Wegovy vs. Zepbound: Which Is Right for Me?

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Zepbound or Wegovy—Which One Should You Choose?

That’s what we’re diving into today. Which medication is the better fit? What are the pros and cons? Plus, there are some important updates—new approved uses, cost changes, and more.

Before we get started, a quick note: I’m recording this on March 12, 2025, and things are evolving quickly with these medications. Labels, indications, and guidelines may change, so if you're listening in the future, be sure to check for the latest information.

Also, for full transparency—I do have a financial interest in these medications, particularly Zepbound. I believed in it early on, invested in Eli Lilly before its release, and now work as a speaker for the medication, sharing information with doctors. That said, my goal isn’t to push one over the other but to lay out the facts so you can make the best decision for yourself.

Here’s what we’ll cover today:

• Wegovy vs. Zepbound: A Guide to Choosing the Right Weight Loss Medication
• Approved Uses – What are these medications officially approved for?
• Which Leads to Greater Weight Loss? – A look at the data.
• Side Effects of Wegovy and Zepbound – What to watch out for.
• Key Differences in Side Effects – How these medications compare.
• The Role of Cost and Insurance Coverage – Affordability matters.
• Exploring Other Options – What else is out there?

Be sure to listen to the full episode because there’s a lot to unpack here. The differences between these medications aren’t always straightforward, and factors like cost, availability, and side effects can play a big role in your decision. By the end, you’ll have a clear picture of which one makes the most sense for you. Let’s get into it.

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