Episode Transcript
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Speaker 1 (00:03):
Hello, this is
Pushing Boundaries, a podcast
about pioneering research,breakthrough discoveries and
unconventional ideas.
I'm your host, dr Thomas RVerney.
My guest today is Faraz Khan,ma Management Consultant and
Longevity Expert.
Welcome, faraz.
Speaker 2 (00:24):
Thank you so much for
having me on Dr Verney.
Speaker 1 (00:26):
It's a pleasure.
So I understand that you haveestablished what you call a
one-stop shop for the besttechniques and latest info and
anti-aging and longevity.
Can you tell me a little bitmore about how that came about
and what it's all about?
Speaker 2 (00:45):
Absolutely so.
I have my background incomputer science.
I was a tech engineer for awhile and then I got into
management consulting because Ifound just writing tech to be a
little bit boring.
I got into managementconsulting, worked with a lot of
firms, especially AmgenBiopharma, which is based out of
in California, 1,000 Oaks, andso I spent some time with them
(01:06):
when I got to learn some of theinsights of the healthcare
industry, and they were makingthese biologic drugs.
We were helping them roll themout, and this would take a lot
of time, a lot of money by somevery well-meaning individuals,
and then the sales team wouldtake over and then they'd go
sell to the doctors and whatnot.
And so that really, when I wasin management consulting in Los
(01:27):
Angeles, I started thinkingabout how could I use some of
these techniques orpharmaceuticals to help my
parents slow down their aging,because I have an Indian
background and family is very,very important and we get guilt
stripped when we spend too muchtime away from our parents, and
so, as part of that guilt andshame, I said what can I do
(01:47):
really to help slow down theiraging?
And so I started Googling andresearching and the rabbit hole
even in 2018, went very deep,and so I started going down the
rabbit hole and learning ofdifferent ways that scientists
are trying Longevity researchersare researching to slow down
and reverse the aging processand I said, wow, there's
something.
(02:07):
So I decided in 2019 to switchcareers actually and quit my
management consulting firmwell-paying job and got into the
field of longevity andanti-aging as somebody who
started a podcast.
So that was my first entry andforay into the field.
I started a podcast where Istarted interviewing a lot of
(02:28):
experts experts in longevity,health, wellness and experts
like yourself, dr Bernie.
You've been on my show to talkabout what are the practical
things that people can do todayto slow down their aging and
what's coming in just five, 10years that can really turn this
field around and allow us tolive in much younger bodies.
So that was how this came about.
(02:49):
We've also got a hair wellnesscompany that we do.
Now.
We sell hair wellness productsfor women to help keep the hair,
because hair is very importantas part of the anti-aging
protocol.
Speaker 1 (03:02):
Right.
So you mentioned your parents,that you were sort of concerned
about their aging.
You also mentioned the factthat they kind of have a way of
guilt-tripping.
So have you found a remedy forguilt-tripping?
Speaker 2 (03:20):
I think I need to
consult with you on that.
Good answer.
Speaker 1 (03:23):
Very good answer.
Speaker 2 (03:25):
That is a challenging
topic for sure.
I think I'm becoming more awareof their guilt-tripping, but
they're just set in their ways,and my mother especially.
They use whatever ways theyhave to get their children to
comply.
Speaker 1 (03:38):
Really, so on your
website and I think you pretty
well said it also here in thelast few minutes you have said
that there are very promisingdevelopments unfolding over the
next five to 10 years that maymake diseases like heart disease
, cancer, alzheimer's anddiabetes a thing of the past
(04:02):
will be living like how muchyounger cells full of radians,
vigor and energy.
So what are these newdevelopments that you're talking
about?
Speaker 2 (04:13):
Totally.
Let me fill your audience in onwhat's going on in the field of
longevity the most excitingstuff.
So what's happening is that alot of Silicon Valley
billionaires and people thathave made a lot of money in
technology are realizing thatthey're mortal after all and
they'd like to change that, andso they're investing a lot of
their money.
Jeff Bezos is one of theinvestors.
(04:34):
Google co-founder Sergey Brinis another investor.
We've both started funds andcompanies and there's many more
that have been started that areresearching different ways to
slow down the aging process.
Now we've known for many yearsthat there were about nine
hallmarks of aging that werefounded or discovered or agreed
(04:54):
to by scientists in about 2014.
Recently, that list hasexpanded from 14 to 19.
Sorry, there were nineinitially and now five have been
added, so now there's 14 intotal.
So all of these they talk abouteither stem cell exhaustion or
epigenetic information, so inyour cells the epigenome is not
(05:14):
working properly because of theenvironment.
There's now an inflammation,has been added, there's telomere
shortening, so there's about 14different hallmarks that they
call of aging.
So a lot of these companiesthey're going after, they're
getting funding, they're hiringa bunch of really smart
scientists and they're goingafter individual hallmarks.
So some are saying we're goingto go work on stem cells, some
(05:37):
are saying we're going to workon cellular reprogramming, some
are saying we're going to workon cellular senescence, and I'll
explain all of those in asecond.
So there's funding coming in.
