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September 18, 2025 46 mins

Johann Hari, author of The Magic Pill, chats with Chrissy about the rise of new weight loss drugs like Ozempic and what they reveal about our culture, our food, and our bodies. Together, they explore the science, the stigma, and the deeper emotional truths around eating, health, and self-acceptance.


Key Takeaways

  • How weight loss drugs like Ozempic, Wegovy, and Mounjaro actually work on appetite, the gut, and the brain.
  • Why obesity rates have skyrocketed in recent decades, and the role processed foods play in undermining our natural fullness signals.
  • The profound psychological impacts of these drugs—from freedom from obsessive food thoughts to potential risks for eating disorders.
  • How shame, cultural judgment, and outdated ideas about “willpower” distort the way we see weight, health, and body image.
  • Practical tools for shifting toward body appreciation and self-compassion, including body functionality practices and loving-kindness meditation.


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