Unlocking Metabolic Health Through Your Microbiome

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Episode Transcript

Speaker 1 (00:04):
Hi, how are you?
Let's talk about the gutmicrobiome and metabolic health
in our lesson two and theconnection between it.
How is that working?
So we're talking about GLP-1production, whether it's with
medication or the body itself,and what is that doing?
It becomes a critical role inregulating our metabolic health.

(00:24):
It includes secretions andfunction of glucagon-like
peptides, a hormone essentialfor blood sugar control and
appetite regulation, and insulinsensitivity.
Now what does that exactly meanand how do you have a healthy
microbiome and how does thatenhance the GLP-1 production

(00:49):
production In fermentation ofdietary fiber.
It's beneficial in the gut biomeand main ones that you'll hear
about are biphytobacteria andacromansia.
So these are fermentedprebiotics and you can get this
in prebiotic foods likevegetables, legumes, whole
grains, and those produce shortchain fatty acids, which then
will produce butyrate, acetateand propionate and that in turn

(01:13):
will help break down differentfoods and gives you the quality
amount of good and bad fiber andbody's flora within, and that
short chain fatty acids thatyou're getting in your food will
, in turn, stimulate the L cellswithin the intestine.

(01:35):
So I was talking about if youhave a good flora there, your
GLP-1 production, which producesL cells, will have uptake.
So if you don't have themedication, you don't need it
and you're eating the rightfoods and the right amount of
prebiotics and and whole foods,you're going to have more uptake

(01:57):
and promote more of that, whichthen will secrete insulin
within the body, will slow thegastric emptying which you'd
want, which then will controlyour blood sugar and reduce your
hunger.
Now we'll talk again more aboutmuscle intake here, but that's
just the gist.

(02:17):
So think then you've got yourgut and your microbiome and the
lining, the barrier, from themouth all the way down to the.
You know, through your end,that lining we want to make sure
its integrity is intact.
So they call that intestinalpermeability and making sure
that it's not impermeable, notbroken, and it's actually being

(02:39):
used.
And the junctions are, you know, the things that are supposed
to get through are getting in,and not everything.
Not the floodgates aren't open,you're just getting what needs
to get in.
Those locking keys are workingand the right nutrients are
getting in, but once thosethings in the permeability or
the integrity of that whereinflammation is causing that
wall to open, it's open and thenthe floodgates open and then

(02:59):
anything can get in, and that'swhen you have disease and
problems.
So it controls that.
So think of it like when thatis intact, you have a balanced
microbiome, you're preventingleaky gut, you're reducing
inflammation and you have properGLP-1 secretion.

(03:21):
When you do have a disconnect ora leaky gut or a dysbiosis,
you're going to have less JLPone production.
So that is also when sometimesyou'll hear someone say I've had
to uptake my medication.
Why do I have to uptake mymedication?
Well, because you may have agut health issue.
So until you address that sorry, no medication will work.

(03:47):
There will be a plateau.
So then you have to trick yourmetabolic system by eating more
whole foods, work on cleaningout the inflammation and
possibly dysbiosis or integrityof the gut health.
When you work on that and fixthe chronic inflammation or
metabolic dysfunction and reducethe inflammation, you will have

(04:08):
more of an uptick of GLP-1.
Your medications, if needed,will be there and it'll improve
your insulin sensitivity.
So that's why it comes down toreally understanding and
optimizing your body.
Now, how does the impact ofprobiotics on GLP-1s?
Now, this is because, when thestudies have shown that
lactobacillus andbifidobacterium increases GLP-1

(04:30):
secretion, yes, it leads toimproving glucose metabolism.
Also, for weight regulation,there's acromansia.
That's a big one now and thathas helped to reduce and help
with weight regulation.
Now, how does this dysbiosis umdisrupt the GLP-1.

