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November 14, 2025 11 mins

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We challenge the myth of inevitable cognitive decline and show how neuroplasticity stays alive through novelty, skill learning, and emotional practice. Curiosity, movement, and mindful engagement build memory, focus, and resilience at any age, turning aging into active refinement.

• rejecting the decline myth for lifelong plasticity
• the brain as a garden that can be cultivated
• novelty as the strongest driver of new connections
• repetition polishing skills versus uncertainty building circuits
• social and mental activity supporting memory, attention, regulation
• skill-based learning increasing gray matter and BDNF
• mindfulness, empathy, gratitude integrating prefrontal and limbic systems
• aging as refinement through intentional practice and curiosity
• one simple action this week to spark growth

This week, just do one thing your brain has genuinely never done before


This podcast is created by Ai for educational and entertainment purposes only and does not constitute professional medical or health advice. Please talk to your healthcare team for medical advice.

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Episode Transcript

Available transcripts are automatically generated. Complete accuracy is not guaranteed.
SPEAKER_01 (00:00):
Welcome to the deep dive.
Today we're looking into afascinating stack of sources all
about the aging brain, ourmission to challenge that um
that really old idea thatcognitive ability just locks in,
or worse, declines once you passa certain age.
Yeah.
I mean, we all kind of grew upwith this slightly depressing

(00:21):
assumption, didn't we?
That the brain was like, I don'tknow, a circuit board.
Once it was wired up, that wasbasically it.
And any change from then on wasjust downhill, wire spraying,
decline, inevitable.

SPEAKER_00 (00:31):
Aaron Powell Well, thankfully that view is um
pretty much obsolete.
Modern neuroscience paints avery different picture.
Much more hopeful one, actually.
It is.
It comes down to this coreconcept neuroplasticity.
And this isn't just some, youknow, nice-to-know fact.
It means the brain keeps itsability to adapt its entire
life.

SPEAKER_01 (00:49):
It's entire life, really.

SPEAKER_00 (00:50):
Yes.
Forming new connections,strengthening the ones it has,
even uh generating new neurons.
The sources use an analogy Ireally like.
Oh, yeah.
They said your brain isn't likea rigid machine that just wears
out, it's more like a livinggarden.

SPEAKER_01 (01:02):
Aaron Powell A living garden.
I find that really powerful,actually.
A machine breaks down, right?
But a garden?
Well, you can always cultivate agarden.

SPEAKER_00 (01:10):
Exactly.
It can always be worked on,improved, changed.

SPEAKER_01 (01:13):
So, okay.
The goal for this deep dive thenis to understand how that garden
works, especially as we getolder.
Aging doesn't just like flip aswitch and turn off plasticity.

SPEAKER_00 (01:23):
Aaron Powell No, not at all.
It just maybe asks us to be abit more intentional about using
that ability.

SPEAKER_01 (01:28):
Right.
So the potential, theinfrastructure for growth, it's
always there.

SPEAKER_00 (01:33):
Always.
The real question for anyonelistening is, you know, are you
still planting seeds?
Are you tending that garden?

SPEAKER_01 (01:39):
Aaron Powell Okay, let's unpack that.
If the goal is keeping thatcognitive garden uh flourishing
throughout life, what's the mainfuel?
What keeps neuroplasticitygoing?

SPEAKER_00 (01:49):
Aaron Powell The number one thing the brain
craves, essentially, is novelty.

SPEAKER_01 (01:52):
Novelty, okay.

SPEAKER_00 (01:53):
Yeah.
Anything new is like a signalflare to the brain.
It says, pay attention.
This is important.
We need resources here.
So we're talking new ideas, newmovements, trying a new
language, even just, you know,looking at something familiar in
a completely different way.

SPEAKER_01 (02:07):
Aaron Powell But hang on.
Novelty.
It sounds kind of tiring,doesn't it?
I mean, we develop routines fora reason, right?
They save energy.
What about just getting really,really good at something complex
you already do, like masteringcoding or perfecting your tennis
serve?
Isn't that just as good asconstantly chasing the new?

SPEAKER_00 (02:25):
Aaron Powell That's a really important distinction
the sources bring up.
Repetition, like perfecting aserve, definitely builds
expertise.
It strengthens an existingpathway.
Very useful.

SPEAKER_01 (02:36):
Okay.

SPEAKER_00 (02:36):
But the strongest trigger for plastic change, for
building genuinely newconnections, seems to require
the brain to face uncertainty,to grapple with something it
hasn't quite figured out yet.

SPEAKER_01 (02:46):
So it needs that struggle, that feeling of not
quite knowing.

SPEAKER_00 (02:49):
It seems so.
Yeah.
The brain is always doing thissort of background check, asking
what pathways are we actuallyusing.
And if you start giving itgenuinely new, challenging
things, well, it starts tothink, okay, we don't need all
this extra wiring foradaptability anymore.
It begins dismantling it.

