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February 27, 2025 21 mins

101. Ketamine for Emotional Healing: Divorce, Depression, and Dosing with Kaia Roman

What happens when your life falls apart—and a new path reveals itself through ketamine-assisted therapy? In this vulnerable and science-savvy episode, April Pride talks with Kaia Roman, author of The Joy Plan, about using ketamine for emotional healing during divorce and lockdown. Kaia breaks down how different types of ketamine administration affect your brain, what it actually feels like to dissociate, and why set and setting are non-negotiables. Whether you’re skeptical of psychedelics or searching for a safe reset, this conversation blends research, real talk, and deeply personal insights on what it means to grow through rupture.

🔵 Key Takeaways

-Ketamine can help interrupt depressive loops and open windows for rewiring the brain—especially during high-stress events like divorce.

-Intramuscular injections may offer a deeper experience than IV or lozenges, though dosage control is trickier.

-At-home ketamine lozenges offer accessibility and affordability—but sublingual absorption is only ~25% compared to other methods.

-Spravato, the nasal S-ketamine, is FDA-approved but may activate opioid receptors, making it less ideal than clinical or at-home lozenge treatments.

-Integration support is crucial. Post-session neuroplasticity offers a rare chance to rewire thought patterns and behaviors.

Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/ketamine-for-emotional-healing-divorce

Hosted by April Pride

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