Discover a groundbreaking innovation in chronic pain relief that’s redefining the future of non-opioid treatment. In this captivating episode of MedHeads,
Dr. Ferghal Armstrong interviews Samir Sabir, the founder and CEO of Brixton Biosciences, about their revolutionary new product:
Neural Ice.Designed to deliver three to six months of drug-free pain relief with a single injection, Neural Ice is an ultra-long-acting nerve block that uses a completely non-pharmaceutical, cryo-based mechanism to temporarily shut down pain-conducting nerves.
Unlike traditional methods like steroids, radiofrequency ablation (RF), or opioids, this high-tech frozen injection is simple, targeted, and potentially game-changing—especially for patients with chronic knee, hip, or thumb joint pain.
Learn how this Harvard-born technology uses cryolipolysis to induce reversible nerve desensitisation, how it bypasses the risks and complexities of RF, and why it could soon become a standard office-based procedure performed not only by pain doctors but also by orthopaedic surgeons and sports medicine specialists.
If you're looking for non-invasive, long-lasting, and clinician-friendly alternatives to steroids or surgery, this episode is a must-watch. Get the inside scoop on the clinical trials, FDA journey, and the vision for a pain-free future—without the use of opioids.
Chapters00:00 – Welcome and Introduction to Brixton Biosciences
00:45 – What Is Neural Ice and Its Purpose
02:00 – Why Samir Chose to Focus on Chronic Pain
03:30 – How the Nerve Block Works and Its Simplicity
05:00 – The Frozen Injection Mechanism Explained
07:30 – Understanding Cryolipolysis and Myelin Degeneration
10:00 – Neural Ice vs Radiofrequency Ablation (RF)
13:00 – Operator Dependence and Efficacy Compared
15:00 – Applicability for Different Nerve Types
17:00 – Competing with Steroids and HA Injections
19:00 – Injection Site and Clinician Use
21:00 – Ingredients and Engineering of Neural Ice2
4:00 – FDA Trials and Market Timeline
26:00 – Final Thoughts and Patient-Centered Mission
CrimeLess: Hillbilly Heist
It’s 1996 in rural North Carolina, and an oddball crew makes history when they pull off America’s third largest cash heist. But it’s all downhill from there. Join host Johnny Knoxville as he unspools a wild and woolly tale about a group of regular ‘ol folks who risked it all for a chance at a better life. CrimeLess: Hillbilly Heist answers the question: what would you do with 17.3 million dollars? The answer includes diamond rings, mansions, velvet Elvis paintings, plus a run for the border, murder-for-hire-plots, and FBI busts.
Crime Junkie
Does hearing about a true crime case always leave you scouring the internet for the truth behind the story? Dive into your next mystery with Crime Junkie. Every Monday, join your host Ashley Flowers as she unravels all the details of infamous and underreported true crime cases with her best friend Brit Prawat. From cold cases to missing persons and heroes in our community who seek justice, Crime Junkie is your destination for theories and stories you won’t hear anywhere else. Whether you're a seasoned true crime enthusiast or new to the genre, you'll find yourself on the edge of your seat awaiting a new episode every Monday. If you can never get enough true crime... Congratulations, you’ve found your people. Follow to join a community of Crime Junkies! Crime Junkie is presented by audiochuck Media Company.
Stuff You Should Know
If you've ever wanted to know about champagne, satanism, the Stonewall Uprising, chaos theory, LSD, El Nino, true crime and Rosa Parks, then look no further. Josh and Chuck have you covered.