):
story to my daughters, puttingthem down to bed, felt something
like crawling on my stomach.
Speaker 2 (08:11):
No.
Speaker 1 (08:11):
Like it was a low bug .
And so when I looked up whatthe termites are going to look
like, so I you know they looklike ants, but they have like
long wings, and it was crawlingon my stomach And I was like, oh
man, and then I just kind ofknocked it off.
You know, like all of ourcurtains are like pulled back
open, like lights are on, we'regetting ready for bed, and then
the next thing, you know,there's like 10 of them flying
(08:34):
around the light, and thenthere's 30, and then there's a
hundred.
Speaker 2 (08:38):
What in your house?
Speaker 1 (08:39):
Yep, And then my we're like we're done reading at
this point, because who canfocus?
And we go out to the hallway,like the hallway lights are on,
There's, they're everywhere.
My son's out there, Like youknow, he's like dad.
It feels like we're livingoutside right now, which it did
because they're just everywhere,Like there was probably at the
(09:01):
time we noticed the one day tothe next Yep.
So zero in the house to all of asudden there were a thousand in
the house and they startedcoming out from behind the
baseboards like crawling out.
Speaker 2 (09:14):
Oh no.
Speaker 1 (09:14):
And they were in the back.
They were there are lights, andso we turned all the lights off
.
Speaker 2 (09:19):
It's like a horror movie.
See what they say to you.
Turn the lights off and bequiet.
Speaker 1 (09:22):
Yeah, so my, my coworker, he just moved here
from Texas.
The next day I was talking tohim about it and he was putting
his daughter to bed but he wasin like a dark room already just
like doing whatever, put her tobed and he came out and his
wife is from here and he said hecame out of the room to his
(09:42):
wife like waving her arms,saying turn all the lights off,
close the windows.
They're coming.
And he was like I feel like Ineed to grab my gun, like you
know.
And so they're coming, right,they're coming.
And so then they came and theygot inside everybody's house and
(10:04):
apparently it's normal out hereand no one told me that this
happens.
Speaker 2 (10:09):
No one thought to warn you of this.
Speaker 1 (10:10):
Wait.
Speaker 2 (10:12):
So you actually stayed in your house that night.
I would have been like nopehotel, see you.
Speaker 1 (10:16):
So they last.
they fly around for a couplehours.
They came in, they can't buy it, they can't do anything.
When they land, they lose theirwings, and then they crawl and
then they just die.
Speaker 2 (10:23):
Wait what.
Speaker 1 (10:24):
By the morning time they were all dead.
Speaker 2 (10:26):
That's the stupidest life cycle.
Speaker 1 (10:28):
It was a massacre of termites inside of our house
that we then had to vacuum up.
and while I vacuum them up, i'mlike, was this just going to
repeat again tomorrow night?
Like I'm wasting all my time,so I just let this, and it
didn't happen the next night,and it hasn't happened again.
Speaker 2 (10:45):
But don't you have to worry about termites now, like
eating your foundation.
Speaker 1 (10:48):
No, i guess you don't , i don't.
Apparently they're not thetermite.
These aren't.
These are termites that, like,try to like, find and establish
new colonies, and they try tofind a mate, and then they'll
bury down in the ground together, do their thing and start a new
colony there.
So, like they swarm and they gotowards light.
Speaker 2 (11:07):
And so they've come out of the ground and by the
millions, i guess.
Speaker 1 (11:11):
They come out of the ground and they just find the
first light.
They can't fly very far, iguess, and we live in like
heavily wooded areas, so there'sobviously termites, and they
come out of the ground once ayear and try to set up, stop
somewhere else, and that was,and they thought my house would
be a good spot.
And so now we know, and they'vetold us since, like starting in
(11:31):
like mid-May, every night youjust turn all the lights off in
the front of your house, insideyour house, you close your
curtains and you're fine, theywon't come in Because the light
draws them towards you, yeah,and so they'll find a way, in no
matter what, just to come inand fly around and then die.
Speaker 2 (11:47):
And so he like he'll work here as a guy.
Close the windows, Yeah right.
Speaker 1 (11:53):
Like someone's breaking in.
