Today in episode # 8 I'll be reviewing the role of hypertension, obesity, type 2 diabetes and heart disease (cardiometabolic disease), and insulin resistance in your risk for late-onset Alzheimer's disease (LOAD).
The metabolic and biochemical pathways by which cardiometabolic disease increases the risk for dementia and Alzheimer's later life is the central theme in my book: The Diabetic Brain in Alzheimer's Disease.
The book thoroughly describes how and why the most prevalent age-related disorders of our time, put your brain and you at great risk for either vascular dementia, type 3 diabetes, and Alzheimer's disease in later life.
And, this episode provides a summary on how obesity and cardiometabolic disease drive pro-inflammatory pathways and insulin resistance in the body and brain. and subsequently increase the risk for LOAD.
Plus, I'll also provide an overview about a couple of very important biomarkers risk factors—hemoglobin A1c and advanced glycation end-products (AGEs)— that are prime risk factors for not only diabetes and heart disease, but also for cognitive decline, dementia and Alzheimer's disease.
Laboratory assessments of those very biomarkers, and many others are critical risk factors that you and your physician can track and leverage for a proactive intervention and dementia risk reduction approach.
Hemoglobin A1c and fasting glucose are biomarkers that are easily and widely available on blood tests and these biomarkers and many others should be carefully monitored as one ages—particularly if there is a family history of cardiometabolic disease, dementia, or late-onset Alzheimer's disease.
Please listen in!
Ralph Sanchez, MTCM, CNS, D.Hom
BrainDefend®
https://www.facebook.com/TheAlzheimersSolution
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