Rejuvenating Health Over 40 With The Supplement Spermadine
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Leslie Kenny - Oxford Healthspan
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In this podcast episode of Over 40 Fitness Hacks, host Brad Williams interviews Leslie Kenny from Oxford Healthspan, diving into the topic of spermidine supplementation and its benefits, particularly for individuals over 40. Leslie, originally from Southern California but now residing in Oxford, England, shares her journey of discovering spermidine through interactions with Oxford University scientists.
Spermidine, a compound with a peculiar name, has shown promising results in rejuvenating the immune system in older individuals, helping them better combat pathogens. Leslie, a former rheumatoid arthritis patient, discusses the implications of spermidine in autoimmune conditions and cancer prevention.
The conversation shifts to the dietary sources of spermidine, with Leslie highlighting natto, a Japanese fermented soybean dish, as the highest natural source. Other sources include legumes, grains, mushrooms, and certain cheeses. However, she acknowledges that dietary restrictions such as low-carb or keto diets may limit access to spermidine-rich foods, making supplementation a viable option.
Williams expresses interest in spermidine's role in autophagy, a cellular renewal process often associated with fasting. Leslie explains how spermidine can activate autophagy even in non-fasted states, making it a valuable addition to intermittent fasting routines. She suggests taking spermidine supplements before and after fasting periods to optimize its effects.
Regarding fasting protocols, Williams inquires about the compatibility of spermidine supplements with longer fasting periods. Leslie explains that while the supplements contain minimal calories, some individuals may experience discomfort if taken on an empty stomach due to the presence of certain nutrients like B vitamins and turmeric.
The conversation concludes with advice for individuals interested in trying spermidine supplementation, emphasizing the importance of self-awareness and starting with a low dosage. Leslie shares her personal experience of incorporating spermidine into her nightly routine for better sleep quality.
Overall, the podcast provides valuable insights into spermidine supplementation and its potential benefits for individuals seeking to maintain optimal health, particularly those over 40.
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