It's like what's that moviewhere there's no law or rules?
Speaker 2 (11:59):
Oh, oh, they can just do it in the purge or whatever
The purge.
Speaker 1 (12:02):
Yeah, it's like the purge, except the termite
version of the purge, andthey're just finding their way
in.
Speaker 2 (12:08):
Oh, I think you've just written Disney, their next
Pixar movie Storyline.
Speaker 1 (12:12):
Yeah, and I was just upset that no one decided to
tell us about this.
Speaker 2 (12:17):
How did Claire not know, though, because she's from
there.
Speaker 1 (12:20):
I don't remember.
I don't think she remembers itlike that ever.
Speaker 2 (12:25):
Hmm, okay.
Speaker 1 (12:25):
And I think it was a particularly bad year for them
this year too.
Okay, because everyone wassaying how bad they were.
It's like, well, that better befor real thing.
Ooh, i don't have to go throughthis again, wow.
But to me, as long as theydon't actually cause any damage
and we get the inspection everyyear, there's no termites in the
house, so Yeah, yeah, whatever.
That's just hilarious though.
Yeah, i just thought his storywas funny.
(12:48):
And then apparently he turnedon his gas stove, turned all the
lights off, turned the gasstove off and they went to that
light and just burned, just hitthe flame.
Speaker 2 (12:55):
To the flame And we just started dying.
Speaker 1 (12:57):
Yeah, so that's cool.
Speaker 2 (12:59):
Yeah, ew, but then they're on your stove, okay,
well, i'm going to have to lookinto this, because that's
fascinating and disgusting.
Speaker 1 (13:07):
Yeah, so just one more thing that we have to deal
with.
Speaker 2 (13:09):
Yeah.
Speaker 1 (13:10):
And Louisiana.
Speaker 2 (13:12):
Uh, we had to deal with a tornado.
Sorry this, we are really offtopic here.
but yeah, freaking tornado, amI allowed to say freaking Um?
Speaker 1 (13:20):
driving home.
Speaker 2 (13:21):
Yeah, we were in Carrollton, if you remember this
area and like the alarm goesoff, like comes over my phone,
over the radio, everything, andlike my poor son is like mommy,
i'm scared, because it's likeseek shelter immediately.
I couldn't be like me too,buddy.
I was like no, we're okay,everything's fine.
And so I called my husband andhe was like yeah, it's bad
(13:43):
because he's like 20 minutesnorth and it was like already
there.
He's like I, you guys need tolike get somewhere.
He's like go to a grocery store, do whatever.
And I'm like there's nothingaround here, like it's just
stretches of nothingness.
Um, and I said we'll go to thelibrary because that was right
around the corner.
So we get to the libraryparking lot and librarians come
out and they're like are youreturning books?
And I'm like no, a tornadowarning just came over and I was
(14:04):
talking really fast.
And they're like okay, okay,get inside.
So we like run inside.
We were the only people at thelibrary.
We were getting ready to lockthe doors, to go into lockdown
because of the tornado warnings.
They're like if you had come aminute later, we would have been
in our break room and wewouldn't have heard you at the
door and we went into theirbreak room and then the power
went out and my poor son is like, mommy, i'm scared, i'm like no
(14:25):
, no, no, it's cool, we gotflashlights, We're fine,
everything's fine.
And the two librarians were sosweet and like, played like
Simon says, and did shadowpuppets with my kids.
And like 25 minutes later weemerge And there are just trees
down everywhere.
Speaker 1 (14:41):
Like straight up, came right through you.
Speaker 2 (14:44):
Well, you look at the news and it says confirmed
tornado in Carrollton.
Wow, like, luckily, no, youknow, there was no reported like
injuries or like issues withhuman life, but like houses lost
, some shingles and siding, andlike trees are down And it was
like, oh my goodness, like wejust drove right into that.
Speaker 1 (15:03):
That's crazy.
Speaker 2 (15:04):
So we have tornadoes and you have termites.
Speaker 1 (15:06):
We get tornadoes too, so yeah, you get everything.
But we haven't actuallyfortunately had to live through
one like you have, so that'sprobably.
I mean, it was exciting, it wasjust you and your son.