(04:51):
I briefly had stated that inyour body when you have that
disruption or irregular good andbad microbiotic um uh
microflora within the body itwill cause it's because of poor
diet.
You're just eating processedfoods, nothing whole, no water,
and it's just sugar and junk.
You're having antibioticoveruse and chronic stress and

(05:14):
lack of sleep.
When you put all those thingstogether, you know that'll be a
factor right.
So think about that as an asimportant.
So when you reduce short chainfatty acid production which
means that you're not, you'renot eating the whole foods you
decrease your GLP-1 production.
So naturally your body is notable to do that.

(05:36):
There are some individuals thatgenetically they have low GLP-1
and in turn they have to reallybe big on what they put into
their body because they're goingto go and be more obese than
other individuals and that meansthey're with obesity but they
will have that issue of notbeing able to control their
insulin.
So there'll be other healthissues that may come up.

(06:01):
It's not as common but mostindividuals, due to this the
food intake and things that arein our bodies we will have
problems.
So that's why the gutpermeability and leaky gut is.
You know it's still importantto understand and that the the
irregularity of flora will causeinflammatory response and go
into the bloodstream.
The inflammation can causeinsulin resistance, obesity and

(06:22):
metabolic problems.
Now, when you have loweracromansia or bifactobacteria
levels, which is a probiotics,those are key players in helping
with the gut and also helpingwith regulation of your weight
control.
Some individuals are just proneto not having as much of it, so
they need it into their dietand their individuals.

(06:45):
Um, you'll see that when theyhave less GLP, one or their
other hormones start to getdysregulated, whether it's
insulin, their leptin, theirghrelin and they're going to
start to increase their cravingsand more weight gain.
In addition, we haven't eventalked about exercise in this
occasion, but you know theamount of muscle that's needed

(07:06):
to kind of bring up the uptickand getting rid of the or
regulating the insulin and theglucose within the body.
So elevated from firmacutin orbactrocytes I'm saying it a
little off, but it'sbacteriodites or firmacutes.
These are probiotics that arecommonly seen in patients.

(07:30):
They're very high in patientsthat are with obesity and that
means their ratio is higherbecause they're absorbing
they're increased volume ofcalories, processed food,
they're storing so much more fatand they're more insulin
resistant.
So I will see an uptick in thisif I did a stool testing and I

(07:51):
would see that in the personsand they're not showing enough
fatty acids.
And this can be regulated, andnot only with the medications,
but a lot of the nutrition andwhat they put into their body
and it can be improved.
But you know, until youunderstand how important gut
health is, you know I can't sitthere and tell you that.
You know these medications arethe only source or if you do it

(08:15):
naturally, you're just going tomagically get the um, get
situated.
No, you have to do a little bitof both.
Um now, how do you increase yourgut bacteria so that your
uptick is higher in the GLP-1range, so your hormones are
better, so that you can havebetter um insulin regulating?
You know insulin regulationoptimization.
You increase this by havingprebiotic fiber, eating things

(08:39):
like garlic.
Eating things like leeks,asparagus, bananas, flaxseed
oats, legumes these things thatare beneficial for stimulating
not only GLP-1, but just thebody's natural movement.
Consume fermented foods as longas it's not um causing you in a
histamine response.
Probiotic foods.

(08:59):
Eat yogurt, kefir, sauerkraut,kimchi um kombucha, as long as
you're not high inflammatoryallergy um or throat issues Um
you'll know.
If you're on a low FODMAP dietyou might need to have that
reduced um reduced foods andprocessed sugars um.
Supplements for probiotics areum lactobacillus bacterium um

(09:24):
gut health and metabolicfunction.
Um manage your sleep and stress.
You know between like seven tonine hours of sleep.
Try to get into that.
Quality, quality sleep andexercise is so paramount.
I mean this is in a range ofthings that I will talk about,
but in general um, when you umare more insulin resistant
because you're you're movingmore you're able to do and have

(09:47):
more circulation, not to mentionstrength training um and at
least some sort of muscle workto be done.
So the main things there that Ireally want you to understand
is that our body can beregulated when it's impacted by
the gut flora and when you workon your integrity of the gut

(10:10):
lining by eating the right foodsand giving it the right
nutrients.