SPEAKER_01 (03:03):
Wow.
So the flip side is almostscary.
Like the moment your curiositystarts to fade, the brain
interprets that as a signal toprune away your ability to
adapt.

SPEAKER_00 (03:13):
Functionally.
Yeah.
Yeah, that seems to be how itworks.
When we really settle into justautomated routines, the networks
that supported that quicklearning, that flexibility, they
can start to weaken, to pruneaway, as the sources put it.
Curiosity, on the other hand,signals possibility.
It tells your brain life isstill complex, still

(03:33):
interesting, still worthinvesting its structural
resources in, no matter how oldyou are chronologically.

SPEAKER_01 (03:39):
That really puts the responsibility for our own
cognitive health back on us,doesn't it?
On our daily choices to stayinquisitive.
It's actually quite motivating.

SPEAKER_00 (03:48):
And the effects aren't just theoretical, they
show up in measurable ways.

SPEAKER_01 (03:52):
Okay, here's where it gets really interesting,
especially for anyone, you know,tracking their progress or
looking for tangible results.
What specific measurable rewardsdoes the brain give us when we
choose to stay actively engaged?

SPEAKER_00 (04:05):
Oh, the research here is pretty overwhelming.
Study after study confirms it.
People who make a point ofstaying mentally active and
socially active too, which oftenbrings novelty, they maintain
much stronger connectivity andbrain regions linked to
basically three key thingsmemory recalling information,
attention staying focused, andimportantly, emotional

(04:27):
regulation managing yourresponses.

SPEAKER_01 (04:29):
And we're not just talking about, say, doing
crossword puzzles, though that'sgood too, I imagine.
The sources seem to reallyemphasize skill-based
activities.

SPEAKER_00 (04:36):
That's right.
The most powerful changes seemlinked to acquiring new skills
that really demand integration,like your brain and body working
together in a new way.
Such as think about learning amusical instrument, maybe taking
up a complex dance style, oreven a hands-on hobby like
pottery or coding, as youmentioned, things that require
coordination, learning patterns,fine motor skills.

SPEAKER_01 (04:58):
And doing that doesn't just feel good or
stimulating, it actually changesthe brain structure.

SPEAKER_00 (05:03):
Yes.
It directly leads to ameasurable increase in gray
matter density.
You can actually see it on scansin the specific brain regions
you're using for that new skill.

SPEAKER_01 (05:12):
An increase in gray matter density.
Okay, break that down.
What does that functionally meanfor someone trying to remember a
name quickly or learn some newsoftware?

SPEAKER_00 (05:22):
It means you're literally building more
processing power, moreconnections, faster transmission
lines in that area.
It's like upgrading the hardwarefor that specific task,
increased capacity.

SPEAKER_01 (05:33):
Wow.
And what's driving that changechemically?

SPEAKER_00 (05:36):
Ah, well, that structural change is boosted by
a really key neurochemical.

SPEAKER_01 (05:41):
Yeah.

SPEAKER_00 (05:42):
BDNF.
That stands for brain-drivedneurotrophic factor.

SPEAKER_01 (05:46):
Right.
BDNF, I've heard it called thebrain's own fertilizer, helps
neurons grow and survive.

SPEAKER_00 (05:52):
That's a perfect way to put it, exactly.
When you challenge your brain,especially with tasks involving
learning new movements ornavigating new spaces, you get a
flood of BDNF.
It's like the brain's biologicalreward saying, yes, keep doing
this.

SPEAKER_01 (06:05):
So the challenge itself triggers the reward that
helps build the capacity to meetthe challenge.

SPEAKER_00 (06:09):
Precisely.
And what's really critical here,something the source has
stressed over and over, is thatthe key isn't becoming a
virtuoso.
It's not about perfection.

SPEAKER_01 (06:16):
Oh, that's a relief.

SPEAKER_00 (06:17):
Isn't it?
The brain doesn't demandmastery.
It just demands participation,stimulation.
Simply trying somethingdifficult, even if you feel
clumsy or slow at first, thatattempt is enough to trigger
this growth response.

SPEAKER_01 (06:30):
Aaron Powell Just showing up and engaging is the
signal.

SPEAKER_00 (06:32):
That's the signal.
And you know, what's reallyfascinating is that this deep
plasticity, this ability torewire, isn't just for learning
facts or uh physical skills.
It applies just as much to ouremotional lives.

SPEAKER_01 (06:44):
Aaron Powell That feels incredibly important,
maybe even more critical forjust, you know, long-term
well-being and happiness.
How does something likepracticing empathy or gratitude
actually translate into physicalbrain changes?

SPEAKER_00 (06:57):
Aaron Powell Well, think of them as forms of
emotional learning, and theyabsolutely rewire the brain for
resilience just as effectivelyas learning, say, math problems
does.
They require a high level ofintegration in the brain.

SPEAKER_01 (07:08):
Aaron Powell Integration between what parts?