Speaker 2 (15:19):
And no, my daughter was with us too, but she thought
it was fun, she's too, shedon't care.
She was like, hmm, snacks, likeI'm in a dark room.
Speaker 1 (15:25):
Right Shadow puppets, flashlights.
Speaker 2 (15:27):
Yeah.
But, like my son could, like heunderstood that the alert was
saying like a tornado is coming,seek shelter immediately.
And he was like right, Right,that's crazy.
Yeah, no, i'll send you apicture of the clouds that were
rolling through that people weretaking, because people go
outside when these alarms go off.
Speaker 1 (15:46):
Yeah, i just watched the video online of somebody
that they were standing on theirporch as a techie Why the
tornado went by.
Yeah, you actually see thetornado, but, like they, the
camera drops for a second andthen, as it comes back up, like
all of the trees are just downin their front yard and they
were just standing outside.
Yeah, the whole time.
Yeah, so that's crazy.
Speaker 2 (16:06):
We should probably talk about science, though.
Speaker 1 (16:09):
Yeah, let's do that.
Speaker 2 (16:10):
Okay.
Speaker 1 (16:12):
That's a nice little pageant that we went on The I
have.
so I have two stories.
You have two minor about,hopefully not the same.
I have one about wound healingand then a new method to
sterilize cats, if you will.
Speaker 2 (16:32):
Okay, so I've been there.
I'm like why are we cleaningthe cats?
Speaker 1 (16:38):
But then I remember what we're talking about.
Yeah, so they can't reproduceSpain cats.
Speaker 2 (16:42):
Yeah, no, i have one.
We're talking about COVID again, but some research about kind
of looking into the chronic painfor long COVID, which is
probably good to get someinformation on, and then another
study just about moving kind ofmore into like a natural,
natural environment for animalsto like look at how their brain
(17:03):
works.
That's a really bad explanation.
It'll make more sense when Istart talking about it.
Speaker 1 (17:07):
Will it?
No, we'll try.
Okay, all right.
So this article just came out,the one that I'm going to talk
about, the new birth control forcats first, and the way that
they present it is that there'sno surgery necessary.
Once, i guess it's true and Iguess the benefit is they don't
(17:28):
have to undergo surgery.
And so for everybody out thereasking the benefit, besides
surgery, there's also over like600 million feral cats in the
United States, and that's a lot.
Oh no, i'm sorry.
The world cat population is 600million, and then they say 80%
(17:51):
of those are actually just freeroaming like feral cats, and
then, as everyone has heard,that these feral cats go out and
they kill up to like 4 billionbirds every year And that's just
in the United States in a totalof like 22 billion mammals
(18:13):
every year.
Speaker 2 (18:14):
We have cats on our property that keep taking out
birds nests And I'm getting realmad at them because I like my
little birds nests and they goin our like landscaping And I
would like to protect them.
But these cats at 3 am brutal.
Speaker 1 (18:27):
Yeah, I mean, I don't know how to get rid of those
cats, but we can hopefully atleast prevent them from breeding
and then having, and thenkeeping this cycle Right.
Going And so there's lots oflike spay neuter programs out
there.
You know, through vet school Webasically participated in that
just to get spay like surgerypractice and put the new way is
(18:50):
basically just to try to end thesurgery process of having to
capture them.
You still have to capture them.
Obviously you can't like shoota dart at them like you would
like cows out in the field.
Yeah, which that would be a funjob If you could just dart them,
just go out And anyways.
Sorry, i was talking on theroad.
So it's just an injection, thatthis is one single injection.
(19:14):
It doesn't even say whatexactly they're they're
injecting, but it takes out theneed to capture and bring them
into a clinic, undergo surgery,recover them and then bring them
basically back out to where youfound them.
Speaker 2 (19:30):
How often do they need the injection?
Speaker 1 (19:32):
Just once.
Speaker 2 (19:34):
What happens if you inject the same cat multiple
times?
Speaker 1 (19:37):
They turn into a mutant.
Yeah, i don't know.
Speaker 2 (19:42):
But like how would you know which I think they
inject?
Speaker 1 (19:44):
Well, probably the same way that you do, like spays
and neuters, you, you, you snipthem.
