What if your skincare routine could go beyond aesthetics and actually slow aging at the cellular level?
In this episode of The Wellness Roundtable: Longevity, Alexia Brue sits down with Carolina Oliveira, MD / co-founder and CEO of OneSkin, a biotech company on a mission to transform skin from a cosmetic afterthought to a longevity biomarker.
Dr. Oliveira shares how her team of scientists developed OS-01, the first topical peptide shown to reduce the burden of senescent cells in skin. We explore the clinical validation behind the product, why “skinspan” matters for your healthspan, and how your skin’s biological age may be a bellwether for systemic inflammation and immune health.
This is not your average skincare chat—it’s a science-backed conversation about the future of personalized longevity, from barrier function to bioinformatics.
This episode also features insights from Beth McGroarty, VP of Research & Forecasting at the Global Wellness Institute.
Inside This Episode:
- Why skin is more than cosmetic: it’s a modifiable aging organ
- The role of senescent cells in driving systemic inflammation
- How OneSkin developed and validated its OS-01 peptide
- The surprising link between topical products and internal biomarkers
- What most longevity enthusiasts overlook about skin health
- How OneSkin is earning credibility with leaders like David Sinclair and Peter Diamandis
- Daily protocols: How Dr. Oliveira approaches her own longevity stack
Resources & Mentioned:
- OneSkin’s OS-01 peptide
- Mentions: David Sinclair, Peter Diamandis, Bryan Johnson
Hosted by: Alexia Brue, co-founder of Well+Good; founder of a new healthspan training studio, The Practice; member of the Global Wellness Institute Board of Advisors
To learn more about the Global Wellness Institute please visit us at global wellness institute.org, connect with us on Instagram and subscribe to our YouTube channel.
Produced by: Emily Roberts and Ali Alquiza of Over Lunch
Music provided by: Myndstream
Thank you to our sponsor, Fountain Life, for supporting the GWI Podcast. Head to FountainLife.com to learn more.
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