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March 30, 2025 122 mins

Cancer is one of the most terrifying illnesses of our age - a sudden change that happens silently inside our bodies and slowly eats away at us until there’s nothing left. It’s also one of the biggest failures of the pharmaceutical age - somewhere between 90 and 97% of all cancer drugs fail at clinical trials. Which is why we’re unbelievably excited to bring you our conversation with Dr. Thomas Seyfried, Professor of Biology at Boston College who appears to be hot on the trail of a cure cancer that has nothing to do with the oncology-industrial-complex. According to the dozens of papers he and his colleagues have published over the last few decades, a strict ketogenic diet coupled to a glutamine inhibitor is sufficient to weaken cancer cells to the point that the immune system can actually clear the tumor. A recent paper from his group published in February of 2025 shows the stunning effects of his protocol in a small group of eighteen glioblastoma patients. Median survival for these patients for the last hundred years has been 12-15 months, but with Seyfried’s intervention appears to have been extended up to 84 months. That’s seven years, for those keeping score.We sit down with Seyfried to take apart his protocol, why it works for cancer, why no one’s heard if it, and how everyone has completely misunderstood what cancer actually is.MAKE HISTORY WITH US THIS SUMMER:https://demystifysci.com/demysticon-2025PATREON https://www.patreon.com/c/demystifysciPARADIGM DRIFThttps://demystifysci.com/paradigm-drift-show(00:00) Go!(00:07:33) - Reception of Metabolic Cancer Research(00:10:05) - Breakthrough in Glioblastoma Treatment(00:14:49) - Glutamine-Glutamate Cycle in Cancer(00:16:33) - Challenges and Critiques of Standard Care(00:17:43) - Barriers to Implementing Metabolic Therapies(00:24:19) - Radiation and Cancer Treatment(00:26:07) - Metabolic Approach to Cancer(00:27:30) - Evolutionary Biology's Role in Understanding Cancer(00:28:52) - Mitochondria's Role in Cellular Destiny(00:31:39) - The Oxidative Phosphorylation Process(00:35:28) - Cancer and Mitochondrial Function(00:38:43) - Cellular Electrochemical Gradients(00:41:30) - Cancer's Dependency on Fermentable Fuels(00:45:08) - Glutamine's Role in Cancer Treatment(00:52:11) - Patient Compliance and Dietary Challenges(00:55:33) - Glucose Ketone Index for Health Monitoring(01:06:48) - Fenbendazole and Cancer Research(01:10:02) - Medical Industry Business Models(01:13:27) - Diets and Nutritional Ketosis(01:17:06) - Metabolic Variability and Personalization(01:19:25) - Exercise and Metabolic Health(01:23:43) - Historical Misconceptions in Cancer Treatment(01:26:21) - Obesity and Cancer Prevention(01:28:00) - Metabolic Theories of Cancer(01:47:18) - Metastatic Cancer Origins(01:55:24) - Therapeutic and Collaborative Approaches(01:59:57) - Practical Steps and Transformations#CancerResearch, #glioblastoma, #CancerAwareness, #Oncology, #CancerTreatment, #CancerSurvivor, #FightCancer, #EndCancer, #CancerSupport, #ClinicalTrials, #CancerWarrior, #BeatCancer, #CureCancer, #CancerFighter, #StayStrong, #CancerCommunity, #philosophypodcast, #sciencepodcast, #longformpodcast ABOUS US: Anastasia completed her PhD studying bioelectricity at Columbia University. When not talking to brilliant people or making movies, she spends her time painting, reading, and guiding backcountry excursions. Shilo also did his PhD at Columbia studying the elastic properties of molecular water. When he's not in the film studio, he's exploring sound in music. They are both freelance professors at various universities. SOCIAL: - Discord: https://discord.gg/MJzKT8CQub- Facebook: https://www.facebook.com/groups/DemystifySci- Instagram: https://www.instagram.com/DemystifySci/- Twitter: https://twitter.com/DemystifySciMUSIC: -Shilo Delay: https://g.co/kgs/oty671

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