So, if you so, when we, when wecatch a, when a feral cat gets
caught, they spay and neuterprograms, or they're getting
neutered at a humane society orshelter.
After you spay them, you snipthe tip of the ear.
Speaker 2 (20:04):
Like an ear punch for like a mouse, so it's not
rounded anymore.
Speaker 1 (20:07):
Yeah, so it's straight across And that's like
the universal sign that this cathas already been fixed, and
same for me.
So you do that for males andfemales, because I mean,
obviously there's a way to tellif a male still intact, but
you're not getting that close tohim, so you just snip it, okay,
and so they use like antiMalarian hormone, which I guess
(20:32):
they have found that it willprotect, like ovarian reserves
and women undergoingchemotherapy.
And then researchers at Harvardand some hospital like
Massachusetts General Hospital,they did some research and
started using this, this AMHproduct, and felines, or this
(20:53):
hormone and felines, and theyshowed that they do gene therapy
with it and all this liketechnical stuff that we don't
need to get into, but they justhave to do it one time And it
doesn't.
I don't think they've studiedthem out long enough to know
like how long it would last orif it lasts you know, the entire
(21:14):
life of the cat.
Speaker 2 (21:15):
But for now, it's a non surgical sterilant.
Is this for females or males?
Just females.
Speaker 1 (21:23):
Just females, but they just females.
They brought a male cat into afemale colony for like four
month long mating trials Andthen those females did not get
pregnant.
Speaker 2 (21:41):
But you also can't snip a cat's ear unless it's
like under anesthesia.
Can you Like?
if you catch this cat, it'slike another conversation Like
if you just do the tip of theear.
Is that okay?
Speaker 1 (21:55):
I guess we have to find out how painful that is,
But also how.
Speaker 2 (21:58):
who's gonna hold that wild cat when that procedure
happens?
Speaker 1 (22:01):
Not me.
Speaker 2 (22:02):
Yeah.
Speaker 1 (22:04):
I'm not a fan of cat restraint.
Speaker 2 (22:07):
Yeah, that doesn't really work very well.
Speaker 1 (22:09):
I mean they can.
Just they're so wiggly They canget out of everything, and then
the second they get out, theirteeth are buried in your skin.
Speaker 2 (22:15):
They're coming for you, yeah.
Speaker 1 (22:19):
So looks they actually.
I'm sorry, just say that thetreatment of that hormone after
the one injection maintainedhigh levels for two years, for
over two years, and during thattime period it suppresses that
ovarian follicle development andthey can't ovulate.
So at least for two years.
Speaker 2 (22:38):
Why can't we get that ?
Speaker 1 (22:39):
like It's not longer.
Speaker 2 (22:40):
For people.
Speaker 1 (22:41):
You wanna sterilize people?
Speaker 2 (22:44):
No, but like a birth control injection that you get
once every two years, like thatsounds great.
Speaker 1 (22:49):
What?
if you want?
it has to be a reversal.
I feel like.
Speaker 2 (22:52):
True.
Speaker 1 (22:54):
You know it's gotta be some way to But like if you
know you're done having kids.
Correct.
Yeah, you know, like myself,right, i mean there are ways,
you know, i guess you can getthe injection.
That'd be easier.
There's a lot less painful.
Yeah, that's for sure.
Yeah, so I don't know.
(23:14):
It's like obviously we have away already to prevent cats from
breeding.
This I think, just kind ofhopefully, could make it more
practical that we could actuallyreduce the numbers of cats,
cause I feel like for thoseshelter veterinarians out there
that are just spaying andneutering cats all day long, i
mean you gotta feel helplesssometimes.
(23:35):
Yeah, every day Here's anothertruckload of them, yeah, and it
just never stops.
So anyways, this cool littlelike gene therapy thing that
they've done in cats And I'm notsure if they tested it
previously in mice or anything,but I think cats count as
animals on this podcast, right,so it's animal related.
Speaker 2 (23:59):
Yes, yeah.
So my first article is aboutthe roots of chronic pain in
long COVID Cause.
Chances are you probably knowsomeone, or at least know
someone who knows someone who isdealing with long COVID.