SPEAKER_00 (07:10):
When we consciously practice things like mindfulness
or putting ourselves in someoneelse's shoes, feeling gratitude,
we are strengthening thephysical connections, the
communication lines between tworeally crucial brain areas.

SPEAKER_01 (07:22):
Aaron Powell Okay, which ones are we talking about?

SPEAKER_00 (07:23):
Aaron Powell We're talking about the prefrontal
cortex.
Yeah.
Sort of think of that as thebrain CEO.
It handles reasoning, planning,impulse control.

SPEAKER_01 (07:31):
Trevor Burrus, Jr.: The rational part.

SPEAKER_00 (07:32):
Right.
The executive function hub.
And we're strengthening itsconnection to the limbic system.
That's more like the coreemotional engine processing,
fear, desire, immediate gutreactions.

SPEAKER_01 (07:43):
Aaron Powell So practicing things like
mindfulness is essentiallybuilding a better, faster
communication channel betweenthe rational CEO and that
sometimes quite noisy emotionalengine room.

SPEAKER_00 (07:54):
Aaron Powell That's precisely it, beautifully put.
These practices physicallycreate greater integration
between those systems.
And what that allows us to do isrespond to life's stresses with
more, well, wisdom rather thanjust reacting on impulse.

SPEAKER_01 (08:08):
Aaron Powell, which sounds like the definition of
emotional maturity, really.

SPEAKER_00 (08:10):
It really is.
And this ability to integratereason and emotion, this
constant balancing act, theflexibility in both thought and
feeling, that's the truehallmark of a healthy adaptive
mind.
It doesn't matter if you're 25or 75.
Mental flexibility and emotionalwisdom are like two sides of the
same neuroplastic coin.

SPEAKER_01 (08:28):
Okay, so let's pull back and connect all these dots.
If this neuroplasticity, thisadaptability and skills and
emotions, is the engine ofvitality throughout life, what
does this really mean for how weshould think about aging itself?

SPEAKER_00 (08:40):
Aaron Powell I think it means we have to completely
throw out that old, frankly,depressing narrative of passive
decline.
It's just not accurate.

SPEAKER_01 (08:48):
Aaron Powell So what's the alternative
narrative?

SPEAKER_00 (08:50):
Aaron Ross Powell The sources suggest the aging
brain doesn't just fade away.
It refines.
It gets incredibly efficient,actually.
It learns through experience tofilter out the noise, to focus
resources on what truly matters.
It's almost like a form ofcultivated wisdom emerging from
the structure itself.

SPEAKER_01 (09:06):
Aaron Powell And we can actively participate in that
refinement?
Speed it up, maybe?

SPEAKER_00 (09:11):
Yes, absolutely.
Through consistent consciouspractice, by choosing curiosity,
by keeping our bodies moving, bystaying socially engaged.
We can actively extend thisadaptability deep into our later
years.
It really is a kind oftransaction.

SPEAKER_01 (09:25):
The transaction.

SPEAKER_00 (09:26):
Yeah.
The brain rewards us withcontinued vitality, with
resilience, but only if we keepengaging, if we keep pending
that garden.

SPEAKER_01 (09:33):
So the big takeaway from this deep dive, for me at
least, is that aging feels lesslike some predetermined decline
we just have to accept, and muchmore like an evolution we can
actually steer.

SPEAKER_00 (09:45):
I agree.
Your brain is this incrediblydynamic landscape.
It's responding literally momentby moment to how you choose to
live.
Yeah.
Every time you try a new skill,puzzle over a complex idea, or
even just choose compassion overreactivity, you are physically
rewiring it.

SPEAKER_01 (10:01):
It's listening.

SPEAKER_00 (10:02):
It's definitely listening.
And the goal isn't really aboutkeeping the brain young that
feels passive somehow.
The real measure of success, Ithink, is keeping it awake,
keeping it engaged and alert.

SPEAKER_01 (10:12):
So for you listening right now, maybe take a second.
Think about what specificallysparks that feeling for you,
that little jolt of alertness,maybe even slight
disorientation.
That comes with genuinediscovery.

SPEAKER_00 (10:22):
Where do you find that in your daily life?

SPEAKER_01 (10:24):
And if you want a really concrete way to uh
kickstart this process, mayberight now or this week, the
sources offered astraightforward action step.

SPEAKER_00 (10:33):
Yeah, it was simple.
This week, just do one thingyour brand has genuinely never
done before.

SPEAKER_01 (10:38):
It doesn't have to be huge.

SPEAKER_00 (10:39):
Not at all.
Don't worry about mastering it.
Just try it.
Maybe take a totally new routehome from work, deliberately get
lost without GPS for a bit.
Or try cooking a recipe withingredients you can't pronounce.
Or uh even just attempt to writea simple haiku about your day.

SPEAKER_01 (10:55):
The point is the attempt.

SPEAKER_00 (10:56):
Exactly.
Just notice that spark when youdo it, that little signal of
alertness.
That's your brain confirminggrowth is happening.
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