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May 26, 2025 19 mins

Claim your complimentary gift of my exclusive mini weight care guide today!

Link: Weight Care Guide — Dr. Francavilla Show (thedrfrancavillashow.com)

Ever lost a lot of weight like 40, 50 pounds or more and noticed some unexpected changes in your body?

In today’s episode, we’re talking about the surprising (and sometimes downright weird) side effects that don’t get mentioned much when it comes to major weight loss—whether it’s from lifestyle changes or medications like Zepbound or Wegovy.

For example, some people develop Eustachian tube dysfunction, which can make your ears feel blocked or pop unexpectedly. Sitting might even feel uncomfortable now that the fat cushioning your tailbone is gone.

Then there’s “slimmer’s paralysis”—a temporary nerve irritation that can pop up when the fat around certain nerves disappears. You might also spot new lumps or bumps, or find yourself feeling colder than usual since fat helps keep you warm.

Other changes can include lower blood pressure and shifts in your menstrual cycle as your body adjusts.

Want to hear more about these lesser-known effects and how to deal with them? Tune in to the full episode!

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