Paris, 1961: Ram Dass gives James Fadiman a pill that changes his life. In this episode of Plantscendence, we sit down with pioneering researcher and author, Dr. James Fadiman, who is widely recognized for his groundbreaking work on microdosing psilocybin. Listeners are transported to 1961 Paris, where Dr. Fadiman recounts his initial exposure to psychedelics with his mentor, Richard Alpert (later to become Ram Dass), and the subsequent shift in his perception of reality. He tells the story of how he first came to research psychedelics at Stanford, and how these early experiments at the lab in Menlo Park eventually paved the way for him to develop the first modern microdosing protocols. The episode touches upon the historical context of entheogens, including the CIA’s covert involvement in psychedelic research and the drugs’ sudden prohibition during the Nixon era. Dr. Fadiman also reflects on recent shifts in societal attitudes towards psychedelics, and their potential to treat a variety of mental and physical illnesses.
Stuff You Should Know
If you've ever wanted to know about champagne, satanism, the Stonewall Uprising, chaos theory, LSD, El Nino, true crime and Rosa Parks, then look no further. Josh and Chuck have you covered.
Dateline NBC
Current and classic episodes, featuring compelling true-crime mysteries, powerful documentaries and in-depth investigations. Follow now to get the latest episodes of Dateline NBC completely free, or subscribe to Dateline Premium for ad-free listening and exclusive bonus content: DatelinePremium.com
The Male Room with Dr. Jesse Mills
As Director of The Men’s Clinic at UCLA, Dr. Jesse Mills has spent his career helping men understand their bodies, their hormones, and their health. Now he’s bringing that expertise to The Male Room — a podcast where data-driven medicine meets common sense. Each episode separates fact from hype, science from snake oil, and gives men the tools to live longer, stronger, and happier lives. With candor, humor, and real-world experience from the exam room and the operating room, Dr. Mills breaks down the latest health headlines, dissects trends, and explains what actually works — and what doesn’t. Smart, straightforward, and entertaining, The Male Room is the show that helps men take charge of their health without the jargon.