Covid is a total jerk.
I think we've beaten thatsubject to a pulp.
(24:20):
But so they started looking atthis in hamsters, giving them
COVID And the ones that werehaving like the prolonged issues
.
It reveals that the virus leftresidual genetic material in the
touch sensing neurons And sothat was triggering the long
lasting changes that wereleaving the rodents like
sensitive to pain.
And so they were kind oflooking at the neurons
(24:43):
themselves and what can be donefor it and blocking proteins and
longterm treatments.
And this article goes into alot of detail on the different
ideas.
But they're saying it's kind ofhard to translate into testing
on humans cause.
You can't easily go in and getnerves out and neurons out.
But this is just the first stepin looking towards finally
(25:07):
easing the pain, maybe finding away to get out that remaining
genetic material that COVID'sleaving behind And maybe there's
an end in sight for some ofthese people that are suffering
from it.
But they were saying apotential target for the
treatments is the protein ILF3.
And they found that anexperimental cancer drug, ym155,
(25:29):
inhibited that protein andrelieved the pain sensitivity in
a mouse model of the same issue.
So they're kind of looking atdifferent treatments, different
drugs to kind of figure out thattouch sensing neurons to kind
of ease up that longterm pain.
So again, hopefully that movesforward and those people who are
(25:51):
definitely suffering from thatget some good news soon, cause
that's COVID sucks.
Speaker 1 (25:58):
How many people like is it?
do I give you numbers Like howmany people do they think are
suffering It might have?
let me breeze through here.
Speaker 2 (26:05):
Payne, WHO sites research suggesting that as many
as 17 million people are livingwith long COVID in Europe in
2021.
Another study suggests it mightbe impacting 65 million people
worldwide, So ouch.
Speaker 1 (26:24):
And that all of those people have.
They think all those peoplehave chronic pain.
Yeah, long COVID.
Speaker 2 (26:31):
I guess they're saying if your symptoms or new
pain begins after three monthsafter you had COVID, that's sort
of what puts you in that longhaul COVID versus if you just
had a short term three months orless then you're not of the
yeah.
Speaker 1 (26:46):
And if it was just okay, all right.
Yeah, interesting, what are theso like?
any symptom you get afterhaving COVID is then classified
as long COVID.
Speaker 2 (26:58):
Chronic fatigue, pain , shortness of breath and
persistent brain fog are some ofthe although it says
encompasses more than 200reported.
Speaker 1 (27:06):
I had brain fog before COVID.
Speaker 2 (27:07):
I had brain fog as soon as I had kids.
It's still there.
Speaker 1 (27:11):
Yeah, long COVID symptoms, yeah I mean obviously
you were Difficulty thinking orconcentrating, headache, sleep
problems, dizziness when youstand up I mean, i've had that
since I was a kid.
Stand up too quick, pins andneedles, change of smell or
taste, depression or anxietyvery general.
Speaker 2 (27:27):
I mean, obviously you have to work with your doctor
to get your diagnosis, but I'mjust saying that I definitely
think sciences weren't going inthe right direction to help the
people who definitely have thatpain from COVID.
Speaker 1 (27:40):
Yeah, and I wonder if it will work for like other
things, or specifically like forCOVID, like what if you?
Speaker 2 (27:45):
have I mean, i guess, whatever, i guess What if you
have the same?
Speaker 1 (27:46):
symptoms, but you never had COVID, or you have
pain or-.
Yeah, i can just help forother-.
Maybe, Chronic types of pain orconditions?
I don't know.
Speaker 2 (27:55):
Yeah.
Cool Well progress, right Yeah.
Speaker 1 (27:59):
Progress.
All right, my next story Wereyou done, sorry.
Yes, yes, i don't know if youhave No, i don't know if you
have a whole analysis after that.
My next story is kind of cool.
It came out June 1st So, andit's from the American Chemical
Society And what this team ofresearchers developed is like a
(28:25):
wound healing ink that they canpaint onto cuts, and they paint
it on with a 3D printed pen.
So that's pretty cool.
