What happens when one man dares to defy centuries of tradition, burn the textbooks of the great masters, and insist that truth lives not in authority, but in direct experience?
In this episode, we journey into the life and mind of Paracelsus (1493–1541)—the fiery Swiss physician, alchemist, and philosopher who turned medicine upside down. Known as the father of toxicology and an early pioneer of holistic healing, Paracelsus believed that the body, mind, and spirit must all be treated together. His radical declaration that “the dose makes the poison” laid the groundwork for modern pharmacology, while his courage to challenge authority anticipated the scientific method itself.
We’ll explore five transformative lessons from his life:
1.Experience Over Authority – Why experiments matter more than tradition.
2.The Dose Makes the Poison – The balance principle shaping medicine, habits, and life.
3.Healing as Mind–Body–Spirit Unity – The holistic vision ahead of its time.
4. Courage to Defy Tradition – The power of burning outdated rulebooks.
5.Nature as the True Teacher – How the world around us still holds the deepest wisdom.
Along the way, we’ll uncover how his radical ideas anticipated psychology, influenced modern science, and still offer practical steps to reshape how we live, work, and heal today.
Paracelsus wasn’t just a physician—he was a rebel, a visionary, and a reminder that progress begins with daring to think differently.
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Paracelsus (1493–1541), born Philippus Aureolus Theophrastus Bombastus von Hohenheim, was a Swiss physician and alchemist who redefined the very nature of medicine. He rejected the dominance of ancient authorities like Galen and Avicenna, preferring hands-on study of the body, disease, and nature. He pioneered toxicology with his principle “The dose makes the poison”, and believed healing required an understanding of not just the body, but also the mind and spirit. He scandalized universities by publicly burning medical textbooks, but in doing so, he cleared the ground for modern medical science.
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FUN FACT: Paracelsus carried a sword with a secret compartment in the hilt—where he kept his handwritten formulas and alchemical notes. He was as much a wandering warrior as a physician, embodying his belief that healing required courage as well as knowledge.
On Purpose with Jay Shetty
I’m Jay Shetty host of On Purpose the worlds #1 Mental Health podcast and I’m so grateful you found us. I started this podcast 5 years ago to invite you into conversations and workshops that are designed to help make you happier, healthier and more healed. I believe that when you (yes you) feel seen, heard and understood you’re able to deal with relationship struggles, work challenges and life’s ups and downs with more ease and grace. I interview experts, celebrities, thought leaders and athletes so that we can grow our mindset, build better habits and uncover a side of them we’ve never seen before. New episodes every Monday and Friday. Your support means the world to me and I don’t take it for granted — click the follow button and leave a review to help us spread the love with On Purpose. I can’t wait for you to listen to your first or 500th episode!
Cardiac Cowboys
The heart was always off-limits to surgeons. Cutting into it spelled instant death for the patient. That is, until a ragtag group of doctors scattered across the Midwest and Texas decided to throw out the rule book. Working in makeshift laboratories and home garages, using medical devices made from scavenged machine parts and beer tubes, these men and women invented the field of open heart surgery. Odds are, someone you know is alive because of them. So why has history left them behind? Presented by Chris Pine, CARDIAC COWBOYS tells the gripping true story behind the birth of heart surgery, and the young, Greatest Generation doctors who made it happen. For years, they competed and feuded, racing to be the first, the best, and the most prolific. Some appeared on the cover of Time Magazine, operated on kings and advised presidents. Others ended up disgraced, penniless, and convicted of felonies. Together, they ignited a revolution in medicine, and changed the world.
Crime Junkie
Does hearing about a true crime case always leave you scouring the internet for the truth behind the story? Dive into your next mystery with Crime Junkie. Every Monday, join your host Ashley Flowers as she unravels all the details of infamous and underreported true crime cases with her best friend Brit Prawat. From cold cases to missing persons and heroes in our community who seek justice, Crime Junkie is your destination for theories and stories you won’t hear anywhere else. Whether you're a seasoned true crime enthusiast or new to the genre, you'll find yourself on the edge of your seat awaiting a new episode every Monday. If you can never get enough true crime... Congratulations, you’ve found your people. Follow to join a community of Crime Junkies! Crime Junkie is presented by audiochuck Media Company.