Because of funding they canhire very, very good scientists,
and these funding and thescientists together are allowing
them to do studies on smalleranimals like mice, rats, fruit
(05:57):
flies, for example, that areshowing very, very promising
results in terms of increasingthe longevity of these animals.
And what's interesting is,because mice only live about two
years or so, you can measurethe increase in longevity very
easily, because if they live tothree years, that's a 50%
increase.
If they live two extra months,that's about whatever, that is
(06:18):
12% or so.
So it's easy to measure that.
And now, because they're socommon with the genome, with
mice and rats and us, thatscientists are now figuring out
ways to kind of use human trialsto show the same outcomes.
And so that's what's reallyhappening, and I can dive into
the two hottest areas.
(06:38):
Out of the 14 hallmarks paging,there's two that are super hot
right now.
The number one area, dr Bernie,is called cellular reprogramming
so in I believe it was 2012when a Japanese scientist
discovered these fourtranscription factors, which are
basically proteins that turn onspecific genes inside your
(07:01):
cells.
So these four proteins wereturning on specific sets of
genes that were transferring ahuman adult cell into an
embryonic cell, so going all theway back to a stem cell, which
means then it can become anycell from that point on.
So then it can divideindefinitely.
This was a shocking developmentthat they found that any adult
(07:25):
cell that has been alive for 50,60, 70 years, that cell could
be taken back to an embryonicstate and then it can divide
indefinitely.
So that led to concern thatwell, this might become
cancerous, because if a cell candivide indefinitely, that's
what cancer does it just divides.
And so they started testingwith those different
(07:45):
transcription factors.
Now the current, I guess,consensus is that there's three
out of those four that you canuse and that will not cause
cancer.
And so there's one researchstudy that was published just a
week ago by a team at HarvardMedical School, by Dr David
Sinclair, which showed that theycan use these three different
(08:06):
transcription factors to reverse, increase and decrease
somebody's epigenetic age or notsomebody's, but cells
epigenetic age.
Very, very.
I guess you could redo it overand over again.
So it's something that can berepeatable and it's shown in
these studies.
There's also multiple otherstudies that were done in the
(08:27):
last year that had the same orsimilar results with these three
different factors.
So again, very promising area.
A lot of money I think the mostmoney in anti-aging is probably
going to this one area.
The second area that's also very, very interesting is called
cellular senescence.
So I just want to explain thatreal quick.
What happens is human cellshave a limit.
(08:50):
They divide about 50 times.
It's called the Haiflich limit,and the reason scientists
believe that they divide only 50times is because the DNA, when
a cell divides the end caps ofthe DNA, it's this protective
chromosome at the end.
That is not really DNA, but it'sjust a chromosome that's
protecting the DNA.
So it's like the end caps ofyour shoelaces that are
(09:13):
protecting the shoelace, and sowhen a cell divides, the end
caps or the chromosome at theend shortens every single time.
We just called the telomere,exactly, you got it.
Yes, and scientists believethat after 50 divisions the
telomeres become so small thatif you divide the cell anymore
then it may cause mutations inthe DNA, which could lead to
(09:36):
cancer, and so that's why a cellis very smart it stops dividing
.
Now there's ways to allow, andso once the cell stops dividing,
then it turns into what theysay old, grumpy man.
It's called the senescent cell.
That's just angry and just madat the world, and it's secreting
these inflammatory phenotypesand inflammatory substances in
(10:00):
the cell.
So it's like poisoning thecells around it.
So scientists are looking atways to turn these senescent
cells old grumpy men, into youngcells again and reducing that
burden, that load that we'recarrying because of this and
inflammatory excretions thatthey're doing.
Speaker 1 (10:20):
As far as they have
been, no ill effects of this.
Speaker 2 (10:26):
One of the companies
called Unity Biotechnology that
was funded by Jeff Bezos,founder of Amazon, actually did
a big trial last year and it hada failure.
It failed.
They tried it in the knee.
Some people think that becausethey were injecting the material
, that's why it didn't work.
(10:46):
They should have given itorally because it's a whole body
problem.
Regardless, the trial failedfor the senolytic cells
senescent cells.
That same company is doingadditional trials this year and
there are many other companiesthat are doing trials in
senescent cells as well.
That is the second most fundedarea.
Scientists believe that sooneror later we will find a way to
(11:09):
figure this out or to reversethe age and get rid of these
senescent cells.
The third very interesting areaof recent interest is a theory
that was expounded first byDavid Sinclair, who's at the
Harvard Medical School.
He's got a lab there.
He talks about that all ofaging comes from a loss of
(11:29):
information in the cell.
The cell loses informationbecause the epigenetics of the
cell, the methylation patterns,because of the environment,
cause it to forget that it's ayounger cell.
It stops creating the proteinsthat keep you young.
As we age, it creates differentsets of proteins and those
proteins correlate to the agethat you are.
(11:50):
For example, gray hair, hairloss, diabetes and other
diseases that are associatedwith age are because of the
information theory, meaning thecell has forgotten the original
age that it came from and how itshould function with the
proteins.
What they're doing is, again,they're using that type of
(12:12):
manipulation with the threefactors to get the cells back to
a younger state as well.
