Possible
What if, in the future, everything breaks humanity's way? Possible is an award-winning, weekly podcast that sketches out the brightest version of the future—and what it will take to get there. Hosts Reid Hoffman and Aria Finger explore what’s possible with forward-thinking leaders, deep thinkers, and ambitious builders across many fields, such as technology, art, education and healthcare. These conversations center on the ways technology—and, in particular, AI—is shaping the future. In episodes, AI tools such as OpenAI’s GPT-4 and Inflection’s Pi are at work, offering informational asides, prompting guests, or demoing what they can do. Lastly, between guest episodes, Aria interviews her co-host Reid on his latest takes on what’s possible if we use technology—and our collective effort—effectively.
Episodes
October 22, 2025 • 27 mins
Can AI help us better understand animals and, if it could, what might we discover? This week’s episode was recorded live at the 2025 Masters of Scale Summit where Reid and Aria sat down with Aza Raskin, co-founder and CEO of the Earth Species Project. Aza and his team are using AI to decode the languages and cultures of non-human species. From dolphins that invent new tricks together to crows that raise each other’s young in commun...
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October 15, 2025 • 37 mins
In this week's episode, Reid and Aria unpack why trust is a practical skill, not just a feeling. Reid riffs on the importance of hands-on investor-founder relationships, boardroom decisions that can make or break a company, and investor behaviors that build durable trust. They also discuss what product teams and policymakers must do to earn user confidence in an age of AI. Along the way, Reid shares personal anecdotes regarding his...
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October 7, 2025 • 67 mins
How can AI really help advance medicine? Should patients and care teams be seeking second opinions from LLMs? This week, Reid and Aria sit down with physician-scientist Dr. David Fajgenbaum, who repurposes existing drugs to save lives—including his own. David shares his journey from receiving last rites as a young medical student to co-founding Every Cure, a nonprofit using AI to come up with ways existing drugs can be repurposed t...
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October 1, 2025 • 35 mins
This week, Reid and Aria dive into the debate over new $100,000 fees on H-1B visas, and discuss how immigration powers U.S. innovation and how to ensure startups aren’t shut out. They also cover developers’ mixed feelings about using AI in coding, the leap from 60% to 85% accuracy in medical AI predictions, and what it will take to bring regulators and clinicians on board. Plus, Reid shares why he’s skeptical of a three-day work we...
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September 24, 2025 • 43 mins
What’s the role of semiconductors—and the companies that make them—in powering human progress? What does it look like to innovate thoughtfully in a landscape where the demand for power may be higher than the supply? With AI evolving faster and faster, how can we keep up?
Advanced Micro Devices (AMD) CEO Lisa Su joins the show to talk about hardware, global manufacturing, and risk-taking. She shares what she has learned leading ...
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September 17, 2025 • 20 mins
This week, Reid and Aria discuss Apple’s new AirPods Pro 3 and live translation capabilities, AI-generated movies (specifically Critterz from OpenAI), and what really could be lost — or gained — as AI technology becomes more widespread. Plus, Reid reflects on his speech at the Bologna Business School two years ago, and how far AI has come since then in amplifying creativity and humanity.
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Superagency
Bro-Botz...
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September 10, 2025 • 56 mins
What could we gain—and what might we lose—when technology begins to approximate the contours of human connection and presence? In this episode, Reid and Aria chat with comedian, actor, and political commentator Stephen Colbert. Best known for hosting The Colbert Report and The Late Show, Stephen combines a razor sharp satire with a sincere curiosity about the world. Together, Reid, Aria, and Stephen discuss the art of live performa...
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September 3, 2025 • 23 mins
This week, Reid and Aria discuss the challenges around integrating AI into organizations and workspaces, China’s recent pivot away from NVIDIA, and OpenAI’s new $50 million NGO-focused fund. Reid also offers his take on a recent Stanford study that looks at entry-level jobs at risk of AI replacement.
For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/
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August 27, 2025 • 55 mins
Gains in the quality of America’s K-12 education in the late 20th and early 21st century have largely plateaued—and , in several instances, reversed—in the last few decades. This week, Alpha School co-founder MacKenzie Price joins the show to discuss her fast-expanding network of AI-powered private schools, which she says represent the reform the system so badly needs. She explains why Alpha students learn core academics in two hou...
