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June 4, 2025 16 mins

This review article explores the potential benefits of creatine supplementation for brain health and function. It summarizes current research showing that creatine can increase brain creatine stores, potentially improving cognition and memory, especially under metabolic stress or in aging adults. The paper also discusses promising effects of creatine in managing symptoms associated with traumatic brain injuries, muscular dystrophies, depression, and anxiety.


Candow DG, Forbes SC, Ostojic SM, et al. "Heads Up" for Creatine Supplementation and its Potential Applications for Brain Health and Function. Sports Med. 2023;53(Suppl 1):49-65.

doi:10.1007/s40279-023-01870-9


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