That is Dr Sinclair's team.
They just launched a recentpaper that had some success in
that field.
Speaker 1 (12:28):
You said that cells
divide approximately or always,
only 50 times.
Speaker 2 (12:36):
Generally, always
generally 50 times.
That was known for the longesttime as a hard limit for the
cells.
As scientists are able toincrease the telomere length,
especially in petri dishes andlabs, then they can see cells
dividing more Inside the humanbody or in natural circumstances
.
They believe 50 is the limit,but of course that can be
(12:57):
manipulated.
Speaker 1 (12:59):
In terms of 50, how
many weeks or months or years
pass between cell divisions?
Is 50 cell divisions the sameas 50 years, or is it 100?
What is it?
Speaker 2 (13:14):
That's a great
question.
It really depends on the partof the body or the organ.
For example, the cells in yourgut are dividing every five days
very rapidly.
The cells in your brain hardlyat all.
Speaker 1 (13:27):
Right.
Speaker 2 (13:28):
In some brain cells,
a child, or when you become an
adult, pretty much 90 to 95% ofthose cells in your brain stay
constant.
There is some rejuvenationgoing on and some division going
on in the brain, but it's very,very small.
That is the problem we comeinto, especially with longevity.
One of the toughest problems tosolve is the problem of
Alzheimer's.
Is what do you do when thebrain stops supporting you and
(13:51):
you lose mental function?
Speaker 1 (13:55):
Do you rely on the
body to make up for it?
Speaker 2 (13:59):
Interestingly, there
has been two people that are
researching Alzheimer's havebeen very positive in the last
few years.
There were two trials this yearalone, just in the last two
months, that were very promisingto slow down the progression of
Alzheimer's by the slowing downbeta amyloids is what happens
(14:20):
in the brain.
Two big pharmaceuticalcompanies have had positive
trials of reducing or slowingdown Alzheimer's.
Experts that I talked to inthis field believe that
Alzheimer's will become just achronic condition that we can
manage, For example, like we dowith diabetes or other chronic
conditions that stay with us butthey don't kill us.
We don't forget everybody.
(14:43):
We know we don't die because ofit.
It's more going to be somethingwe maintain.
We measure tests to see howwe're doing.
They believe that combinationof pharmaceuticals and or
lifestyle changes can actuallyhave a positive impact when it
comes to Alzheimer's disease.
Speaker 1 (15:01):
Coming back.
I'm fascinated by this number,50.
Is it the same in all mammals?
Is it different in mice thanhumans?
How does it work?
Speaker 2 (15:15):
At this point in all
the mammals that have been
tested.
That is the limit.
It's called the Hayflick limit.
It goes about 50 times becauseall the most of the DNA between
us and mice.
It's mainly almost identical,with some variations.
They do function the same wayacross most of the organisms
that have been studied.
(15:35):
That seems to be thetheoretical maximum limit.
Speaker 1 (15:39):
As you said, mice
only live about two years.
The average age expectancy forhumans, let's say North America,
is over 70, with somedifference between men and women
.
Women living longer Is it?
In mice the 50 cell divisionshappen much faster than they
(16:03):
happen in humans, right Correct?
Speaker 2 (16:05):
Now it's also
interesting to note that humans
have a lot more cells which aredividing 50 times.
So that's number one.
Two we also have a lot morestem cells, and stem cells is
what allows new cells to come in.
So let's say that if we didn'thave stem cells, we would
probably run out of divisions in10 years or so.
(16:25):
But every organ, every tissuehas a bank of stem cells.
So when the normal cells aredividing, the stem cells monitor
the situation and say, okay, weneed more base cells.
And so a stem cell what'smagical about it is it comes out
and says, okay, we need morecells.
It divides into two.
One is a daughter stem cell,which goes back and goes back to
(16:46):
the niche and just rests.
And the other cell now is abrand new cell that has 50
divisions left to go right.
So that's how stem cells keeprecreating the base level of
cells that we have, so they canstart the division process all
over again.
Speaker 1 (17:01):
So then you would
agree with me that cells are
pretty intelligent.
Speaker 2 (17:04):
They're very
intelligent.
That is your thesis of having amemory and a conscience.
The more we learn about thebody, the more we know it's not
just in the science.
There's more going on.
Right now.
It seems metaphysical, it seemsout of the world, but I think
science will get closer andcloser to exactly what you're
saying and we'll know that asproof soon.
Speaker 1 (17:28):
So just changing the
subject a little, about changing
our focus just a little bit.
What can the longest livedpeople teach us about health and
longevity?
Has that been looked into?
Speaker 2 (17:40):
Totally.
These zones where people liveroutinely live over a hundred
years.
There are centenarians, someare called super centenarians
because they live over a hundredand ten years, which is
fantastic, and so there's aboutfive zones in the world and
they're called the blue zones,and scientists have been
studying these blue zones for along time.
We can learn quite a fewlessons from them, in that these
(18:03):
people are.
What they do is all of themseem to have a purpose in life,
and the reason they wake up isthey have something to do.
For example, I went visited ablue zone in Okinawa, japan, and
I met with a 97 year old womanand a 92 year old man, and they
(18:24):
had their daughter was actuallytranslating, their daughter and
their son.
