Possible

Possible

What if, in the future, everything breaks humanity's way? Possible is an award-winning, weekly podcast that sketches out the brightest version of the future—and what it will take to get there. Hosts Reid Hoffman and Aria Finger explore what’s possible with forward-thinking leaders, deep thinkers, and ambitious builders across many fields, such as technology, art, education and healthcare. These conversations center on the ways technology—and, in particular, AI—is shaping the future. In episodes, AI tools such as OpenAI’s GPT-4 and Inflection’s Pi are at work, offering informational asides, prompting guests, or demoing what they can do. Lastly, between guest episodes, Aria interviews her co-host Reid on his latest takes on what’s possible if we use technology—and our collective effort—effectively.

Episodes

Making sense of the layoff wave

February 11, 2026 • 30 mins
In this episode, Reid and Aria unpack the growing panic around layoffs, the actual impact of AI on work, and why autonomous agents are reshaping productivity faster than most people realize. Reid points out that today’s layoffs are being erroneously blamed on AI, rather than on economic turbulence and post-COVID refactoring. The conversation then turns to the viral ClawdBot/Moltbot/OpenClaw moment and explores what it means for pro...
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CryptoPunks creators: from art experiment to cultural movement

February 4, 2026 • 49 mins
Before NFTs were a category and crypto was an industry, two artists released 10,000 characters into the world with no roadmap, no pitch, and no expectations. What started as an art experiment in code ended up flourishing into a movement about ownership and identity. In this episode of Possible, Reid sits down with Matt Hall and John Watkinson, co-founders of Larva Labs and creators of CryptoPunks, to trace how a small creative expe...
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Reid Riffs with Parth Patil on AI-Native Startups (Part 3 of 3)

January 28, 2026 • 34 mins
This episode is our third and final installment of a special, three-part Reid Riffs miniseries focused on what it actually means to become AI-native. In this episode, Parth shares how founders can rethink work by breaking problems into modular pieces, orchestrating AI agents in parallel, and collapsing timelines that once required entire teams days of iteration. Using real-world examples like coding agents that tackle week-long eng...
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Reid Riffs with Parth Patil on Enterprise AI Integration (Part 2 of 3)

January 21, 2026 • 40 mins
This episode is our second installment of a special, three-part Reid Riffs miniseries focused on what it actually means to become AI-native. Instead of a news or headline-driven conversation, Reid sits down one-on-one with AI engineer and strategist, Parth Patil, for a deeper exploration of how AI is changing the way people and organizations work. In this second episode, they discuss why most enterprises are still talking about AI ...
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Reid Riffs with Parth Patil on Individual AI Mastery (Part 1 of 3)

January 14, 2026 • 45 mins
This is the first of a special, three-part Reid Riffs miniseries. Instead of a news-and-headline driven conversation, Reid sits down one-on-one with Parth Patil, an AI engineer and strategist, for a deeper exploration of what it actually means to become AI-native. In this first episode of the series, Parth and Reid discuss how individuals can better leverage LLMs, agents, and creative tools daily. They trace the shift from seeing A...
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Amjad Masad on vibe coding, AI agents, and the end of boilerplate

January 7, 2026 • 79 mins
On this episode of Possible, Reid Hoffman and Aria Finger sit down with Amjad Masad, founder and CEO of Replit, to explore how AI is fundamentally changing who gets to build software and what that means for work, creativity, and human agency. Masad traces his journey from growing up in Jordan teaching himself to code and connects it to his love of video games which helped inspire him to build a platform that turns natural language ...
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BONUS: Conversations with Coleman: Big Tech, Politics, and Trust in Institutions

December 31, 2025 • 67 mins
This is a bonus episode from the Conversations of Coleman podcast, featuring Reid Hoffman as the guest. Here are the show notes from that episode: My guest today is entrepreneur and LinkedIn co-founder Reid Hoffman. He’s now facing something most tech business people never imagine: being personally targeted by a sitting president’s Department of Justice. Reid and I talk through the rise of politically motivated prosecutions, the e...
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Stephen Colbert on connection, discovery, and human nature

December 24, 2025 • 58 mins
This is a holiday special re-airing of our excellent episode with Stephen Colbert. What could we gain—and what might we lose—when technology begins to approximate the contours of human connection and presence? In this episode, Reid and Aria chat with comedian, actor, and political commentator Stephen Colbert. Best known for hosting The Colbert Report and The Late Show, Stephen combines a razor sharp satire with a sincere curiosit...
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The power of AI, from curing cancer to ballot boxes

December 17, 2025 • 31 mins
In this special episode of Reid Riffs, Reid and Aria are joined by Pulitzer Prize–winning author, oncologist, and Manas AI cofounder Siddhartha Mukherjee for a few questions about cancer, AI, and the second edition of The Emperor of All Maladies. Reflecting back on the 15 years since its initial publication, Reid, Aria and Sid discuss how cancer prevention, early detection, and immunotherapy have fundamentally shifted while the dis...
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The AI energy war is here

