298. Breast Cancer: Perimeter Medical’s AI Platform Slashes Re-Excisions and Costs in Breast Cancer Treatment

Episode breakdown:

00:00 – Tech Problems, AV Chaos, and Starting the Conversation

00:50 – Meet Adrian Mendes, CEO of Perimeter Medical

01:27 – How Perimeter Got on the Radar (and Chamath’s Backing)

02:17 – Chamath Explains the Breast Cancer Surgery Problem

04:47 – AI + Imaging to Eliminate Repeat Surgeries

06:34 – FDA Trials, Labeling, and the Road to Approval

07:23 – The Emotional and Clinical Impact of Re-Excisions

08:35 – How Surgeons Use Perimeter’s Current FDA-Cleared Device

09:52 – $700M Wasted Annually on Repeat Surgeries

10:59 – Cutting Re-Excisions to 5%: Hospital and Patient Benefits

12:07 – Why Medtech Needs Both Clinical and Economic Pathways

12:58 – Adrian’s AI Hardware Background and Move to Medtech

14:55 – How Optical Coherence Tomography (OCT) Works in the OR

16:27 – Imaging Comparison: OCT vs. Ultrasound vs. MRI vs. Pathology

17:59 – Building an AI + OCT Platform and Tissue Registry

19:22 – The Scale of the Market Opportunity Beyond Breast Cancer

20:55 – Why Breast Cancer Was the Beachhead Market

21:53 – Perimeter’s Business Model: Capital, Disposables, and AI Software

23:33 – Adoption, Workflow Integration, and Surgeon Response

25:49 – Confidence, Data, and Surgeon Feedback

27:02 – Demand Creation and Word-of-Mouth Growth

28:59 – Workflow Demo: How the Device Is Used in Surgery

30:49 – Patient Impact: Rural Access and Reduced Delays

32:31 – AI Levels the Playing Field for Community Hospitals

33:53 – PMA Submission and AI Clinical Trial Results (88.1% Accuracy)

35:57 – The Emotional Benefit of “First-Time-Right” Cancer Surgery

37:20 – Regulatory Progress and Commercial Updates

38:44 – Chamath’s Involvement and Why AI Differentiates Perimeter

40:05 – Quality Data vs. Big Data: Building a Proprietary Library

41:13 – Predictive Health, Earlier Detection, and Future Applications

42:24 – TechMed vs. Medtech: Why Perimeter Is a True Hybrid

43:07 – Looking Ahead: More Indications and Expanding Applications

43:53 – Closing Thoughts and Call to Action

Are you a medtech CEO in need of some marketing help attracting investors, growing sales pipeline, and more? Go to GrowMyMedtech.com to book time for a free analysis.

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