His son were translating and Iasked him a question of why do
you wake up in the morning,every morning, why are you
waking up?
And the woman flat out said Iwant to live, to be a hundred
years old, because the wholetown of the whole town of
longevity, the village, reallyis going to celebrate me.
(18:45):
Wow, what a concept.
The whole town celebrates them.
They have a parade andeverybody comes together, so
they have a reason to wake up.
In fact, her daughter told methat when she woke up in the
morning, she put makeup on everymorning and I said, why, in
case somebody comes to visit her?
And I said, does anybody cometo visit?
She goes very rarely, but sheputs it on anyway.
(19:06):
It makes her feel good.
So these people and the bluezones, they have a reason to
wake up in the morning.
They have a reason to live.
They've got very strong socialconnections.
So they, a lot of them, live inmulti-generation households.
So the kids, grandkids, andparents and grandparents are
typically living in the samehouse, so they're taking care of
(19:26):
each other.
It's not like, oh, the parentshave to go to hospice and the
kids are in daycare all day.
It's all a very combined familyunit that takes care and
watches out for each other.
So that's another thing thatthey do.
That's really really well.
Also, this connection they haveconnections and friends across
and they have very long, verylong friendships right, you know
(19:48):
this.
That helps them go through thetough times in life, which I
think you can speak to as well,very well there.
So that's something that'simportant to them.
They also have a higher purposein life to have a faith, a God
they believe in, and so thatseems to carry them along as
well.
In addition, they move all thetime.
So what we have in the currentworld, dr Verney, is we have a
(20:11):
lot of mental stress and we havelow physical stress, meaning
we're not moving the body asmuch as we should.
They have the opposite problem.
They have a lot of physicalmovement.
They're building fences,they're milking cows, they're
walking their sheep up the hill,up the mountain, and they have
low mental stress.
They're surrounded by family.
(20:33):
There's no technology, no cellphones.
That's a simple life, and sothat's what they have.
That's going on for them.
So, again, I can go on and on,but those are some of the key
factors how these longest livedcivilizations are continuing to
live a very long life.
Speaker 1 (20:49):
Well, I can certainly
identify with that.
My mother lived 202.
Beautiful, and she always puton makeup before she went out.
She put on sunglasses so thatpeople wouldn't see my wrinkles,
she said, and she was verysocial, which would drive my
(21:11):
father crazy because she wouldbe on the telephone for an hour
with one of her friends and,according to my father, she
would talk about nothing, butwhat she was doing, of course,
was connecting right.
And so you know it was I'm sureit was.
It was motivating her andhelping her to live to a very
(21:35):
good old age, 102.
And she was perfectly fine inher head, like not a touch of
Alzheimer's.
Speaker 2 (21:43):
Which means you have
great longevity genes in your
family.
Speaker 1 (21:47):
Yes, so far so good.
Yes, and I'm the same way,though without the makeup, but I
certainly, you know, have apurpose and I have lots of
friends and lots of socialcontacts.
So, yeah, I certainly subscribeto that.
(22:07):
Now, in terms of your own life,was there anything in your own
background that you thinkcontributed to your interest in
this subject?
I mean, first you went intomanagement, I know, but
underneath it perhaps there wassomething else.
Speaker 2 (22:23):
Yes, so I think the
biggest.
There are two reasons for it,primarily or three, I should say
I wasn't completely satisfiedwith the life choice that I had,
with management, consulting andworking for a big corporation
and a big city.
I just felt like there wassomething missing.
I had.
I didn't have purpose in mylife, waking up and serving the
organization and making themmoney and making myself money
(22:46):
and living a good life, while itseems really good for most of
the world to think about, but itwasn't all that fulfilling for
me.
That's number one.
Number two I wanted to be in atechnology which would be in the
future, something that wascoming, that was new and
exciting, and so I literallylooked at seven or eight
technologies that I could getbehind.
Artificial intelligence was oneof them, augmented reality,
(23:08):
virtual reality sensors, 3dprinting, robotics and longevity
.
And then I said which of thesefields can I make the smallest?
I would have a difference.
What can I do something in andwhat am I interested in?
So I think that longevityappealed to me because not only
could I help my parents whichwould be something I would give
(23:30):
back to them, right but also Iwant to look and feel young when
I'm older and I want to live ayounger and much longer life,
and so part of it was personal,part of it was for my parents,
part of it was finding somethingthat excited me, that was a
little bit out in the future,and then part was just
dissatisfaction with my currentstate.
Speaker 1 (23:50):
Are you presently in
an intimate relationship?
Speaker 2 (23:54):
I am not currently,
because I'm focusing all of my
time and effort into building acompany and making money.
That is something that Irealize that I'm lacking at the
moment.
Speaker 1 (24:07):
Yeah, Well remember,
social relationships are
important.
Speaker 2 (24:12):
Yeah, so absolutely,
I agree with you 100%.
What I am doing in fact is I'mbuilding in the moment while I'm
not dating actively I'mbuilding a set of friendships.
In Austin.
