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July 1, 2025 67 mins

Behind many chronic symptoms is one unseen disruptor: your toxic load.

You’ve cleaned up your diet, run the basic labs, maybe even tried supplements,... so why do symptoms like brain fog, fatigue, or hormonal shifts keep lingering? In this conversation, we zoom in on what standard care often misses: the toxins building up in your body and their effects on your gut, brain, and immune system long before a diagnosis ever appears. 

Our guest, Dr. Tom O’Bryan, explains why autoimmunity and cognitive decline don’t start overnight and the early patterns for detection He also encourages how specialized tests like the Total Toxin Burden and Neuro Zoomer can uncover root causes that aren’t always obvious, especially when traditional labs come back “normal.” 

Tune in to learn how functional medicine can help you identify what’s really driving your symptoms and what you can do about it.

Episode Timeline: 

0:00 — Podcast Intro

0:36 — Welcome Message & Disclaimer

2:10 — Meet Dr. Tom O’Bryan

3:29 — How Infertility Sparked Dr. Tom’s Career

5:33 — The Inflammation Link Behind Hormone Issues

8:04 — How Plastic Chemicals Affect Your Child’s IQ

10:48 — Glyphosate and Sperm Health

13:19 — Why Fertility Clinics Miss the Root Cause

18:03 — Should You Test or Just Detox?

20:50 — Preconception and Generational Health

23:03 — Gut Health Explained: The Cheesecloth Analogy

25:21 — Leaky Gut and Food Sensitivities

26:59 — Leaky Brain and Inflammation Risks

29:21 — The “I Feel Fine” Syndrome: Why Early Testing Matters

32:31 — Alzheimer's and the 25-Year Prodromal Period

39:27 — The Autoimmune Spectrum: From Normal to Diagnosis

41:35 — Inflammation: The Real Root Cause Behind Chronic Disease

45:33 — A Call to Test: Know What You're Dealing With

46:53 — Mold, Brain Fog, and the Missed Environmental Triggers

50:36 — Why “You’re a Mess” Can Be Good News

53:11 — Is European Wheat Safer? The Real Reason It Feels Better

56:18 — Thank You Message for Guest

56:38 — Where to Find Dr. Tom O’Bryan

57:03 — Podcast Outro

57:25 — Key Takeaways

About Tom O’Bryan: 

Dr. O’Bryan is considered a ‘Sherlock Holmes’ for chronic disease and teaches that recognizing and addressing the underlying mechanisms that activate an immune response is the map to the highway towards better health. He holds teaching Faculty positions with the Institute for Functional Medicine and the National University of Health Sciences.

Connect with Tom O’Bryan: 


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