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August 20, 2025 • 18 mins
This week, Reid and Aria discuss the much-anticipated launch of GPT-5, Figma's blockbuster IPO, Perplexity’s bid to acquire Google Chrome, and the end of AOL’s dial-up internet service. Plus, Reid offers his take on why some companies find explosive growth and others fade just as fast.
For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/
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For the Hamilton...
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August 13, 2025 • 52 mins
How can we take digitally-empowered democracy straight out of science fiction into reality?
This week, Reid and Aria are joined by two digital democracy pioneers, Audrey Tang and Divya Siddarth. Audrey Tang is a cyber ambassador-at-large and former inaugural Minister of Digital Affairs for Taiwan. Their pioneering initiatives like the Sunflower Movement, g0v, and vTaiwan have fought misinformation and influenced policy decisions...
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August 6, 2025 • 16 mins
Could the very technology that requires massive amounts of energy to power it also be key to solving the climate crisis? This week, Reid and Aria discuss the global energy arms race and why the U.S. is lagging behind competitors like China. Reid weighs in on the environmental impact and human costs of AI infrastructure, along with mounting tensions between hyperscalers and the communities that host their data centers.
For more ...
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July 30, 2025 • 51 mins
What can public libraries teach us about finding and sharing trustworthy information in the age of AI? How can—and should—AI build upon the technology that is books? This week, Reid and Aria head to the New York Public Library in Manhattan for a conversation with the storied institution’s president and CEO, Tony Marx. They explore the function of libraries in the age of AI, debate the future of work, and discuss what it looks like ...
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July 23, 2025 • 24 mins
On Part II of last week’s Live Riff, co-hosted with Village Global, Reid fields audience member questions about scale product-market fit, license modeling, data sensitivities, and the future of customer service, along with positive use cases for deepfake technology and the making of Reid AI, his digital twin. He also tells a story from his PayPal days, when Peter Thiel gave him five days to come up with a solution to a problem that...
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July 16, 2025 • 40 mins
What’s the deal with hyperscalers’ recent string of acquisitions betting big on AI talent? When will business schools start requiring classes on managing agents? And how is—and isn’t—AI changing the path to scale and the future of work? Aria asks Reid about all of this and more in a special two-part Riff, recorded for a live audience of AI leaders and founders in New York City in partnership with Village Global in June.
Specia...
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July 9, 2025 • 28 mins
Crypto often feels like a microcosm of the broader government–tech relationship. On one extreme, you have true believers who see blockchain as the next frontier of economic empowerment and radical transparency. On the other, skeptics who point to ransomware attacks, illicit finance, and the flipside of anonymity—and call for an outright ban.
This week on Possible, Reid and Aria talk crypto –– both the positives and negatives –– ...
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July 2, 2025 • 64 mins
What if AI helped people develop and deepen their existing expertise, and better outfitted them for the jobs of the future? This week, Reid and Aria are joined by one of the world’s leading labor economists, David Autor, Ford Professor of Economics at MIT and co-director of its Work of the Future Task Force. He is also a Visiting Fellow in the Google Technology and Society Program. David’s landmark research on the China Shock has b...
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June 25, 2025 • 25 mins
Aria and Reid dive into the recent flurry of multibillion-dollar AI acquisitions—from OpenAI’s $3B Windsurf deal to Meta’s ~$15B stake in Scale AI—and what they reveal about how companies are racing to refactor for an AI-first future. Are acquihires overtaking acquisitions as the new strategic advantage? And how are companies balancing workforce shifts with long-term innovation? Plus, a look at the robotics boom, government investm...
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June 18, 2025 • 52 mins
What happens when we take numbers seriously—not just at face value, but in terms of their actual impact on our lives?
This week, Reid and Aria are joined by UK-based mathematician and media personality Hannah Fry to explore this deceptively simple question. From cancer diagnoses to dating apps, Hannah makes the case that understanding the math behind our decisions—and the "game" we're really playing—is essential to building a be...
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June 15, 2025 • 19 mins
This episode has been re-uploaded to correct an error. If you are a subscriber and/or downloaded it on its release, consider deleting and redownloading it to hear the corrected audio. We apologize for the inconvenience.
On this week's Riffs, Reid and Aria unpack last week’s conversation with Yuval Noah Harari, discussing AI's rapid advancements, its potential impacts on humanity, and the meaning of consciousness. Reid and Aria a...
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