I'm in a part of men's actuallytwo men's groups where we get
together every two weeks and weshare we really share deeply
(24:33):
about our lives, all the thingsthat are going wrong.
There is no facade in thisgroup.
There is no personas that webring.
We just lay it all out and sayhere's what's going wrong.
Well, here's what I had somechallenges with, and that really
helps get to the core, becausemen, we don't really like to
talk about emotions, and so withboth of these groups, I think
that what I love about it is weare so humble and honest with
(24:56):
each other and so open abouteverything that we get a lot of
feedback from men, but alsosupport if we need to one-on-one
Okay.
Speaker 1 (25:05):
So how important is
mindset for a healthy and long
life?
Speaker 2 (25:12):
It's probably the
most important.
So let me just run yourlisteners through a simple
exercise.
So just play along with me ifyou're listening.
So let's say I'm going to askyou how long, or how long do you
want to live?
What is the age that you thinkit will be your time to pass on?
Let's just think about that fora second.
You don't have to write thisnumber down, but just think
(25:33):
about that.
Now.
If I ask you one year beforethat you reached that age, how
would you feel physically?
Would you be full of life, orwould you be barely moving at
all?
How would you feel mentally?
Would you be sharp, would youhave mental equity, or would you
be not recognizing peoplearound you?
So I think for most people, theanswer would be I'd be mentally
(25:57):
sharp and I'd be physicallystrong.
If that is the case one yearbefore it's your time to go, do
you really think you would gothen?
Because you're in a good place,right?
So then what's the real age?
But people that do this exercisewill add another 10 years to
their perceived time longevity,life, right, life that they
(26:20):
think they'll live, which isfascinating, because now in your
mind, you have to plan forbeing 95 if you said 85 earlier,
and so that unlocks a shift inyou where you say, no, I have to
build a better body, I have tobuild a better mind, I have to
take care of myself, I have tohave friendships, relationships,
and you just plan for 10 moreyears.
Right, and it all starts withthe mind.
(26:42):
We also know that.
You know this, dr Varney.
This is what you do.
You talk to people and youfocus on the mind.
You're an expert on the mind,and even with all the studies,
all the learnings, we have themindset, the purpose.
It's more important thananything else that you can do,
because if you don't have apurpose for example, people that
(27:04):
quit corporate America rightOne year after retirement your
chances of death increased by11%.
It's a shocking number, becauseyou've lost your purpose to
wake up in the morning, and sothat's why a lot of people, a
lot of experts in the longevityworld, say that if you want to
live a long life afterretirement, that is not the end
(27:26):
of your career.
You have to start.
You should start.
You should consider starting asecond career.
Maybe you can coach youngerindividuals that are coming up
behind you, maybe you can starta garden, maybe you can start
gardening, or maybe you can dosomething else.
Save the planet, save theoceans, where you feel compelled
to wake up in the morning,because that is what is probably
(27:48):
the most important thing forlongevity.
Speaker 1 (27:51):
Beautiful, very good,
very good.
So I noticed on your websitethat you say that you only
recommend things supplements.
I guess that you use yourself.
Is that true that?
Speaker 2 (28:06):
is true, correct, yes
, now I use a lot of supplements
, but there are some that I lovemore than others, and I like to
think of longevity as an onion.
You have to peel certain layersto get to the root, and the
opposite is also true is youbuild from the core and you
start and you keep adding on.
(28:26):
A lot of people in this spacewill go get a stem cell
treatment without optimizingtheir sleep or their exercise,
and to them I say, okay, okay,if you have $5,000 or $20,000,
feel free to spend it, but itwill be much better use of your
energy resources and time andmoney if you could start to
optimize some of the core layersand then add on things as they
(28:50):
make sense to the level thatyou're at.
Speaker 1 (28:53):
So what do you
consider the core layers?
Speaker 2 (28:57):
So yeah, absolutely.
The base layer for me isconsists of four items.
Number one getting good sleep.
Number two exercising everysingle day.
People say that if you couldcreate a pill that had the
effects of exercise in it, itwould be the first trillion
dollar company ever made.
So it's that important.
(29:17):
Exercise is that important.
So it doesn't mean you have togo lift for 45 minutes at the
gym every evening.
No, let's look at the longestlift people.
They're just walking all thetime.
They're walking for an hour ortwo a day, sometimes in the
sunshine, sometimes in theevenings, but they're just
active all day long.
Right?
So do something.
If you're sitting at a desk allday, then find a or get a
(29:39):
standing desk where you canstand, take a break every hour,
walk for five minutes Simplethings, it's not complicated.
So we talked about sleepexercise.
Nutrition is very important Inthe blue zones.
Most of the people that livethere are eating primarily a
plant-based diet with some meatand some fish.
Experts call this akin to theMediterranean diet, which is, of
(30:01):
course, probably the moststudied diet when it comes to
longevity interventions, and sothat's a good one.
I will not say that there isone diet for anybody, but
Mediterranean, by and large,seems to work for the most
number of people.
So that's number three.
Number four is something you'rean expert in.
Mental resilience is keepingyour mental stress as low as
(30:23):
possible, and this is importantfor a variety of reasons.
When cortisol gets imbalancedin your body, that causes a lot
of problem.
