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April 7, 2025 32 mins

#242: In this episode, Sharif and Dr. Kevin Majeres discuss the nature of addiction. They begin by exploring its development, showing how addiction often starts as a pursuit of pleasure but can evolve into a compulsive behavior that undermines personal ideals and freedom. The conversation focuses on the neuroscience of addiction, highlighting the role of the brain's dorsal striatum in compulsive behaviors. Dr. Majeres explains how the shift from the ventral to the dorsal striatum marks a transition from pleasure-seeking to compulsion, driven by dynorphins. The discussion also covers the nature of habits, the importance of reframing and mindfulness in breaking addiction cycles, and strategies for recovery.


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