So basically like when you geta cut on your skin or you have
some sort of abrasion or wound,you know, typically it's either
bandage, say, if it's small,just with a bandaid, or you have
(28:46):
to get like a big bandage, oryou have to get sutures or
staples or whatever you know,and then you get antibiotics to
help prevent complications fromthings getting in it and
potential infections.
And what they found out was theycould create this gel basically
(29:06):
, which is the paint, whichhelps secrete, which helps like
promote white blood cells andextracellular vesicles and
probably like fibroblasts andall this stuff to the site.
And they create a 3D pen, theyput this hydrogel based wound
healing ink inside of it Andthen they can just basically
(29:28):
paint it on And the paint standsfor portable bioactive ink for
tissue healing And so, and ituses those extracellular
vesicles and it has likemacrophages in it.
They paint it on the wound Andthey showed that in mice that
(29:48):
had they were, obviously alittle wound was created.
They put the paint solution onthere and they were almost
completely healed from a largewound.
It doesn't say what that is orhave pictures in just 12 days
And it says compared to micethat didn't receive the
treatment.
It doesn't say how far alongthey were in the healing process
(30:09):
but it says they were notnearly as far as long in the
healing process as the ones thatreceived this gel.
Speaker 2 (30:15):
I'm drawing a blank right now, but I'm trying to
think of the product name thatyou put on chickens when they
have a cut or a wound orwhatever.
We just call it the blue dye,or it's kind of purple-y, but I
can't think.
What is it called?
The blue stuff that you put onchickens.
Did you learn about the bluestuff that you put on chickens
in vet school?
We probably had a slide on it,but I don't recall To me that's
(30:35):
what I'm picturing, because it'slike blue and if you get it on
your own skin, you're going tobe blue for like two weeks.
Speaker 1 (30:42):
I hear you typing away over there.
You're trying to look it up.
No, I'm not typing.
Speaker 2 (30:46):
Oh, that's rain on the window.
Speaker 1 (30:48):
Oh, wow.
Speaker 2 (30:49):
But now I'm going to type, hold on.
Speaker 1 (30:50):
Watch out for those tornadoes.
There's the type and it'sstarted paling.
Speaker 2 (30:56):
It's called blue coat .
Blue coat for chicken wounds.
So this paint for wound healing, It's been invented for
chickens.
I'm just saying.
Speaker 1 (31:06):
Does it actually promote wound healing or is it
just prevent it from gettinginfected?
Speaker 2 (31:09):
Well, i think it just prevents it from getting
infected.
But because chickens areattracted to blood, it turns the
chicken, like the red, partblue, so that the chickens don't
see it anymore and they stoppicking at their fellow chickens
.
So it's a two for one with the-.
Speaker 1 (31:23):
Because they have for large animals and stuff.
They have that like aluminumspray, alu-sheel or Alu-spray.
And it's the same kind of thing.
You spray it on there.
Basically, you don't want fliesto get in it and everything out
there.
Speaker 2 (31:35):
Right right.
Speaker 1 (31:36):
And then you turn them into like a little robot,
like they look like they havelike a metal on them.
It's like this looks likealuminum when you spray it on,
and same kind of thing.
But I think this one is just alittle different in the fact
that it helps, like activate allof those wound healing
processes, which is a lot, youknow, complex and not worth the
(31:57):
time to get into.
And this since we've alreadyranted quite a bit on this
episode, right, right right.
But anyways, just any way tohelp.
you know, especially somebody,wounds just won't heal or they
get infected, and people dealwith chronic wound wounds that
never heal and get infected.
So this is one way to hopefullyavoid all of that And maybe
also at the same time, if youcan get it on there fast enough,
(32:19):
hopefully avoid the use ofantibiotics and then, if we're
using, less antibiotics lessresistance.
Speaker 2 (32:26):
that's good Yeah.
Speaker 1 (32:28):
So that's that.
Speaker 2 (32:30):
Cool.
My last story is just about astudy that was done Oh, i just
read the name of it over inLondon Sainsbury Welcome Center
at University University CollegeLondon.
So they're looking at sort ofthe flip side of how brains work
, because you know, you havestudies with lab mice and lab
rats where they're, you know,trained to drive a car or
(32:51):
trained to click a joystick andget a treat, and they work for
months with these animals tolike, train them on a specific
behavior and study how the brainworks.