That causes you to be in fightor flight all day long, which
activates certain parts of yournervous system and your body
that don't need to be activatedat all time.
You're not running from a tigerall day, and so these are the
four core components that youshould do first, before you get
(30:45):
into supplements, before you getinto stem cell treatments and
whatever else we can add on tothat.
Speaker 1 (30:51):
Okay, so then that
takes me to the next question.
So what are your favoritesupplements?
Speaker 2 (30:58):
Okay, fantastic.
So these supplements are Let melist them in order Number one
and I'll explain just a littlebit about each of them.
Sure, the first one whathappens to a human body past
middle age is, let's say, whenyou were a child and you were
cycling down the street and youfell down, you bruised your knee
.
Typically, you'll seeinflammation on that wound,
(31:19):
where your body's sending theimmune system to heal, but that
causes some swelling, redness.
That's what's inflammationinside the body, and naturally,
once it's healed, it goes away,right, right, but starting
middle age and beyond, we havehumans build this problem called
inflammaging, which means wehave a chronic, low-grade
inflammation in various parts ofour body, and that's basically
(31:42):
immune system.
Either there's a microbe orpathogen that came in that's not
completely been resolved, or isjust misfiring and attacking
your own cells, and so we wantto calm that down as much as
possible, because it's one ofthe reasons you age faster.
It's called inflammaging.
So we want to reduceinflammation and there is
natural substances, for example,curcumin, which comes from
(32:05):
turmeric, which is an East Asianspice, which is very, very good
for reducing inflammation fromthe top down, all the cascades
that start from the very top.
It's very effective at stoppingthe cascade even before it
begins, so that's something thatI love taking every single day.
I highly recommend it toeverybody else.
Speaker 1 (32:26):
I take it too, I take
it out.
Fantastic, yeah, fantastic.
Speaker 2 (32:29):
Yeah, that's a really
good one.
The second one that I wouldtalk about is something to
reduce the oxidative stress inour body, like an antioxidant.
For example, you walk out inthe sun for too long, that
causes DNA damage and breaks,you inhale polluted air, or you
drink bad water, or you eat thewrong food, or there's chemicals
(32:50):
in your beauty products.
All of these are attacking thehuman organism, the cells, and
your body needs a defense, soantioxidants are quite helpful
for fighting back against theseinsults to our body, and so my
favorite antioxidant is calledastaxanthin, which comes from
Hawaiian not Hawaiian, but algae, blue-green algae and that
(33:12):
astaxanthin is the reason salmonare red, and the reason I
brought up Hawaii is there's acompany from Hawaii that I buy
my astaxanthin from.
They make very good qualityastaxanthin, but so not only is
astaxanthin a very, verypowerful antioxidant, but it
also enables your body to createmore antioxidants in its own
(33:33):
body.
So it helps your body createmore, which is fantastic, and
it's completely natural.
It comes from algae.
Algae, basically, is the foodsource for the entire ocean and
some might say for the entireplanet, but certainly for the
ocean and so it's in the algae,and so that's where we get it
from.
So that's number two.
The third one that I like to dois I want to balance my stress
(33:56):
levels because, as you know,this Dr Verney stresses out of
control these days and it causesyou to go to fight or flight
all day long.
And even your traumas fromchildhood can cause your stress
levels to erupt, and so thetraumas please talk to Dr Verney
about.
But for the actual stressesthat you have in the environment
or in your body, you can usenatural adaptogens.
(34:19):
Ashwagandha is one of theadaptogens that has been used in
Ayurvedic medicine forthousands of years.
You can use.
There's a rodeola that you canuse that comes from Russia.
That's also pretty effectivefor balancing your stress as an
adaptogenic way.
So that's something I recommendfor stress.
(34:41):
Then we get into blood sugar.
This is extremely important.
What happens so I'll explainthis very, very quickly when you
eat a high carb no rush, takeyour time, don't rush, okay.
When you eat a highcarbohydrate meal, what happens
is that that converts into sugarin your body.
So your body converts that intosugar that goes through your
(35:01):
intestine.
The carbohydrates get absorbedback into your bloodstream.
So now there's a lot ofcarbohydrates, or blood sugar
that's now circulating in yourbloodstream.
So your body naturally sendsinsulin to shuttle that into the
cells.
The cells can use that tocreate energy, but beyond a
certain point you just can't fitany more insulin or any more
(35:22):
sugar into the cells.
And so this sugar is nowfloating around on the
bloodstream and it likes toattack things.
It attacks the proteins thatare doing all the job in your
body.
It attacks the DNA in yourcells, it attacks the blood
vessels themselves and it alsoattacks collagen.
Collagen makes up 70% of yourbody, at least of the skin, 70%
(35:44):
of your skin and it makes up themajority of your organs as well
that are internal.
So for all these reasons, it'svery important to reduce the
sugar levels in your bloodstream.
How do you do that?
Well, number one, you could eata low carb diet to begin with,
which Mediterranean diet, forthe most part, is low carb.
It's not high carb, at least.
In addition, what I do is Itake this supplement called the
(36:06):
berberine Burberry again, eastAsian supplement, natural.
