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February 28, 2025 1 min

Stacey Johnson, NP, a rheumatology specialist at Montana Arthritis Center, discusses key updates in the 2024 American College of Rheumatology (ACR) guidelines for lupus nephritis, with a strong emphasis on minimizing glucocorticoid exposure to prevent long-term complications.

The updated guidelines focus on achieving a daily glucocorticoid dose of 5 mg or less within six months of initiating therapy. This approach aims to reduce steroid-related adverse effects such as osteoporosis, cardiovascular risks, and metabolic disturbances while maintaining disease control. To achieve this, clinicians must closely monitor disease activity and tailor tapering strategies to each patient’s individual needs.


Frequent patient assessments and laboratory monitoring play a crucial role in ensuring stability throughout the tapering process. Identifying early signs of disease worsening is essential to making timely adjustments and preventing potential flares. By adopting a personalized approach, healthcare providers can optimize outcomes and improve the long-term management of lupus nephritis.


For more expert insights on lupus nephritis treatment strategies, visit the RhAPP website or explore additional educational content on the RhAPP ACE App.

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