Have you ever felt like you've hit a plateau at the gym? What if I told you there’s a biological handbrake in your cells that’s actively stopping your muscles from growing? In this episode, we're diving into the science of myostatin, the protein that puts a ceiling on your muscle potential, and how new drugs in development could change medicine and fitness forever.
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CHAPTERS:
00:00 - Intro
00:44 - What Is Myostatin?
01:51 - How Myostatin Limites Muscle Growth
03:41 - The Origins of Myostatin Interest
05:37 - Myostatin and Weight Loss
07:07 - Regeneron’s Recent Study
08:37 - COURAGE Trial
10:39 - Myostatin and Sarcopenia
12:14 - Myostatin and Muscular Dystrophy
13:02 - Myostatin and Spinal Muscular Atrophy
14:14 - Eli Lilly’s Drug
15:24 - Myostatin for sports
17:35 - Safety Considerations
19:29 - Key Takeaways
21:10 - Outro
SELECTED REFERENCES:
https://www.ahajournals.org/doi/10.1161/circresaha.116.308391
https://www.pnas.org/doi/10.1073/pnas.1707925114
https://pmc.ncbi.nlm.nih.gov/articles/PMC6909929/
https://jamanetwork-com.usu01.idm.oclc.org/journals/jamanetworkopen/fullarticle/2774903
https://newsroom.regeneron.com/news-releases/news-release-details/interim-results-ongoing-phase-2-courage-trial-confirm-potential
Disclaimer
This podcast is for entertainment, education, and informational purposes only. The topics discussed should not solely be used to diagnose, treat , or prevent any condition. The information presented here was created with an evidence based approach, but you please keep in mind that science is always changing and at the time of listening to this there may some new data that makes this information incomplete or inaccurate. Always seek the advice of your personal physician or qualified health care provider for questions regarding any medical condition
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