It's similar to metformin, butit's natural, and so what it
does is reduces the blood sugarspikes that happen.
It reduces blood sugar,improves the blood sugar
regulation in your body so thatthe blood levels stay stable and
(36:27):
stay nice and low, because thensugar can attack various organs
and collagen in your body.
The other thing I do almostalways people can do, even if
you don't want to take Burberryis after every meal I take a
15-minute walk.
This has been shown inscientific studies to reduce
your blood sugar levelssignificantly.
(36:47):
15-minute walk after every mealyou get the steps in, you get
some exercise and you reduceyour blood sugar levels.
So all you're winning in allways.
So that's number four.
I will have a couple more ifthat's okay.
Speaker 1 (37:01):
Yeah, absolutely.
Speaker 2 (37:02):
Okay, collagen is
extremely important to us.
As I described, 70% of yourskin is collagen.
Most of your organs are made upof collagen and as we age, your
body produces less of it, andso it's vital for us to get more
collagen.
You can get it from two sources.
You can get hydrolyzed collagensupplements that can easily go
(37:23):
through your gut and be absorbedby your body they're a little
bit more expensive or you canjust take gelatin.
Collagen is also something thatyou can drink in a cup of tea.
Unfortunately, you have to mixgelatin with something warm,
like a warm liquid, otherwise itgels.
It's not so easy to kind ofthen eat that Collagen doesn't
(37:45):
have that problem, but you canuse either.
Or they have all the aminoacids that you need for your
body to form the collagen.
You can also take a little bitmore vitamin C, a little bit
more copper and some manganese.
That helps your body create thecollagen internally.
So that is something that Irecommend I take every single
day.
Collagen is very important foryou.
And then a last one that I'llmention here, or last two real
(38:09):
quick is called NMN, and NMN isbasically there's a material or
substance in your body calledNAD.
It's called nicotinamideadenine dinucleotide, and so
what this does?
It has multiple functions.
It helps create energy.
It's available in your cell,but it helps your body create
(38:31):
more energy through themitochondria.
It also helps repair DNA damageand thirdly, it also helps with
supporting these proteins orenzymes called sirtuins.
Sirtuins are called thelongevity genes.
They're in every cell and soNAD is important for supporting
the function of sirtuins normalfunction.
So for all these reasons it'sextremely important.
(38:54):
There's a lot of buzz in theanti-aging world about NAD.
There's two ways to actuallysupplement.
To get enough NAD in your body,you have to take precursors,
because the NAD molecule is justsimply too big to get into your
cell directly.
So the two precursors are NMNis a quite popular one.
The second one is called NR ornicotinamide riboside.
(39:16):
You can take either or theyhave good data behind more of
them.
I took NR for many years.
I've started taking NMNrecently.
It doesn't matter as long asyou take one of them.
So that's important.
And the last one I'll say isfish oil.
It's simple, it'santi-inflammatory and it's also
very good for the EPA and DHAlevels that are all the fats
(39:38):
that are inside your brain.
We want to support your brainand fish oil seems to be
extremely good at doing that.
Speaker 1 (39:43):
So is that like omega
?
Speaker 2 (39:45):
Yes, omega 3.
Speaker 1 (39:47):
Omega 3.
Yeah, what about garlic?
Speaker 2 (39:52):
Garlic is good.
Again, I eat garlic.
I don't supplement with itGarlic and ginger.
They're extremely good, bothfor fighting off fungal
infections, bacterial infections, but also from a longevity
standpoint.
So those I would just recommendmaking it part of your foods
and, if you want to take agarlic supplement, absolutely.
(40:12):
It also helps improve bloodcirculation.
Garlic does, and so that's it'sin certain supplements for that
reason as well.
Speaker 1 (40:24):
So I mean, it really
sounds as if you had acquired a
really deep understanding of thecells and, on a microscopic
level, how they work.
How did you learn about allthis?
Speaker 2 (40:42):
It's passion, right?
So when I said to you I lookedat 708 different fields and
where could I make an impact andwhere was I interested, I'm
genuinely interested in thescience behind it.
I'm generally interested in howcells work.
In fact, when I was in college,my parents wanted me to go to
med school but dissecting a ratturned me off because it smelled
(41:05):
so bad and I didn't want to cutup animals.
So that's the reason I didn'tgo to med school.
But I've always had afascination with biology and how
the body works and how you canchange your inputs to the body
so you can change the outputsand the function.
Just fascinates me a lot.
Speaker 1 (41:22):
Well, I'm really
impressed because I know a
little bit of science andeverything that you say is right
on, and I'm just amazed thatyou didn't go to university to
study all this, but that youjust acquired it on your own.
Speaker 2 (41:39):
Yes, thank you very
much, dr Varney.
I also have the privilege oftalking to anti-aging and
longevity experts every week,such as yourself, as I said, and
that also helps me clear someof my doubts and ask very
intelligent questions so that Ican keep educating myself.
Speaker 1 (41:55):
So, in terms of what
you have just said, now, who can
you think of as the three mostinfluential people in your life?
Who are three people who havemost influenced you?
Speaker 2 (42:09):
Yes, excellent
question.
