Listen In - Bitesize Bio Webinar Audios

Liquid chromatography-mass spectrometry (LC-MS) is a crucial technique in many life sciences, including proteomics, metabolomics, pharmaceutical analysis, clinical diagnosis, and forensic science.

In this episode of Listen In, elevate your analysis and liquid chromatography. Learn what consumables, materials, and reagents can harm your LC-MS data for more accurate quantification using perfluoroalkyl substances (PFAS) as an ...

Holotomography has emerged as a helpful tool for imaging live specimens without additional pre-treatment, such as fixation, fluorescence labeling, and excitation.

It can achieve long-term three-dimensional observations of live specimens for weeks without cellular damage caused by photoactivation. The high resolution (under 150 nm lateral) achieved through synthetic numerical aperture provides sufficient spatial information...

Buffers are critical to nearly all our experiments. Poorly prepared buffers lead to failed Western blots, poor protein yields, flat binding curves—and wasted time.

Understanding why you need buffers, knowing how to choose the right one, and troubleshooting buffer issues are fundamental skills you can apply to make all your experiments work better—and you only need to learn how to prepare them correctly once.

In this episode...

You have written a research paper. What now? Your research can only have an impact if someone reads it. So, you must submit your article to a journal for publication.

In this episode of Listen In, learn the nuts and bolts of scientific publication with a step-by-step tour of the whole process. Explore how to select the right journal and what tools are available to help make that decision. Plus, get advice on how to make th...

The best way to solve a problem is to avoid it in the first place. While journals can and do reject articles for scientific reasons, they also reject articles for structural issues. By taking a few simple steps, you can learn how to circumvent these difficulties for a smooth publication process.

In this episode of Listen In, we'll go through some of the structural reasons that scientific journals reject articles, how to sol...

All research papers have certain elements in common: Introduction, Methods, Results, and Conclusion. How can you structure your introduction to best frame the research question for your readers? Must the methods section read like a laundry list of reagents? Can you be dramatic in the results without losing objectivity? Is there any room in the concluding section to pose new conflicts?

In this episode of Listen In, we will ...

Rarely do we consider writing a scientific paper as a creative exercise. But what if that could change? The best way to communicate anything is through stories. The scientific process has all the elements inherent in storytelling: a rich background, a problem or conflict to solve, and a resolution.

In this episode of Listen In, we will reframe the writing process to help you clearly and concisely communicate your research ...

Transgenic mouse models are important tools for testing therapeutic strategies. In this episode of Listen In, discover the benefits and essential considerations when characterizing and using transgenic mouse models to test therapeutic approaches to treat neurodegenerative diseases.

Plus, explore a knock-in mouse model of frontotemporal dementia that harbors a common mutation in the progranulin gene to test an antisense olig...

Explore how the latest electron microscopy techniques and volume imaging can capture fast, dynamic membrane and vesicle remodeling events during synaptic transmission at the ultrastructural level.

Neurons communicate at specialized junctions, or synapses, via chemical messengers called neurotransmitters. Within a millisecond of neuronal stimulation, synaptic vesicles packed with neurotransmitters fuse with the presynaptic p...

Experience the transformative power of unbiased, data-driven cell analysis with access to over 25 image-derived label-free parameters, empowering you to easily assess sample quality, optimize gating strategies, and validate rare events.

In this episode, learn how automated image analysis combined with flow cytometry can help improve data accuracy and precision, optimize and verify gating strategies, and discover novel biolo...

Organoids are three-dimensional in vitro cultures derived directly from patient tissues or induced pluripotent stem cells (iPSC) and embryonic stem cells. They self-organize to generate structures that resemble the tissue of origin and recapitulate the key physiological functions of the parental organ.

In this episode of Listen In, explore the benefits of organoids as infectious disease models and drug screening vehicles, ...

As a scientific researcher, you must present your work in an unbiased, original, and representative way. Without due care and attention, it is easy to drift over the boundary of what is acceptable and slip into habits that are unacceptable within the scientific community. 

This episode of Listen In with Cristy Gelling explores image manipulation. Many common types of image manipulation are classified by journals as scienti...

As a scientific researcher, you must present your work in an unbiased, original, and representative way. Without due care and attention, it is easy to drift over the boundary of what is acceptable and slip into habits that are unacceptable within the scientific community. 

This episode of Listen In with Karen O'Hanlon Cohrt explores publishing negative results and what is acceptable. Get answers to key questions, such as w...

As a scientific researcher, you must present your work in an unbiased, original, and representative way. Without due care and attention, it is easy to drift over the boundary of what is acceptable and slip into habits that are unacceptable within the scientific community.

This episode of Listen In with Karen O'Hanlon Cohrt defines plagiarism and presents some relevant statistics on this topic. She also explores self-plagia...

Eukaryotic cell cultures respond to the slightest influence. Apart from the risk of contamination, minimal changes in cultivation parameters can affect their viability, growth, and cell metabolism.

In this episode of Listen In, discover the measures you can take to improve the reproducibility of your experiments by incorporating Good Cell Culture Practice into your eukaryote culture routine.

Explore the critical aspects of ...

Many scientists see the added value in using electronic pipettes and have already upgraded their pipette fleet. The benefits include:

• Reduced strain on thumbs and arms by improving pipetting ergonomics.
• Increased reproducibility of experiments with motor-operated pipetting cycles.
• Easy and efficient handling of high sample throughput.

In this episode of Listen In, learn why switching to electronic pipettes can ...

Next-generation sequencing (NGS) has revolutionized the ‘omics’ era, with the rapid decoding of massive DNA sequences, supporting the investigation into various biological processes in human disease, genetic inheritance, immunity, cancer, and others.

But generating high-quality NGS libraries is a labor-intensive process that requires experience, precision, and accuracy. Optimal, thorough sample preparation upstream of the s...

Centrifugation is the cornerstone of lab life, used in nearly every workflow, be it a routine task like pelleting cells or a dedicated assay for an important biomolecular target.

That's why it's such a pain when they break down.

But just because we use centrifuges every day doesn't mean there aren't important technical aspects to consider or no parameters you can tailor to your specific application.

In this episode of Listen ...

Some scientific papers are unbelievable as they showcase experimental excellence that we did not think possible. These papers astound us with their groundbreaking findings and meticulous methodologies.

However, alongside these unbelievably good papers, there are papers that are unbelievable due to the pervasive presence of statistical mistakes that undermine their credibility. Whether due to negligence, lack of expertise, ...