But now they're kind of takinga step back and saying let's
look at how the brain works in amore natural setting where
maybe like a stressor isintroduced or something like
that.
So they have this little videoof a little lab mouse just
(33:12):
sniffing around a table andthere's a little shelter shed
thing off to the side, and thenall of a sudden a circle shadow
appears and starts to get bigger, as if an object's coming
closer to the table, and themouse sees the shadow, stops for
a millisecond and thenimmediately books it back to the
little shelter.
And so they're kind of lookingat what in that mouse's brain,
(33:33):
because this is a lab mouse,this isn't a mouse that's been
out there that, like nose birdsare, you know, after them.
It's not a learned behavior,It's just something that's in
them that, like you know if youhave a shadow coming and it's
not even that an object isapproaching, because it's just a
lab controlled shadow that getslarger and larger.
So they're kind of looking atmore natural stressors and how
(33:53):
the brain reacts And they thinkthat, you know, this is just the
beginning of this type ofresearch.
But what else can they do?
Can they get an owl?
Can they use a drone to havesomething approach?
And how can they study thebrain and its you know its
reaction and see how this kindof can translate to humans?
It says the end result is likestudying a professional athlete
(34:14):
The brain might work differentlyin a messy, unpredictable real
world because they have allthese other studies with very
controlled training, rewardsystem.
But this is sort of theopposite of that and kind of how
can this help translate?
for you know pain responses oryou know even conditions they're
saying might help withunderstanding Down syndrome and
autism to not look at thiscontrolled environment but more
(34:39):
of your natural, you know, messy, disorganized environment.
So kind of cool.
Speaker 1 (34:44):
It's a cute little video.
It's kind of crazy, though,that they have that natural just
instinct to something's come inand got to get out Because it's
just a shadow, especially ifthey're just lab mice, because I
mean, i remember reading aboutlike rats, a study they did with
rats and they took they werebasically like wild rats and
then they bred them and thenthey put them into a controlled
(35:05):
environment, the like you know,the offspring, to the point
where they never had toexperience any sort of like fear
or predators.
And then when they exposed, whenthey exposed them to some type
of like predator, they did havethe same response as like their,
their parents or the ones thatwere natural from the wild, and
they believe that they can passdown those kind of traits.
(35:27):
But for lab mice that are justfor generations, have just been
bred in the lab and have, youthink, no concept of that.
They don't even know thatthey're a prey species.
So that's kind of crazy.
And it goes back to cats too,backed, you know let's.
we started with cats, we'll endwith cats.
today They do the same thing,like indoor, only cats have
(35:48):
never seen outside, ever, youknow.
but they stare out that windowand they see squirrels go by and
their jaws are chattering andthey're like they start
high-pitched elevating you know,like they know they're supposed
to be out there chasing it andgetting after it.
So anyways, cool.
Well, this one rambled on for alittle while.
(36:08):
Hope everyone stuck with ustill the end and made it through
the termite story at least Youknow.
Hopefully never out there.
Speaker 2 (36:17):
Experience that until next year, but I'll let you
know if they come back.
Speaker 1 (36:20):
So please go rate, review our podcast, i mean, if
you're like going to go, ifyou're going to go check out
Danielle's little Mary mice, isthat what it is?
Speaker 2 (36:28):
Little Mary mice.
Speaker 1 (36:29):
You can check out hers too.
Boost her her followers.
Speaker 2 (36:34):
And let us know how you pronounce miniature.
Speaker 1 (36:37):
Miniature.
Yes, how you pronounceminiature, because you add a
syllable like mini, but there'san A in the word Miniature.
Say I have three, you have four, yeah, i still say miniature.
I still say the A.
Speaker 2 (36:52):
Plus, you're skipping the I Oh okay, right, miniature
.
Speaker 1 (36:58):
So yeah, let us know.
Put it in the commentssomewhere.
I guess you can remind peoplewhen you post.
once we get this episode back.
We could do a little poll.
So, anyways, i think morepeople are going to side with me
, but we'll find out, all right.
Well, thanks everyone forlistening, and we'll catch you
guys next time, see ya.
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