I think the number one personthat influenced me the most is
Tony Robbins, Because, yes, Iwas like I said.
The changing of my job andstarting a new career where I
knew nothing, it was completelyfresh start Was so
nerve-wracking and for some it'snot, but for me, maybe because
(42:31):
of my old traumas aroundscarcity and lack and not having
enough right.
Yes, I was a huge roadblock andI was struggling to cross it.
I'd been thinking about it fortwo years, but going to a few
Tony Robbins events gave me thejet fuel that I needed to really
take the move.
The number two person that Iwould say that has been a big
(42:52):
influence on me is Dr PeterDiamandis.
He's an entrepreneur, he runsAbundance360 and he invests in a
lot of tech startups.
He's very well known in thetech startup world.
He finds funds, creates fundsto fund really interesting
challenges for space travel or,in other ways, moving the planet
(43:17):
forward, and he's a veryabundant thinker.
He's a futuristic thinker, andso he's somebody I look up to as
an entrepreneur, as usingtechnology, for really moving
the needle and for gettingexponential returns in a shorter
amount of time.
The third person that I look upto is Ray Kurzweil, who is an
ex-Google engineer, very, veryaccomplished entrepreneur.
(43:40):
He's got tons and tons ofinventions that he's created,
and he is the person that coinedthe term longevity escape
velocity.
So, according to him, 86% or 84%of all of his predictions have
come true, by the way, which isastounding because he's almost
80 and he's been saying thingsfor a long time, and so he
(44:03):
believes that in this decade, inthe 2020s, before 2030, we will
achieve longevity escapevelocity.
And what is that?
That for every year that we agechronologically, we will have
the technology available toreverse the age by more than a
year.
So we're, in effect, usingtechnology to reverse aging
faster than we are aging.
(44:24):
So we're starting to go back intime, and that is very
fascinating because in thefuture and I'll just say this in
the future, there will beprobably 3D printed nanobots
that will be monitoring ourbodies.
There will be mirrors with allkinds of iris scans that will be
monitoring how we stand, howwe're looking, perspiration,
(44:48):
heart rate, blood sugar levelswill be monitored real time, and
I think that even beforesomething like a cancer or like
even diabetes can manifest inour bodies, we will know way
ahead of time using real timetechnology.
And so, as humans, we may haveto become open to using more of
(45:09):
technology in and around us, andthat can really help us if used
correctly, in the right way.
Speaker 1 (45:20):
Very interesting.
What is the most importantlesson you have learned about
life as of today, as of thismoment?
What would you say is the mostimportant lesson you have
learned?
Speaker 2 (45:38):
What a beautiful
question, and the lessons that
I've learned has nothing to dowith longevity or living a long
life.
It's more a perspective of that.
There's eight billion people inthe world and everybody has a
unique path through life, andeverybody gets their stressors.
They get their circumstancesthat are placed in their life.
(45:59):
Nobody has it easy, and thebest you can do is to make the
best of the circumstances thathave been given to you.
And what's most important forme is perspective.
What's most important for me iswisdom.
Talking to people like you, drVerney, and now you know, in the
beginning, when I was ateenager, I would think, oh, you
(46:22):
know, I'm so young, I'minvincible, I don't want to talk
to older people.
Now I want to sit down at yourfeet and ask you questions about
.
Give me wisdom, because there'sa lot of things I'm not seeing,
that are, that are just coming,that are right behind the
corner, that I haven't eventhought about yet, and so it's
more a perspective of how can Ibest manage my circumstance and
(46:43):
how can I learn from people thatare ahead of me.
Speaker 1 (46:46):
Wonderful, wonderful.
Well, you're doing a remarkablejob and you're just beginning,
so who knows where you're goingto be in 10 years, right?
Speaker 2 (46:56):
Totally, I'm super
excited and, yeah, thank you for
coming on my show.
It was fantastic and I'd liketo stay in touch with you and
check base and have you back onmy show next year as well.
Speaker 1 (47:07):
Sure, so before we go
, would you please email me the
names of the six supplements sixor seven supplements that you
mentioned as really important,and I will add them to the
podcast so people know andpeople can reach you at fully
vitalcom, correct, yeah?
Speaker 2 (47:29):
So that's for the
hair wellness is fully vital.
Speaker 1 (47:32):
Oh, that's just for
the hair and the rest of the
supplements.
Speaker 2 (47:35):
Yeah, so the rest of
the stuff is on
antiaginghacksnet.
That's where they can find mypodcast.
That's when they can read up oninterviews that we've done in
the past, and they can alsoreach out to me there.
Anti-aging Hacks H-A-C-K-S.
Speaker 1 (47:53):
Hacks, oh, h-a-c-k-s.
Yes, hacksnet Dot net.
Yes, okay, got it.
Okay.
Well, thank you, it was reallya pleasure and, by all means,
let's stay in touch.
Speaker 2 (48:08):
Absolutely, Dr Rooney
.
Thank you.
This was an honor to come onyour show.
Speaker 1 (48:11):
It was a pleasure
having you.
Thank you and bye-bye, bye, bye.
Thanks, dr Rooney.