Discover a groundbreaking innovation in chronic pain relief that’s redefining the future of non-opioid treatment. In this captivating episode of MedHeads,
Dr. Ferghal Armstrong interviews Samir Sabir, the founder and CEO of Brixton Biosciences, about their revolutionary new product:
Neural Ice.Designed to deliver three to six months of drug-free pain relief with a single injection, Neural Ice is an ultra-long-acting nerve block that uses a completely non-pharmaceutical, cryo-based mechanism to temporarily shut down pain-conducting nerves.
Unlike traditional methods like steroids, radiofrequency ablation (RF), or opioids, this high-tech frozen injection is simple, targeted, and potentially game-changing—especially for patients with chronic knee, hip, or thumb joint pain.
Learn how this Harvard-born technology uses cryolipolysis to induce reversible nerve desensitisation, how it bypasses the risks and complexities of RF, and why it could soon become a standard office-based procedure performed not only by pain doctors but also by orthopaedic surgeons and sports medicine specialists.
If you're looking for non-invasive, long-lasting, and clinician-friendly alternatives to steroids or surgery, this episode is a must-watch. Get the inside scoop on the clinical trials, FDA journey, and the vision for a pain-free future—without the use of opioids.
Chapters00:00 – Welcome and Introduction to Brixton Biosciences
00:45 – What Is Neural Ice and Its Purpose
02:00 – Why Samir Chose to Focus on Chronic Pain
03:30 – How the Nerve Block Works and Its Simplicity
05:00 – The Frozen Injection Mechanism Explained
07:30 – Understanding Cryolipolysis and Myelin Degeneration
10:00 – Neural Ice vs Radiofrequency Ablation (RF)
13:00 – Operator Dependence and Efficacy Compared
15:00 – Applicability for Different Nerve Types
17:00 – Competing with Steroids and HA Injections
19:00 – Injection Site and Clinician Use
21:00 – Ingredients and Engineering of Neural Ice2
4:00 – FDA Trials and Market Timeline
26:00 – Final Thoughts and Patient-Centered Mission
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Dateline NBC
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The Male Room with Dr. Jesse Mills
As Director of The Men’s Clinic at UCLA, Dr. Jesse Mills has spent his career helping men understand their bodies, their hormones, and their health. Now he’s bringing that expertise to The Male Room — a podcast where data-driven medicine meets common sense. Each episode separates fact from hype, science from snake oil, and gives men the tools to live longer, stronger, and happier lives. With candor, humor, and real-world experience from the exam room and the operating room, Dr. Mills breaks down the latest health headlines, dissects trends, and explains what actually works — and what doesn’t. Smart, straightforward, and entertaining, The Male Room is the show that helps men take charge of their health without the jargon.