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May 8, 2025 41 mins

Bill Gates announced this week that he will shutter his philanthropic foundation in 20 years – but not before using it to give away $200 billion to fight global diseases. In this archival episode from 2019, he tells host Reid Hoffman the story of how it all started – and how he learned to scale his impact as a philanthropist.

In Part 2 of this special two-part conversation, we’re talking with Bill Gates about the biggest success story ever told on the podcast. It was achieved not through Microsoft, but through the Bill & Melinda Gates Foundation. Bill and Melinda have built their foundation into one of the world’s single largest private philanthropies, and they’ve done it by taking lessons learned at Microsoft – on how to massively capitalize on inflection points – and applied them to the nonprofit world. With some surprises along the way. Here's their story. 

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