December 10, 2025 • 18 mins
In this episode of Reid Riffs, Reid and Aria explain why "compute" is the new oil powering the cognitive industrial revolution. They argue that the United States must urgently expand domestic data centers and energy infrastructure to remain globally competitive. The conversation explores how rapid data center construction is transforming blue-collar labor markets, driving significant wage growth for electricians, HVAC technicians, ...
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R.I.P. Computer Keyboard (1964 – 2025)

December 3, 2025 • 44 mins
In this special live episode of Possible, Reid and Aria sit down with Wispr Flow founder and CEO Tanay Kothari to explore a post-keyboard future where voice becomes the primary way humans interact with computers. From building one of the world’s first voice assistants as a child to creating a product now used the world over (with, as of publish, 70% user retention after one year and daily users at over half of the Fortune 500), Tan...
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AI’s Influence On The Church, Cybersecurity, and Disney

November 26, 2025 • 16 mins
This week, Reid and Aria dive into three central AI stories that have been dominating the headlines: Pope Leo XIV issues a powerful call for moral discernment in an AI-driven world, Anthropic reveals that state-sponsored hackers used agentic AI to automate a sophisticated cyberattack, and Disney considers a radical shift as it weighs opening its IP vault to fan creators. Reid reflects on what it means when spiritual, civic, and tec...
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Our AI blindspot: incentives over intentions

November 19, 2025 • 67 mins
Software is eating the world, but will it start eating us? On this episode of Possible, Aria Finger and Reid Hoffman sit down for an encore conversation with Aza Raskin that dives deep into how AI and engagement-driven tech are reshaping our lives, our democracies, and our sense of truth. From unpacking the present challenge around social media feeds to AI systems competing for our time, intimacy, and attention, no technology topic...
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How we regulate AI could decide the next century

November 12, 2025 • 35 mins
In this episode of Possible, Reid Hoffman and Aria Finger explore how AI is colliding with real-world regulation, responsibility, and even civility. As states like Utah, California, and Illinois roll out new AI laws governing everything from chatbot disclosure to bans on AI-driven therapy, Reid breaks down the logic that’s driving these policies. The conversation dives into OpenAI’s self-imposed limits on medical, legal, and financ...
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Reid riffs on NVIDIA's chips, China’s AI ambitions, and the push to pause AI

November 5, 2025 • 30 mins
This week Reid and Aria break down the global AI race from Nvidia’s $5 trillion valuation and the U.S.–China chip rivalry to what happens when AI starts reshaping industries like medicine. Reid explains why the future of innovation depends on how we deploy AI, not just how we build it, and why doctors, scientists, and creators will need to redefine their expertise in a world of intelligent tools. Later in the episode, Reid responds...
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Steve Kerr and Kris Brown on Leadership, Purpose, and Innovation in Sport and Society

October 29, 2025 • 62 mins
What does it take to turn tragedy into advocacy, and advocacy into lasting change? This week, Reid and Aria are talking to Warriors head coach Steve Kerr and Kris Brown, president of Brady, the nation’s oldest gun violence prevention organization. Together, they explore how sports, storytelling, and civic engagement can move the needle on one of America’s most polarizing issues: guns. In the first part of this episode, Steve and...
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Aza Raskin on interspecies communication, empathy, and AI’s next frontier

October 22, 2025 • 27 mins
Can AI help us better understand animals and, if it could, what might we discover? This week’s episode was recorded live at the 2025 Masters of Scale Summit where Reid and Aria sat down with Aza Raskin, co-founder and CEO of the Earth Species Project. Aza and his team are using AI to decode the languages and cultures of non-human species. From dolphins that invent new tricks together to crows that raise each other’s young in commun...
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Reid riffs on fostering trust with founders, in boardrooms, and in AI

October 15, 2025 • 37 mins
In this week's episode, Reid and Aria unpack why trust is a practical skill, not just a feeling. Reid riffs on the importance of hands-on investor-founder relationships, boardroom decisions that can make or break a company, and investor behaviors that build durable trust. They also discuss what product teams and policymakers must do to earn user confidence in an age of AI. Along the way, Reid shares personal anecdotes regarding his...
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David Fajgenbaum on drug repurposing, AI, and saving his own life

October 7, 2025 • 67 mins
How can AI really help advance medicine? Should patients and care teams be seeking second opinions from LLMs? This week, Reid and Aria sit down with physician-scientist Dr. David Fajgenbaum, who repurposes existing drugs to save lives—including his own. David shares his journey from receiving last rites as a young medical student to co-founding Every Cure, a nonprofit using AI to come up with ways existing drugs can be repurposed t...
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Reid riffs on Trump’s $100K visa fee, 3-day work weeks, and AI trust issues

October 1, 2025 • 35 mins
This week, Reid and Aria dive into the debate over new $100,000 fees on H-1B visas, and discuss how immigration powers U.S. innovation and how to ensure startups aren’t shut out. They also cover developers’ mixed feelings about using AI in coding, the leap from 60% to 85% accuracy in medical AI predictions, and what it will take to bring regulators and clinicians on board. Plus, Reid shares why he’s skeptical of a three-day work we...
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